Author(s): Sun B; Yang JG; Wang Z; Wang Z; Feng W; Li X; Liu SN; Li J; Zhu YQ; Zhang P; Wang W;

Background: The distribution of the m6A methylation modification on the transcriptome is highly regionally selective and is mainly concentrated in abnormally long exons and stop codons. However, in-depth research on the selective mechanism of m6A methylation is still lacking. Methods: In this research, meRIP sequencing, mRNA sequencing, meRIP, luciferase ...

Article GUID: 40051055

Author(s): Yang JG; Sun B; Wang Z; Li X; Gao JH; Qian JJ; Li J; Wei WJ; Zhang P; Wang W;

Osteoporosis has a profound influence on public health. First-line bisphosphonates often cause osteonecrosis of the jaw meanwhile inhibiting osteoclasts. Therefore, it is important to develop effective treatments. The results of this study showed that the increased level of NFATc1 m6A methylation caused by zoledronic acid (ZOL), with 4249A as the function ...

Article GUID: 37957146