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Investigating Physical Exercise and Cognitive Training Effects on Cognition and Brain Health in Men and Women with Heart Failure: The ReCARDIO Trial

Author(s): Bherer L; Besnier F; Gagnon C; Vrinceanu T; Vincent T; Mohammadi H; Gauthier C; Duquesne C; Blanchette CA; Bérubé B; Said SN; Iglesies-Grau J; L' Allier P; Boulet J; Nigam A; Dionne V; Benhalima H; Dubé MP; Duchesne S; Belleville ...

Cognitive impairment can affect up to 50% of patients with chronic heart failure (CHF) and is associated with reduced treatment adherence, high mortality rates, and poor quality of life. Nonpharmacologic strategies, including cognitive intervention and physical exercise training, may help enhan ...

Article GUID: 42327429


Prehabilitation in degenerative cervical myelopathy: An underexplored opportunity to optimize outcomes

Author(s): Fortin M; Chauhan RV; Boerger TF; Montpetit C; Kobaisi A; Lantz JM; Kumar V; Plener J; Demetriades AK; Wood L; Dastagir O; Treanor C; Toumbas G; Ammendolia C; Wilson N; Anderson DB;

Article GUID: 42253823


Prise en charge de la multimorbidité cœur-cerveau : un guide de pratique clinique

Author(s): Edwards JD; Li Z; McFarlane P; Rabi DM; Gilbert J; Bajaj HS; MacIntosh BJ; Bittman J; Feldman RD; Dresser G; Terenzi K; Swartz R; Gabor J; Pearson GJ; Selby P; Wharton S; Warburton DER; Pakhalé S; Styra R; Baker B; Tu K; Hawkins M; Sto ...

id="fra-abstract"> Contexte: Les maladies du cœur et les maladies du cerveau partagent divers facteurs de risque et elles coexistent souvent; pourtant, les guides de pratique clinique en cardiologie et en neurologie sont le plus souvent produits en silos disciplinaires. Élaboré par un ...

Article GUID: 42185004


Isatin-pyridine oxime hybrids as potential reactivators of A-242-inhibited acetylcholinesterase

Author(s): Pinto AMV; Bhattacharyya D; da Silva MCJ; Kitagawa DAS; Dos Santos MC; Cavalcante SFA; Islam ST; LaPlante SR; Forgione P; Diz JSF; França TCC;

Three new isatin-pyridine-2-oxime hybrids (AM01-03) were synthesized and experimentally evaluated as reactivators of acetylcholinesterase (AChE) inhibited by a surrogate of the nerve agent A-242, in comparison with their 4-oxime isomers previously reported by our research group. Furthermore, th ...

Article GUID: 42171685


em Trans /em -eQTLs reveal the architecture of human gene regulatory networks

Author(s): Warmerdam CAR; Westra HJ; van der Graaf A; Bonder MJ; Deelen P; van Lieshout T; Landman AJ; Jesse M; Strober BJ; Boltz T; Lapinska S; Nagpal S; Xie M; Tay D; Kirsten H; Naeem H; Raghavan V; Farzeen A; Teumer A; Favé MJ; Persyn E; Tokol ...

Many non-coding variants influence complex traits and diseases through gene regulation, yet the mechanisms linking these variants to downstream biology remain poorly understood. Here, we present eQTLGen Phase 2, a comprehensive genome-wide analysis of gene expression quantitative trait loci (eQ ...

Article GUID: 42051578


Microwave Synthesis of CuNi/TiO sub 2 /sub Nanotubes for Enhanced Photocatalytic H sub 2 /sub Generation

Author(s): Yimbila S; Perdomo C; Vo DK; Pérez CJV; Onwubiko V; Nguyen NT;

Microwave-assisted synthesis offers several advantages over conventional methods, including shorter reaction times and more efficient heating in systems containing polar solvents such as water or ethanol. These features can be exploited to prepare and modify active photocatalysts for H2-production reactions, allowing precise tuning of composition and fi ...

Article GUID: 42059823


Microbial fuel cell (MFC)-based biosensor for real-time detection of heavy metals and BTEX contaminants in water

Author(s): Baik JH; Hwang JH; Ryu H; Gomez-Alvarez V; Kim KT; Hyoung Lee W;

This study evaluates a mixed-culture microbial fuel cell (MFC) as a rapid, real-time biosensor for detecting water toxicity caused by heavy metals and benzene, toluene, ethylbenzene, and xylene (BTEX) compounds. A dual-chamber MFC (200 mL) equipped with carbon fiber electrodes was operated with an electroactive biofilm on the anode, and toxicity respons ...

Article GUID: 41962434


Conversation cards for pregnancy: a protocol for a multi-method study

Author(s): Alberga AS; Forouhar V; Lurye V; Adamo KB; Avery S; Ball GDC; Farnesi BC; Gaudet L; Nagpal TS; Piccinini-Vallis H; Ramos Salas X; Rhodes RE; Vallis M; Cook J; Graham TM; Stanworth-Belleville K; Cohen TR;

Background: Conversations regarding health behaviours, mental health, and socioeconomic contexts are recommended during prenatal visits to optimize maternal and fetal health outcomes. This study was designed to develop and evaluate the acceptability of a clinical dialogue tool called Conversati ...

Article GUID: 41964085


How Do Immigration Policies Affect Voter Support for Low-Skilled Immigrants? Evidence from a Survey Experiment

Author(s): Hopkins V; Lawlor A; Paquet M;

Countries depend on both high- and low-skilled immigration to meet economic needs. But most voters prefer high-skilled immigrants, despite the fact that multiple economic sectors structurally depend on low-skilled immigrants. In this paper, we examine voter preferences toward low-skilled immigrants as one barrier to effective immigration policy, even in ...

Article GUID: 41938359


Alternative reproductive strategies explain asymmetries in reproductive isolation and reinforcement in two Ischnura damselfly species

Author(s): Ordaz-Morales JE; Juárez-Jiménez AL; Stand-Pérez M; Arce-Valdés LR; Ballén-Guapacha AV; Chávez-Ríos JR; Boasso O; Rajan N; Cordero-Rivera A; Sánchez-Guillén RA;

Theoretical and empirical studies of reinforcement have advanced our understanding of speciation, yet its role in polymorphic species remains understudied. Because morphs differ in behavior, morphology, and reproductive strategies, reinforcement may act unevenly among them, generating asymmetri ...

Article GUID: 41933171


Management of brain-heart multimorbidity: a clinical practice guideline

Author(s): Edwards JD; Li Z; McFarlane P; Rabi DM; Gilbert J; Bajaj HS; MacIntosh BJ; Bittman J; Feldman RD; Dresser G; Terenzi K; Swartz R; Gabor J; Pearson GJ; Selby P; Wharton S; Warburton DER; Pakhalé S; Styra R; Baker B; Tu K; Hawkins M; Sto ...

Background: Although brain and heart conditions share overlapping risk factors and commonly co-occur, current cardiac and neurologic clinical guidelines are typically produced within specialty silos. The objective of this guideline from a Canadian Cardiovascular Harmonized National Guideline En ...

Article GUID: 41912243


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