Author(s): Mitchell SW; Chan T; Trudel L; Hosseini SA; Macedo AC; Gonçalves MP; Rahmouni N; Hall BJ; Socualaya KMQ; Therriault J; Servaes S; Bezgin G; Zheng Y; Aumont E; Wang YT; Arias JF; Real APB; Jia WL; Hopewell R; Hsiao C; Soucy JP; Vitali P; ...

Background: Brain and cognitive resilience (BR, CR) reflect the capacity to maintain structural integrity and cognitive function despite pathological tau deposition in Alzheimer's disease (AD). Tau pathology can be characterized in terms of spatial extent of tauopathy (SEOT) or load using sta ...

Article GUID: 41433447

Author(s): Levis B; Benedetti A; Ioannidis JPA; Sun Y; Negeri Z; He C; Wu Y; Krishnan A; Bhandari PM; Neupane D; Imran M; Rice DB; Riehm KE; Saadat N; Azar M; Boruff J; Cuijpers P; Gilbody S; Kloda LA; McMillan D; Patten SB; Shrier I; Ziegelstein R ...

Objectives: Depression symptom questionnaires are not for diagnostic classification. Patient Health Questionnaire-9 (PHQ-9) scores =10 are nonetheless often used to estimate depression prevalence. We compared PHQ-9 =10 prevalence to Structured Clinical Interview for Diagnostic and Statistical Man ...

Article GUID: 32105798

Author(s): Wu Y; Levis B; Riehm KE; Saadat N; Levis AW; Azar M; Rice DB; Boruff J; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; McMillan D; Patten SB; Shrier I; Ziegelstein RC; Akena DH; Arroll B; Ayalon L; Baradaran HR; Baron M; Bombardier CH; ...

Background: Item 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The PHQ-8, which omits Item 9, is thus increasing ...

Article GUID: 31298180

Author(s): Levis B; Benedetti A; Riehm KE; Saadat N; Levis AW; Azar M; Rice DB; Chiovitti MJ; Sanchez TA; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; McMillan D; Patten SB; Shrier I; Steele RJ; Ziegelstein RC; Akena DH; Arroll B; Ayalon L; Bara ...

Background: Different diagnostic interviews are used as reference standards for major depression classification in research. Semi-structured interviews involve clinical judgement, whereas fully structured interviews are completely scripted. The Mini International Neuropsychiatric Interview (MINI) ...

Article GUID: 29717691