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Advances in Drug Design and Development for Human Therapeutics Using Artificial Intelligence-II

Author(s): Wei D; Peslherbe GH; Selvaraj G; Wang Y;

Building on our 2021-2022 Special Issue, "Advances in Drug Design and Development for Human Therapeutics Using Artificial Intelligence [...].

Article GUID: 38136606


At the mercy of myself: A thematic analysis of beliefs about losing control

Author(s): Kelly-Turner K; Radomsky AS;

Purpose: Concerns about the likelihood, consequences, and meaning of losing control are commonplace across anxiety-related disorders. However, several experimental studies have suggested that individuals without a diagnosis of a mental disorder also believe that they can and will lose control under the right circumstances. Understanding the range of belie ...

Article GUID: 38131416


Weighty words: exploring terminology about weight among samples of physicians, obesity specialists, and the general public

Author(s): Wilson OWA; Nutter S; Russell-Mayhew S; Ellard JH; Alberga AS; MacInnis CC;

Background: The words used to refer to weight and individuals with large bodies can be used to reinforce weight stigma. Given that most previous research has examined preferred terminology within homogenous groups, this research sought to examine terminology preferences across populations. Methods: This paper reports on data gathered with the general pub ...

Article GUID: 38131299


Learning from opioid withdrawal: Effects on striatal dopamine (Commentary on Ahn et al., 2023)

Author(s): Leyton M; Nikolic M;

No abstract available

Article GUID: 38129315


On-site workshop investment problem: A novel mathematical approach and solution procedure

Author(s): Moradi N; Kayvanfar V; Baldacci R;

In real-world construction sites, On-Site Workshops (OSW) are installed to accelerate construction activities and facilitate the material handling process. These temporary OSWs are cost-effective, leading to decreasing the material handling cost and project makespan, which indicates their important role as a part of a construction project. However, consid ...

Article GUID: 38125448


Decreased long-range temporal correlations in the resting-state functional magnetic resonance imaging blood-oxygen-level-dependent signal reflect motor sequence learning up to 2 weeks following training

Author(s): Jäger AP; Bailey A; Huntenburg JM; Tardif CL; Villringer A; Gauthier CJ; Nikulin V; Bazin PL; Steele CJ;

Decreased long-range temporal correlations (LRTC) in brain signals can be used to measure cognitive effort during task execution. Here, we examined how learning a motor sequence affects long-range temporal memory within resting-state functional magnetic resonance imaging signal. Using the Hurst e ...

Article GUID: 38124341


Factors associated with change in moderate or severe symptoms of anxiety and depression in community-living adults and older adults during the COVID-19 pandemic

Author(s): Vasiliadis HM; Spagnolo J; Bartram M; Fleury MJ; Gouin JP; Grenier S; Roberge P; Shen-Tu G; Vena JE; Lamoureux-Lamarche C; Wang J;

Objectives: Few are the longitudinal studies on the changes in moderate or severe symptoms of anxiety or depression (MSS-ANXDEP) from before to during the COVID-19 pandemic in Canada. The aim was to study the change in MSS-ANXDEP and associated sociodemographic, economic, psychosocial, health beh ...

Article GUID: 38117417


Effects of electron acceptors and donors on anaerobic biodegradation of PAHs in marine sediments

Author(s): Chen Q; Li Z; Chen Y; Liu M; Yang Q; Zhu B; Mu J; Feng L; Chen Z;

Polycyclic aromatic hydrocarbons (PAHs) are typical organic pollutants accumulated in the environment. PAHs' bioremediation in sediments can be promoted by adding electron acceptor (EA) and electron donor (ED). Bicarbonate and sulfate were chosen as two EAs, and acetate and lactate were selected as two EDs. Six groups of amendments were added into the ...

Article GUID: 38113802


Effect of aquatic exercise versus standard care on paraspinal and gluteal muscles morphology in individuals with chronic low back pain: a randomized controlled trial protocol

Author(s): Rosenstein B; Montpetit C; Vaillancourt N; Dover G; Khalini-Mahani N; Weiss C; Papula LA; Melek A; Fortin M;

Background: Low back pain (LBP) is one of the most disabling diseases and a major health issue. Despite the evidence of a link between paraspinal and gluteal muscle dysfunction and LBP, it is unknown whether aquatic exercises can lead to improvements in paraspinal and gluteal muscle morphology an ...

Article GUID: 38110922


New Directions in Qualitative Research at the Social Sciences Section of The Journals of Gerontology Series B

Author(s): Kate de Medeiros

No abstract available

Article GUID: 38109420


Discovery of an adjuvant that resensitizes polymyxin B-resistant bacteria

Author(s): Mahdavi M; Findlay BL;

Infections caused by antibiotic-resistant bacteria are a major threat to health, increasing mortality rates and straining health systems worldwide. Adjuvants targeted to beta-lactamase function are able to resensitize bacteria to beta-lactam antibiotics, but there is comparatively little research into the use of adjuvants against other resistance phenotyp ...

Article GUID: 38096681


Using 13C enriched acetate in isotope labelling incubation experiments: a note of caution

Author(s): Leone F; Imfeld A; Mirzaei Y; Gélinas Y;

Vapour-phase fumigation with HCl is routinely used to remove inorganic carbon in preparation for the measurement of the concentration and d13C value of organic carbon in a sample using elemental analysis coupled to an isotope ratio mass spectrometer. Acidification of the sample to be analyzed can lead to the loss of low molecular weight conjugate bases as ...

Article GUID: 38097918


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