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Patterns of Structural Disconnection Driving Proprioceptive Deficits in Chronic Stroke

Author(s): Kaeja M; Gajiyeva L; Iturria-Medina Y; Villringer A; Sehm B; Steele C;

Background: Stroke is a leading cause of death and disability, with proprioceptive impairments affecting up to 64% of survivors. These impairments hinder sensorimotor recovery, significantly impacting poststroke quality of life. Proprioception depends on an integrated brain network but remains underexplored due to limitations in clinical assessments, hind ...

Article GUID: 41392885


Longitudinal relationships among cerebrospinal fluid biomarkers, cerebral blood flow, and grey matter volume in individuals with a familial history of Alzheimer s disease

Author(s): Sanami S; Intzandt B; Huck J; Villeneuve S; Iturria-Medina Y; Gauthier CJ; Prevent-Ad Research Group None;

Alzheimer's disease (AD) is a complex disease that involves complex interactions between protein biomarkers such as amyloid beta (Aß) and tau, neurodegeneration, cerebrovascular health and inflammation. However, how these factors interact, especially in the early phases of disease development ...

Article GUID: 40347524


MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics

Author(s): Tremblay SA; Alasmar Z; Pirhadi A; Carbonell F; Iturria-Medina Y; Gauthier CJ; Steele CJ;

Multivariate approaches have recently gained in popularity to address the physiological unspecificity of neuroimaging metrics and to better characterize the complexity of biological processes underlying behavior. However, commonly used approaches are biased by the intrinsic associations between variables, or they are computationally expensive and may be m ...

Article GUID: 38463982


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