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Thermo-responsive polysulfobetaine beads crosslinked with biodegradable alginates for controlled release of agricultural pesticide

Author(s): Andrade-Gagnon B; Olszewski C; Bawa KK; Hemraz UD; Oh JK;

The rise in global food demand and the loss in crop production by pests highlight the need for efficient pesticide delivery systems. Stimuli-responsive degradation with thermoresponsive polymers is a promising platform that offers the controlled release of pesticides. Here, we report the development of millimeter-sized thermoresponsive beads (m-beads) com ...

Article GUID: 41561011


Fabrication of thermo-responsive multicore microcapsules using a facile extrusion process

Author(s): Lavertu JD; Bawa KK; Hrapovic S; Fu D; Oh JK; Hemraz UD;

A process employing extrusion was used to produce multicore microcapsules composed of multiple beads. The inner beads were made from ?-carrageenan (?-c), a thermo-responsive linear sulphated polymer whose gelling temperature ranges at 40-60 °C, depending on the concentration of ?-c polymer and the amount of potassium chloride used for gelation. The result ...

Article GUID: 38915334


Imidazole-Mediated Dual Location Disassembly of Acid-Degradable Intracellular Drug Delivery Block Copolymer Nanoassemblies

Author(s): Jazani AM; Shetty C; Movasat H; Bawa KK; Oh JK;

Acid-degradable (or acid-cleavable) polymeric nanoassemblies have witnessed significant progress in anti-cancer drug delivery. However, conventional nanoassemblies designed with acid-cleavable linkages at a single location have several challenges, such as, sluggish degradation, undesired aggregation of degraded products, and difficulty in controlled and o ...

Article GUID: 34050688


Stimulus-Responsive Degradable Polylactide-Based Block Copolymer Nanoassemblies for Controlled/Enhanced Drug Delivery.

Author(s): Bawa KK, Oh JK

Mol Pharm. 2017 08 07;14(8):2460-2474 Authors: Bawa KK, Oh JK

Article GUID: 28493712


PLA-Based Triblock Copolymer Micelles Exhibiting Dual Acidic pH/Reduction Responses at Dual Core and Core/Corona Interface Locations.

Author(s): Bawa KK, Jazani AM, Shetty C, Oh JK

Macromol Rapid Commun. 2018 Dec;39(24):e1800477 Authors: Bawa KK, Jazani AM, Shetty C, Oh JK

Article GUID: 30286258


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