Author(s): Sweidy D; Mathyssen A; Teimouri K; Wei W; Saleh W; Kadem L; Evin M;

Blunt trauma is a major complication of high-speed motor vehicle crashes, often resulting in injuries of varying severity. Cardiac trauma accounts for about 18% of blunt chest injuries, the third most common death cause. Experimental studies described cardiac consequences after impact; however, none have captured the ventricular flow behavior during the i ...

Article GUID: 41934684

Author(s): Ordaz-Morales JE; Juárez-Jiménez AL; Stand-Pérez M; Arce-Valdés LR; Ballén-Guapacha AV; Chávez-Ríos JR; Boasso O; Rajan N; Cordero-Rivera A; Sánchez-Guillén RA;

Theoretical and empirical studies of reinforcement have advanced our understanding of speciation, yet its role in polymorphic species remains understudied. Because morphs differ in behavior, morphology, and reproductive strategies, reinforcement may act unevenly among them, generating asymmetric ...

Article GUID: 41933171

Author(s): Gu Y; Hsu CL; Boa Sorte Silva NC; Tam RC; Alkeridy WA; Lam K; Liu-Ambrose T;

Background: Subcortical ischemic vascular cognitive impairment (SIVCI) is characterized by white matter hyperintensities (WMH) that contribute to executive dysfunction and increased risk of Alzheimer's disease. Cognitive reserve (CR) is the brain's ability to maintain cognitive performance despite pathology. Resting-state functional connectivity ( ...

Article GUID: 41929984

Author(s): Gholizadeh F; Hajiaghayi M; Rahbari N; Choi JS; Heidt S; Como A; Kazerouni M; Kargar M; Pinard-LaRoche A; Shih SCC; Darlington PJ;

Memory T helper (Th) cells sustain protective recall responses but can also drive chronic inflammation, necessitating precise regulation of their effector programs. Although Th cells produce acetylcholine (ACh) and express nicotinic acetylcholine receptors (nAChRs), the contribution of nAChRs to ...

Article GUID: 41928597

Author(s): Volz S; Loewinger G; Marquez I; Fevola S; Kang M; Reverte I; Krishnan A; Gardner MPH; Iordanova MD; Esber GR;

Elucidating the neural substrates of Pavlovian reward learning requires reliable behavioral readouts. In conditioned magazine approach studies, rodents express reward expectancy by approaching the food magazine during cues that predict reward. This behavior is typically quantified using one of th ...

Article GUID: 41922165

Author(s): Parent O; Alasmar Z; Osborne S; Bussy A; Costantino M; Fouquet JP; Quesada D; Pastor-Bernier A; Fajardo-Valdez A; Pichet-Binette A; McQuarrie A; Maranzano J; Devenyi GA; Steele CJ; Villeneuve S; ; Dadar M; Chakravarty MM;

White matter hyperintensities (WMHs) are neuroimaging markers widely interpreted as caused by cerebral small vessel disease, yet emerging evidence suggests that a subset may have a neurodegenerative etiology. Current imaging methods have lacked the specificity to disentangle biological processes ...

Article GUID: 41916976

Author(s): Edwards JD; Li Z; McFarlane P; Rabi DM; Gilbert J; Bajaj HS; MacIntosh BJ; Bittman J; Feldman RD; Dresser G; Terenzi K; Swartz R; Gabor J; Pearson GJ; Selby P; Wharton S; Warburton DER; Pakhalé S; Styra R; Baker B; Tu K; Hawkins M; Stone ...

Background: Although brain and heart conditions share overlapping risk factors and commonly co-occur, current cardiac and neurologic clinical guidelines are typically produced within specialty silos. The objective of this guideline from a Canadian Cardiovascular Harmonized National Guideline Ende ...

Article GUID: 41912243

Author(s): Abraha HN; Gebre AK; Sim M; Smith C; Gilani SZ; Ilyas Z; Zarzour F; Schousboe JT; Lix LM; Binkley N; Reid S; Monchka BA; Kimelman D; Lewis JR; Leslie WD;

Background: Sagittal abdominal diameter (SAD), a measure of visceral adiposity, has been linked to major adverse cardiovascular events (MACE). However, the relationship between SAD and abdominal aortic calcification (AAC), a marker of subclinical vascular disease, and whether they independently a ...

Article GUID: 41903786

Author(s): Bullinger J; Christner N; Urian R; Kellermann CM; Beaulieu S; Steinbeis N; Dunfield KA; Paulus M;

Empathy is vital for social development in early childhood. This study investigates the empathy-related behaviours of 362 German and Canadian children (49.72% girls) aged 3 to 6 years (M = 60.65 months; SD = 11.43 months), focusing on responses to emotional distress. Using latent profile analysis ...

Article GUID: 41888065

Author(s): Brooks M; El Chami R; Jourde HR; Savard MA; Coffey EBJ;

Introduction: Sleep quality is often thought to be a key determinant of cognitive performance, particularly in older adults who experience age-related changes in sleep architecture. However, the extent to which nightly variations in sleep quality impact next-day cognitive performance remains unclear-in part because it has only recently become practical to ...

Article GUID: 41878310

Author(s): Fortin M; Rosenstein B; Bertrand C; Vaillancourt N; Wright A; Montpetit C; Macedo L; Elliott J; Cook CE; Tousignant-Laflamme Y; Ma J; Pagé MG; Dover G; Dang-Vu TT; Weber MH;

Introduction: Exercise therapy is the most recommended treatment for chronic low back pain (LBP), with evidence supporting modest effects, likely due to the heterogeneity of patient presentations. Evidence suggests that matching individuals to the most appropriate exercise type could improve outc ...

Article GUID: 41876162