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An In-Vitro simulator for investigating flow disturbances in the left ventricle during controlled external impact

Author(s): Sweidy D; Mathyssen A; Teimouri K; Wei W; Saleh W; Kadem L; Evin M;

Blunt trauma is a major complication of high-speed motor vehicle crashes, often resulting in injuries of varying severity. Cardiac trauma accounts for about 18% of blunt chest injuries, the third most common death cause. Experimental studies described cardiac consequences after impact; however, none have captured the ventricular flow behavior during the i ...

Article GUID: 41934684


Hemodynamic performance and blood damage of the Intra-aortic pumps: A CFD-Based investigation

Author(s): Aycan O; Park Y; Kadem L;

Article GUID: 41863715


A high-fidelity simulator for evaluation of hemodynamic response during cardiopulmonary resuscitation in hypogravity environments

Author(s): Lord Z; Andrade C; Leroux L; Kadem L;

With the emergence of long-duration space travel, space exploration missions pose a major concern due to the heightened risk of medical emergencies, such as sudden cardiac arrest. While several cardiopulmonary resuscitation (CPR) methods have been proposed for human spaceflight, their reliability and effectiveness remain uncertain, as these methods lack s ...

Article GUID: 41741473


Comprehensive review of reinforcement learning for medical ultrasound imaging

Author(s): Elmekki H; Islam S; Alagha A; Sami H; Spilkin A; Zakeri E; Zanuttini AM; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;

Medical Ultrasound (US) imaging has seen increasing demands over the past years, becoming one of the most preferred imaging modalities in clinical practice due to its affordability, portability, and real-time capabilities. However, it faces several challenges that limit its applicability, such as ...

Article GUID: 40567264


Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics

Author(s): Teimouri K; Darwish A; Saleh W; Ng HD; Kadem L;

Purpose: The MitraClip device has emerged as an effective treatment option for patients with mitral regurgitation. However, implementing a MitraClip alters the mitral valve structure and left ventricular flow dynamics. In this study, we experimentally investigate the effects of the MitraClip and the resulting twin pulsed jets on flow dynamics within the l ...

Article GUID: 40325266


CACTUS: An open dataset and framework for automated Cardiac Assessment and Classification of Ultrasound images using deep transfer learning

Author(s): Elmekki H; Alagha A; Sami H; Spilkin A; Zanuttini AM; Zakeri E; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;

Cardiac ultrasound (US) scanning is one of the most commonly used techniques in cardiology to diagnose the health of the heart and its proper functioning. During a typical US scan, medical professionals take several images of the heart to be classified based on the cardiac views they contain, wit ...

Article GUID: 40107020


Numerical investigation of the flow induced by a transcatheter intra-aortic entrainment pump

Author(s): Park Y; Aycan O; Kadem L;

This study evaluates the fluid dynamics inside and outside transcatheter blood pump positioned in the aorta. We focus on the pump's impact on blood component damage and arterial wall stress. CFD simulations were performed for rotational speeds ranging from 6000 to 15000 rpm, with a blood flow rate of 1.6 L/min. Results show that significant blood dama ...

Article GUID: 40014031


Design, manufacturing, and multi-modal imaging of stereolithography 3D printed flexible intracranial aneurysm phantoms

Author(s): Yalman A; Jafari A; Léger É; Mastroianni MA; Teimouri K; Savoji H; Collins DL; Kadem L; Xiao Y;

Background: Physical vascular phantoms are instrumental in studying intracranial aneurysms and testing relevant imaging tools and training systems to provide improved clinical care. Current vascular phantom production methods have major limitations in capturing the biophysical and morphological c ...

Article GUID: 39546636


Design and validation of an In Vitro test bench for the investigation of cardiopulmonary resuscitation procedure

Author(s): El-Khoury A; Leroux L; Dupuis Desroches J; Di Labbio G; Kadem L;

Despite recent clinical and technological advancements, the cardiac arrest survival rate remains as low as 10%. To enhance patient outcomes, it is crucial to deepen the understanding of cardiopulmonary resuscitation (CPR) at a fundamental level. Currently, there is a lack of knowledge on the physiological effects of CPR, in particular on the hemodynamics ...

Article GUID: 39305857


An Anatomically Shaped Mitral Valve for Hemodynamic Testing

Author(s): Darwish A; Papolla C; Rieu R; Kadem L;

In vitro modeling of the left heart relies on accurately replicating the physiological conditions of the native heart. The targeted physiological conditions include the complex fluid dynamics coming along with the opening and closing of the aortic and mitral valves. As the mitral valve possess a highly sophisticated apparatus, thence, accurately modeling ...

Article GUID: 38228812


Spectral-Clustering of Lagrangian Trajectory Graphs: Application to Abdominal Aortic Aneurysms

Author(s): Darwish A; Norouzi S; Kadem L;

Purpose: Identification of coherent structures in cardiovascular flows is crucial to describe the transport and mixing of blood. Coherent structures can highlight locations where minimal blood mixing takes place, thus, potential thrombus formation can be expected thither. Graph-based approaches have recently been introduced in order to describe fluid tran ...

Article GUID: 34845627


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