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Regioselective Stepwise Synthesis of Unsymmetrical 1,2,5-Triarylpyrroles via Palladium-Catalyzed Decarboxylative Cross-Coupling and C-H Arylation

Author(s): Buonomano C; Patterson S; Ngou JS; Messina C; Taylor S; Bilodeau F; Forgione P;

Pyrrole derivatives are natural organic molecules that are important to the pharmaceutical industry due to their occurrence in nature and their use in a wide range of medical applications. In general, non-symmetric, 1,2,5-triaryl-substituted pyrroles are prepared either by Paal-Knorr condensation or cycloaddition that present synthetic challenges particul ...

Article GUID: 41900086


Synthesis and Characterization of CNC/CNF/rGO Composite Films for Advanced Functional Applications

Author(s): Ramezani G; Stiharu I; van de Ven TGM; Ramezani H; Nerguizian V;

Developing advanced functional materials requires the synergistic integration of nanoscale reinforcements with tailored properties. In this work, composite films of cellulose nanocrystals (CNCs), cellulose nanofibrils (CNFs), and reduced graphene oxide (rGO) were synthesized using a combination of solution casting, high shear homogenization, vacuum filtra ...

Article GUID: 41900273


Evaluation and Utilization of Aged Bacteria in MICP Technology

Author(s): Fukue M; Lechowicz Z; Mulligan CN; Takeuchi S; Takeuchi H;

As a response to aging of cultured urease-producing microorganisms, the blending method was examined to obtain the required carbonate production amount using the apparent viability (Rcv) based on previous research. As a result, a significantly higher carbonate content than the amount of CaCl2 2H2O used was produced. Since this trend has been obtained in p ...

Article GUID: 41900613


Development of an evaporation-driven sampling system for the in situ long-term monitoring of heavy metals in surface water

Author(s): Li X; Ma H; Shi S; Tian X; Nie L; Han X; Sun J; Chen Z; Li J; Chen K;

Non-electrically driven samplers, commonly known as passive samplers, are widely used in surface water monitoring to determine the Time-Weighted Average Concentration (CTWA) of contaminants. In this study, we developed an evaporation-driven sampling system and methodology, comprising an Evaporation-Driven Sampler (EDS) for sampling and its standard versio ...

Article GUID: 41886856


Gambling and the COVID-19 pandemic in the province of Quebec (Canada): results from an online cross-sectional survey of people who had gambled within the last 12 months

Author(s): Brodeur M; Fortier MÈ; Carrier N; Audette-Chapdelaine S; Auger AM; Savard AC; Kairouz S;

Objectives: This article presents the quantitative phase of a two-phase mixed methods study. The main objective of this article is to examine how the COVID-19 pandemic affected adult gamblers' gambling behaviours and mental health in Quebec. Design: A cross-sectional online survey was used to collect data. Setting: Quebec (Canada). Participants: A ...

Article GUID: 41887629


Individual differences in empathy-related responses in early childhood: A person-centred approach

Author(s): Bullinger J; Christner N; Urian R; Kellermann CM; Beaulieu S; Steinbeis N; Dunfield KA; Paulus M;

Empathy is vital for social development in early childhood. This study investigates the empathy-related behaviours of 362 German and Canadian children (49.72% girls) aged 3 to 6 years (M = 60.65 months; SD = 11.43 months), focusing on responses to emotional distress. Using latent profile analysis ...

Article GUID: 41888065


Perceived Partner Responsiveness is Associated with Longitudinal Changes in Circulating Inflammatory Biomarkers Among Caregiving Mothers in Midlife

Author(s): Gouin JP; Sánchez-Carro Y; Cruz IP; MacNeil S;

Positive social relationships are linked to better health outcomes. Beyond global evaluations of relationship quality, little is known about how specific interpersonal processes may influence biological pathways promoting optimal health outcomes. Perceived partner responsiveness (PPR) is an interpersonal process through which an individual comes to believ ...

Article GUID: 41876038


Nightly variations in sleep quality and next-day cognitive performance: an in-home study in healthy older adults

Author(s): Brooks M; El Chami R; Jourde HR; Savard MA; Coffey EBJ;

Introduction: Sleep quality is often thought to be a key determinant of cognitive performance, particularly in older adults who experience age-related changes in sleep architecture. However, the extent to which nightly variations in sleep quality impact next-day cognitive performance remains unclear-in part because it has only recently become practical to ...

Article GUID: 41878310


Development and validation of the EDIT weight stigma reduction checklist

Author(s): de la Piedad Garcia X; Cooper K; Jardine IR; Alberga AS; Darling KE; Hill AJ; Howes EM; Vidmar AP; Yourell J; Lister NB; Jebeile H;

Background: Weight stigma and weight discrimination refer to the negative attitudes and behaviours towards people with higher weight, because of their body size. Experiences of weight stigma in healthcare settings and within weight management interventions contribute to poor psychological and phy ...

Article GUID: 41876679


Strengthening and Targeted Rehabilitation for Optimal Neuromuscular Gains for chronic BACK pain (STRONG-BACK): protocol for a randomised controlled trial in participants with primary nociceptive pain drivers

Author(s): Fortin M; Rosenstein B; Bertrand C; Vaillancourt N; Wright A; Montpetit C; Macedo L; Elliott J; Cook CE; Tousignant-Laflamme Y; Ma J; Pagé MG; Dover G; Dang-Vu TT; Weber MH;

Introduction: Exercise therapy is the most recommended treatment for chronic low back pain (LBP), with evidence supporting modest effects, likely due to the heterogeneity of patient presentations. Evidence suggests that matching individuals to the most appropriate exercise type could improve outc ...

Article GUID: 41876162


Cross-modal synchrony between music and visual motion modulates vection, urge to move, and comfort in VR

Author(s): Van Kerrebroeck B; Spiech C; Penhune V; Wanderley MM;

Sensorimotor entrainment, the spontaneous alignment of movement with external rhythms, plays a key role in how we experience music and motion. In this study, we introduce a novel method combining musical stimuli, vection, and visually induced motion sickness (VIMS) in virtual reality (VR) to investigate how cross-modal rhythmic stimulation shapes self-mot ...

Article GUID: 41867666


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