Author(s): Ellenbogen MA; Serravalle L; Hodgins S; Walker CD; Walker EF;

The offspring of parents with bipolar disorder (OBD) are at high risk for developing affective disorders. Low levels of organization and consistency in the home (parenting structure) is associated with increased behavioral problems and hypothalamic-pituitary-adrenal (HPA) reactivity in the OBD and thus may be an important developmental risk factor. We a ...

Article GUID: 42247738

Author(s): Paul J; Jäger ATP; Huck J; Tardif CL; Villringer A; Gauthier CJ; Bazin PL; Steele CJ;

Ultra-high field magnetic resonance imaging at sub-millimeter resolution opens the possibility to assess subtle longitudinal changes in brain structure and function. Identifying the regions and putative mechanisms involved in learning specific motor sequences is a key step towards understanding neuroplasticity. To disambiguate sequence-specific learning ...

Article GUID: 42237744

Author(s): Abdallah W; Darwish A; Garcia J; Kadem L;

Background: Aortic regurgitation (AR) alters normal blood flow patterns in the left ventricle (LV), affecting diastolic filling dynamics, and is commonly quantified by the regurgitant fraction (RF). However, conventional diagnostic methods have notable limitations, prompting growing interest in four-dimensional flow magnetic resonance imaging (4D-flow M ...

Article GUID: 42228301

Author(s): Brancheriau CR; Larocque K; Schick G; Tountas I; Perlman A; Piekny A;

Cytokinesis, the final step of cell division, relies on ingression of a precisely positioned actomyosin ring. Chromatin-associated Ran-GTP fine-tunes ring position, although the mechanism remains unclear. We hypothesize that depletion of Ran-GTP between segregating chromosomes leads to equatorial enrichment of importins, promoting recruitment of the sca ...

Article GUID: 42225064

Author(s): Calvano A; Xiao Y; Steidel K; Loehrer PA; Ruppert-Junck MC; Nimsky C; Timmermann L; Bopp MHA; Pedrosa DJ;

Purpose: Accurate segmentation of the subthalamic nucleus (STN) is paramount for optimising outcomes under deep brain stimulation (DBS) in Parkinson's disease (PD). Clinically available tools like Brainlab Elements (BL-E) enable automated segmentations for surgical planning, yet their spati ...

Article GUID: 42225900

Author(s): Wang M; Bhagwat N; Cremonesi F; Dugré M; Pfarr JK; d' Angremont E; Dai A; Jahanpour A; Urchs S; Cansiz S; Chambon L; Dinçer AT; Torres J; Vesin M; Pinilla-Monsalve G; Song Y; Vriend C; Jeanson F; Monchi O; van der Werf YD; Lorenzi ...

Despite growing understanding of the benefits of having Findable, Accessible, Interoperable, and Reusable (FAIR) data, many datasets still cannot be shared. Federated analysis methods can enable multisite studies that do not require the sharing of participant-level information. However, there a ...

Article GUID: 42146517

Author(s): Coulter K; Dash T; Best T; Grant N; Ansaldo AI; Phillips NA;

Speaking more than one language is hypothesized to lead to greater brain resilience in aging and Alzheimer's disease, resulting in a delay in the symptom onset of Alzheimer's disease. While previous research has used structural neuroimaging measures to explore the neural underpinnings of this protective effect, few studies have used functional b ...

Article GUID: 42208339

Author(s): Sander-Montant A; Fibla L; Killam H; Byers-Heinlein K;

A persistent challenge in experimental developmental psychology is determining which of many possible outcome measures best captures underlying behaviors and processes. In the looking-while-listening paradigm for studying early word comprehension, researchers have developed more than 12 distinct outcome measures, but have limited empirical basis for cho ...

Article GUID: 42206598

Author(s): Câmara GS; Spiech C; Solli S; Bang B; Rogulina O; Laeng B; Danielsen A;

Musicians convey timing "feels" in groove-based performance by manipulating onset asynchrony between instruments and the durational ratio of metrical subdivisions (non-isochrony, or "swing"). The present study tested whether listeners perceive such fine-grained timing deviations by measuring the just-noticeable difference (JND) thres ...

Article GUID: 42201766

Author(s): Peng C; Liggio J; Moussa SG; Tang Y; Johannessen C; Zhang X; Zhang Z; Li L; Harner T; Saini A; Hung H; Wentzell J; Wheeler MJ; Dabek-Zlotorzynska E; Yassine M; Liu Q; Tang M; Friel-Bartlett Z; Abdul-Sater AA;

Antioxidants added to tires to prevent degradation have recently been recognized as emerging environmental contaminants. While their acute aquatic toxicity has raised concern, these compounds are also emitted to the atmosphere and can be associated with particulate matter (PM). On PM they can r ...

Article GUID: 42191547

Author(s): Cohen TR; Bains A; Ball GDC; Faustini C; Heidl A; Morrison KM;

Few studies have characterized metabolically healthy (MHO) and unhealthy obesity (MUO) in pediatric populations over time. The objective of this study was to determine the prevalence of MHO in children and adolescents enrolled in a weight management program and examine changes in cardiometabolic indicators over 1 year.Methods: Participants from the CANa ...

Article GUID: 42189064