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Phenogenomics reveals the ecology and evolution of Trichoderma fungi for sustainable agriculture

Author(s): Steindorff AS; Cai FM; Ding M; Jiang S; Atanasova L; Baker SE; Barbosa-Filho JR; Bayram Akcapinar G; Brown DW; Chaverri P; Chen P; Chenthamara K; Daum C; Drula E; Dubey M; Brandström Durling M; Flatschacher D; Ebner T; Emri T; Gao R; Geo ...

Trichoderma fungi support sustainable agriculture by suppressing plant diseases and improving crop performance. However, emerging pathogenicity of Trichoderma warrants further ecological and genetic characterization. Here we used machine learning to correlate genomic data from 37 Trichoderma stra ...

Article GUID: 41775999


Temporal and Sex-Related Differences in Knee Biomechanics Over the Course of the Varsity Athletic Season: Pre- and Postseason Knee Kinematics in Collegiate Varsity Athletes Using Kinect

Author(s): Joseph T; Babouras A; Zhao KY; Corban J; Martineau PA;

Background: Anterior cruciate ligament (ACL) tears can be a source of significant morbidity, with the potential for career-altering implications for athletes who sustain them. Specific knee biomechanics during a drop vertical jump have been shown to be associated with an increased risk for ACL injury in collegiate varsity athletes. Presently, the evolutio ...

Article GUID: 41230424


Modeling the Ethylene Sequence Length Distribution of Metallocene-Catalyzed Bimodal Polyethylene

Author(s): Sattari M; Kwakye-Nimo S; Inn Y; Karimi PA; Wood-Adams PM;

The structure of bimodal poly-(ethylene-hexene) is presented in terms of the ethylene sequence length distribution. This distribution is determined by applying statistical modeling to molecular weight and short chain branching distributions obtained from gel permeation chromatography (GPC). We found that the ethylene sequence length distribution of bimoda ...

Article GUID: 41078728


Inferring concussion history in athletes using pose and ground reaction force estimation and stability analysis of plyometric exercise videos

Author(s): Alves W; Babouras A; Martineau PA; Schutt D; Robbins S; Fevens T;

Concussions present a significant risk to athletes, with females exhibiting higher rates and prolonged recovery times than males. Current sideline concussion detection methods, such as the King-Devick test commonly used as a rapid screening tool designed to evaluate eye movement, attention, language, and cognitive processing abilities suffer from validity ...

Article GUID: 40632382


The Effect of the FIFA-11+ ACL Injury Prevention Program on Drop Vertical Jump Biomechanics in Varsity Athletes: A Prospective Observational Cohort Study

Author(s): Cierson T; Zhao K; Belkhelladi M; Babouras A; Jing J; Faith J; Corban J; Martineau PA;

Background: Anterior cruciate ligament (ACL) injuries can pose significant challenges for athletes, leading to significant morbidity, loss of playing time, and impaired performance. Neuromuscular training programs, such as the FIFA 11+, have shown promise in reducing the risk of lower extremity injuries in this high-risk population. Purpose/hypothesis: T ...

Article GUID: 40303320


Geological Net Zero and the need for disaggregated accounting for carbon sinks

Author(s): Allen MR; Frame DJ; Friedlingstein P; Gillett NP; Grassi G; Gregory JM; Hare W; House J; Huntingford C; Jenkins S; Jones CD; Knutti R; Lowe JA; Matthews HD; Meinshausen M; Meinshausen N; Peters GP; Plattner GK; Raper S; Rogelj J; Stott P ...

Achieving net zero global emissions of carbon dioxide (CO2), with declining emissions of other greenhouse gases, is widely expected to halt global warming. CO2 emissions will continue to drive warming until fully balanced by active anthropogenic CO2 removals. For practical reasons, however, many ...

Article GUID: 39557072


Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles

Author(s): Rezaei M; Liang M; Yalcin Z; Martin JH; Kazemi P; Bareke E; Ge ZJ; Fardaei M; Benadiva C; Hemida R; Hassan A; Maher GJ; Abdalla E; Buckett W; Bolze PA; Sandhu I; Duman O; Agrawal S; Qian J; Vallian Broojeni J; Bhati L; Miron P; Allias F; ...

To identify novel genes responsible for recurrent hydatidiform moles (HMs), we performed exome sequencing on 75 unrelated patients who were negative for mutations in the known genes. We identified biallelic deleterious variants in 6 genes, FOXL2, MAJIN, KASH5, SYCP2, MEIOB, and HFM1, in patients ...

Article GUID: 39545410


Comparing the Drop Vertical Jump Tracking Performance of the Azure Kinect to the Kinect V2

Author(s): Abdelnour P; Zhao KY; Babouras A; Corban JPAH; Karatzas N; Fevens T; Martineau PA;

Traditional motion analysis systems are impractical for widespread screening of non-contact anterior cruciate ligament (ACL) injury risk. The Kinect V2 has been identified as a portable and reliable alternative but was replaced by the Azure Kinect. We hypothesize that the Azure Kinect will assess drop vertical jump (DVJ) parameters associated with ACL inj ...

Article GUID: 38931598


COVID-19 virtual patient cohort reveals immune mechanisms driving disease outcomes

Author(s): Jenner AL; Aogo RA; Alfonso S; Crowe V; Smith AP; Morel PA; Davis CL; Smith AM; Craig M;

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results indicate that virtual patients with low production rates of infected cell derived IFN subsequently experienced highly infla ...

Article GUID: 33442689


Comparing novel smartphone pose estimation frameworks with the Kinect V2 for knee tracking during athletic stress tests

Author(s): Babouras A; Abdelnour P; Fevens T; Martineau PA;

Purpose: To compare the accuracy of the Microsoft Kinect V2 with novel pose estimation frameworks, in assessing knee kinematics during athletic stress tests, for fast and portable risk assessment of anterior cruciate ligament (ACL) injury. Methods: We captured 254 varsity athletes, using the Kinect V2 and a smartphone application utilizing Google's M ...

Article GUID: 38730186


Comparing a Portable Motion Analysis System against the Gold Standard for Potential Anterior Cruciate Ligament Injury Prevention and Screening

Author(s): Karatzas N; Abdelnour P; Corban JPAH; Zhao KY; Veilleux LN; Bergeron SG; Fevens T; Rivaz H; Babouras A; Martineau PA;

Knee kinematics during a drop vertical jump, measured by the Kinect V2 (Microsoft, Redmond, WA, USA), have been shown to be associated with an increased risk of non-contact anterior cruciate ligament injury. The accuracy and reliability of the Microsoft Kinect V2 has yet to be assessed specifical ...

Article GUID: 38544237


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