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Droplet digital microfluidic system for screening filamentous fungi based on enzymatic activity

Author(s): Samlali K; Alves CL; Jezernik M; Shih SCC;

Fungal cell-wall-degrading enzymes have great utility in the agricultural and food industries. These cell-wall-degrading enzymes are known to have functions that can help defend against pathogenic organisms. The existing methods used to discover these enzymes are not well adapted to fungi culture and morphology, which prevents the proper evaluation of the ...

Article GUID: 36438986


Longitudinal Associations Between Relationship Quality and Depression Among Youth with Intellectual Disabilities: A Latent Change Perspective

Author(s): Dubé C; Morin AJS; Olivier E; Tóth-Király I; Tracey D; Craven RG; Maïano C;

This study investigates associations between initial levels and change in the quality of the relationships youth with intellectual disabilities (ID) share with their parents and teachers, and changes in their levels of depression over time. A sample of 395 youth with mild (48.3%) and moderate (51.7%) ID, aged between 11 and 22 (M = 15.69), were recruited ...

Article GUID: 36436145


The use of technology in the treatment of youth with eating disorders: A scoping review

Author(s): Dufour R; Novack K; Picard L; Chadi N; Booij L;

Background: Adolescence and young adulthood is a high-risk period for the development of eating disorders. In recent years, there has been an increase in use of technology-based interventions (TBIs) for the treatment of eating disorders. The objective of this study was to determine the types of technology used for eating disorder treatment in youth and th ...

Article GUID: 36434657


Demographic resilience of brook trout populations subjected to experimental size-selective harvesting

Author(s): Clarke SH; McCracken GR; Humphries S; Ruzzante DE; Grant JWA; Fraser DJ;

Sustainable management of exploited populations benefits from integrating demographic and genetic considerations into assessments, as both play a role in determining harvest yields and population persistence. This is especially important in populations subject to size-selective harvest, because size selective harvesting has the potential to result in sign ...

Article GUID: 36426123


Structural determination and anticholinesterase assay of C-glycosidic ellagitannins from Lawsonia inermis leaves: A study supported by DFT calculations and molecular docking

Author(s): Orabi MAA; Orabi EA; Abdel-Sattar ES; English AM; Hatano T; Elimam H;

An ellagitannin monomer, lythracin M (1), and a dimer, lythracin D (2), along with eight known monomers (3-10) were isolated from Lawsonia inermis (Lythraceae) leaves. Lythracin M (1) is a C-glycosidic ellagitannin with a flavogallonyl dilactone moiety that participates in the creation of a ?-lactone ring with the anomeric carbon of the glucose core. Lyth ...

Article GUID: 36423882


Defect-engineered surfaces to investigate the formation of self-assembled molecular networks

Author(s): Yu LH; Cai ZF; Verstraete L; Xia Y; Fang Y; Cuccia L; Ivasenko O; De Feyter S;

Herein we report the impact of covalent modification (grafting), inducing lateral nanoconfinement conditions, on the self-assembly of a quinonoid zwitterion derivative into self-assembled molecular networks at the liquid/solid interface. At low concentrations where the compound does not show self-assembly behaviour on bare highly oriented pyrolytic graphi ...

Article GUID: 36425498


A Systematic Review on Vaccine Hesitancy in Black Communities in Canada: Critical Issues and Research Failures

Author(s): Cénat JM; Noorishad PG; Bakombo SM; Onesi O; Mesbahi A; Darius WP; Caulley L; Yaya S; Chomienne MH; Etowa J; Venkatesh V; Dalexis RD; Pongou R; Labelle PR;

Black communities have been disproportionately impacted by Coronavirus Disease 2019 (COVID-19) in Canada, in terms of both number of infections and mortality rates. Yet, according to early studies, vaccine hesitancy appears to be higher in Black communities. The purpose of this systematic review ...

Article GUID: 36423032


Diversity is the spice of life: An overview of how cytokinesis regulation varies with cell type

Author(s): Ozugergin I; Piekny A;

Cytokinesis is required to physically cleave a cell into two daughters at the end of mitosis. Decades of research have led to a comprehensive understanding of the core cytokinesis machinery and how it is regulated in animal cells, however this knowledge was generated using single cells cultured in vitro, or in early embryos before tissues develop. This ra ...

Article GUID: 36420142


Estimation of Anthropogenic VOCs Emission Based on Volatile Chemical Products: A Canadian Perspective

Author(s): Asif Z; Chen Z; Haghighat F; Nasiri F; Dong J;

Volatile organic compounds (VOCs) in urban areas are of great interest due to their significant role in forming ground-level ozone and adverse public health effects. Emission inventories usually compile the outdoor VOCs emission sources (e.g., traffic and industrial emissions). However, considering emissions from volatile chemical products (e.g., solvents ...

Article GUID: 36416924


Cytokinetic diversity in mammalian cells is revealed by the characterization of endogenous anillin, Ect2 and RhoA

Author(s): Husser MC; Ozugergin I; Resta T; Martin VJJ; Piekny AJ;

Cytokinesis is required to physically separate the daughter cells at the end of mitosis. This crucial process requires the assembly and ingression of an actomyosin ring, which must occur with high fidelity to avoid aneuploidy and cell fate changes. Most of our knowledge of mammalian cytokinesis was generated using over-expressed transgenes in HeLa cells. ...

Article GUID: 36416720


Integrating machine learning and digital microfluidics for screening experimental conditions

Author(s): Fatemeh Ahmadi

Digital microfluidics (DMF) has the signatures of an ideal liquid handling platform - as shown through almost two decades of automated biological and chemical assays. However, in the current state of DMF, we are still limited by the number of parallel biological or chemical assays that can be performed on DMF. Here, we report a new approach that leverages ...

Article GUID: 36416045


Experiencing a significant win and its sociodemographic and motivational predictors: A comparative analysis of pure-chance gamblers from Poland and France

Author(s): Lelonek-Kuleta B; Bartczuk RP; Tovar ML; Benoit E; Costes JM;

Research on the relationship between wins and gambling behavior often focuses on winning considerably large amounts of money. It seems, however, that it is not the amount of the win, but the significance that the player assigns to the win, that exerts a decisive influence on gambling behavior. Therefore, in this study we adopted the concept of significant ...

Article GUID: 36409760


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