Author(s): Fuoco G; Mandl GA; De Mesa C; Capobianco JA; Naccache R;

Efficient delivery of therapeutics remains a significant challenge, often hindered by solubility barriers encountered within aqueous biological environments. Carbon dots (CDs) offer a promising solution for drug delivery due to their aqueous dispersibility, generally low cytotoxicity and surfaces rich in functional groups which can enable facile conjugati ...

Article GUID: 41288467

Author(s): Hamidabad MN; Mansbach RA;

Antimicrobial peptides (AMPs) are a promising potential solution to combat antimicrobial resistance (AMR) due to their positive charges, which induce selective interaction with negatively charged bacterial membranes. Certain AMPs exhibit a low hemolytic index and non-forming fibrils at physiological pH (7.4), enhancing their therapeutic potential. In this ...

Article GUID: 41256587

Author(s): Côté M; Forouhar V; Sacco S; Baillot A; Himmelstein M; Hussey B; Incollingo Rodriguez AC; Nagpal TS; Nutter S; Patton I; Pearl RL; Puhl RM; Ramos Salas X; Russell-Mayhew S; Alberga AS;

Article GUID: 41280193

Author(s): Thornbury M; Omran RP; Kumar L; Knoops A; Abushahin R; Whiteway M; Martin VJJ;

Organic acids such as fumaric acid are widely used in the food and beverage industry as acidulants and preservatives, while also serving as versatile precursors for industrially relevant compounds. Fumaric acid is still predominantly produced through petroleum-derived processes. To enhance production efficiency and diversify supply, we are engineering Klu ...

Article GUID: 41277095

Author(s): Bellemare-Pepin A; Jerbi K;

Background: The Biotuner Toolbox is an open-source Python toolbox for biosignals that integrates concepts from neuroscience, music theory, and signal processing. It introduces a harmonic perspective on physiological oscillations by applying musical constructs such as consonance, rhythm, and scale construction. Methods: The core biotuner_object processes ...

Article GUID: 41269470

Author(s): Xie K; Sahlas E; Ngo A; Chen J; Arafat T; Royer J; Zhou Y; Rodríguez-Cruces R; Dascal A; Caldairou B; Fadaie F; Barnett A; Audrain S; Larivière S; Caciagli L; Pana R; Weil AG; Grova C; Frauscher B; Schrader DV; Zhang Z; Concha L; Bernasc ...

Temporal lobe epilepsy (TLE) is the most common pharmacoresistant epilepsy in adults, yet few patients receive curative surgery due to diagnostic and prognostic uncertainty. In a multicenter cohort, we analyzed multimodal MRI and clinical data from 282 TLE patients, 298 healthy controls, and 45 d ...

Article GUID: 41258102

Author(s): Sharma B; Negi R; Jyothi SR; Gupta A; Jhamta S; Yadav N; Kaur N; Puri P; Thakur SS; Bagavathiappan S; Thakur N; Shreaz S; Madouh TA; Yadav AN;

According to estimates from United Nations environmental program, salinity affects about 20% of agricultural land and 50% of farmland worldwide. Plants react to salinity stress by undergoing distinctive physiochemical, morphological, and molecular adaptations. Nonetheless, a number of mitigating ...

Article GUID: 41245209

Author(s): Joseph T; Babouras A; Zhao KY; Corban J; Martineau PA;

Background: Anterior cruciate ligament (ACL) tears can be a source of significant morbidity, with the potential for career-altering implications for athletes who sustain them. Specific knee biomechanics during a drop vertical jump have been shown to be associated with an increased risk for ACL injury in collegiate varsity athletes. Presently, the evolutio ...

Article GUID: 41230424

Author(s): Petri RM; Schroeder B; Ronholm J; Ricci S; Escobar J; Andretta I; Tsang A; Pomar C; Remus A;

Understanding the response to enzyme supplementation on body composition and nutrient balance creates the potential to increase nutrient utilization efficiency and, consequently, maximize growth performance in growing pigs. This study aimed to evaluate the effect of fungal lysozyme supplementatio ...

Article GUID: 41206533

Author(s): Kogani A; Yousefzadeh B;

Nonreciprocity is most commonly associated with a large difference in the transmitted energy when the locations of the source and receiver are interchanged. This energy bias is accompanied by a difference in the transmitted phase. This work highlights the role of this phase bias in breaking reciprocity in the steady-state vibration transmission characteri ...

Article GUID: 41201270

Author(s): Quirk E; Brouillard M; Ahooja A; Ballinger S; Polka L; Byers-Heinlein K; Kircher R;

Many parents have concerns about raising their children with multiple languages. However, there is a paucity of previous research regarding parental concerns about multilingual child-rearing, particularly in multilingual societies. We address this gap with a corpus-assisted discourse study of parental concerns regarding multilingual child-rearing in Quebe ...

Article GUID: 41199774