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Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease

Author(s): Páez A; Gillman SO; Dogaheh SB; Carnes A; Dakterzada F; Barbé F; Dang-Vu TT; Ripoll GP;

Introduction: Changes in sleep physiology can predate cognitive symptoms by decades in persons with Alzheimer's disease (AD), but it remains unclear which sleep characteristics predict cognitive and neurodegenerative changes after AD onset. Methods: Using data from a prospective cohort of mild to moderate AD (n = 60), we analyzed non-rapid eye moveme ...

Article GUID: 39878233


Is There a Need to Reassess Protein Intake Recommendations Following Metabolic Bariatric Surgery?

Author(s): Ben-Porat T; Lahav Y; Cohen TR; Bacon SL; Buch A; Moizé V; Sherf-Dagan S;

Purpose of review: Protein intake is recognized as a key nutritional factor crucial for optimizing Metabolic Bariatric Surgery (MBS) outcomes by preventing protein malnutrition, preserving fat-free mass, and inducing satiety. This paper discusses the current evidence regarding protein intake and its impact on clinical outcomes following MBS. Recent findi ...

Article GUID: 39878797


Facebook recruitment: understanding research relations Prior to data collection

Author(s): Young K; Browne K;

This article considers the multiple relations that emerge from and between Facebook commenters, as well as between commenters, researchers, and the research project during recruitment. To do so, we draw on our experiences of recruiting individuals who have concerns about or are opposed to a range of recent social and legal changes in 'post-equality ...

Article GUID: 39877298


Toward cognitive models of misophonia

Author(s): Savard MA; Coffey EBJ;

Misophonia is a disorder in which specific common sounds such as another person breathing or chewing, or the ticking of a clock, cause an atypical negative emotional response. Affected individuals may experience anger, irritability, annoyance, disgust, and anxiety, as well as physiological autonomic responses, and may find everyday environments and contex ...

Article GUID: 39874936


Intramyocellular lipid use is altered with exercise in males with childhood-onset obesity despite no differences in substrate oxidation

Author(s): Feola S; Al-Nabelsi L; Tam BT; Near J; Morais JA; Santosa S;

Objective: Compared to adulthood-onset obesity (AO), those with childhood-onset obesity (CO) are at greater risk of metabolic disease. However, the differences between these two obesity phenotypes are not clear. The aim of this study is to investigate how the age of obesity onset (CO vs. AO) affects the use of intramyocellular (IMCL) and extramyocellular ...

Article GUID: 39875595


Behavioral interventions-past, present, and future: Proceedings of the 5th International Behavioural Trials Network International Hybrid Meeting

Author(s): Bacon SL; Lavoie KL; Buckeridge D; Dietz WH; Freedland KE; Grimshaw JM; Jaworski BK; Laur C; Marques MM; Michie S; Powell LH; Rothman AJ; Whitmarsh L;

No abstract available

Article GUID: 39873378


Contribution of Coal Tar Sources to Polycyclic Aromatic Compounds and Associated Ecological Risk in Lake Ontario Sediments: Inference from a Novel Marker

Author(s): Zhang X; Bowman DT; Diamond ML; Helm P; Jobst KJ; Hao C; Kleywegt S; Zhang ZF; Marvin C; Zhang X;

Coal tar-related products as a source of polycyclic aromatic compounds (PACs) are particularly concerning due to high PAC concentrations and inadequate source management. Benzo[b]carbazole, a benzocarbazole isomer exclusively found in coal tar-derived products, acts as an ideal marker to distingu ...

Article GUID: 39870568


Water Quality and Land Use Shape Bacterial Communities Across 621 Canadian Lakes

Author(s): Onana VE; Beisner BE; Walsh DA;

Human activities such as agriculture and urban development are linked to water quality degradation. Canada represents a large and heterogeneous landscape of freshwater lakes, where variations in climate, geography and geology interact with land cover alteration to influence water quality differently across regions. In this study, we investigated the influ ...

Article GUID: 39868666


Sex differences in the metabolism of glucose and fatty acids by adipose tissue and skeletal muscle in humans

Author(s): Costa DN; Santosa S; Jensen MD;

Adult males and females have markedly different body composition, energy expenditure, and have different degrees of risk for metabolic diseases. A major aspect of metabolic regulation involves the appropriate storage and disposal of glucose and fatty acids. The use of sophisticated calorimetry, tracer, and imaging techniques have provided insight into the ...

Article GUID: 39869194


Landscapes-a lens for assessing sustainability

Author(s): Dade MC; Bonn A; Eigenbrod F; Felipe-Lucia MR; Fisher B; Goldstein B; Holland RA; Hopping KA; Lavorel S; Lede Polain Waroux Y; MacDonald GK; Mandle L; Metzger JP; Pascual U; Rieb JT; Vallet A; Wells GJ; Ziter CD; Bennett EM; Robinson BE;

Context: There are urgent calls to transition society to more sustainable trajectories, at scales ranging from local to global. Landscape sustainability (LS), or the capacity for landscapes to provide equitable access to ecosystem services essential for human wellbeing for both current and future ...

Article GUID: 39867571


Development of a Prandtl-Ishlinskii hysteresis model for a large capacity magnetorheological fluid damper

Author(s): Vatandoost H; Abdalaziz M; Sedaghati R; Rakheja S;

Magnetorheological (MR) fluid (MRF) dampers, serving as fail-safe semi-active devices, exhibit nonlinear hysteresis characteristics, emphasizing the necessity for accurate modeling to formulate effective control strategies in smart systems. This paper introduces a novel stop operator-based Prandtl-Ishlinskii (PI) model, featuring a reduced parameter set ( ...

Article GUID: 39867636


Ingestion of polyethylene microplastics impacts cichlid behaviour despite having low retention time

Author(s): Felismino MEL; Chevallier Rufigny S; Gonzalez-Fleurant SE; Brown GE;

Microplastics, particles between 0.001 and 5 mm in diameter, are ubiquitous in the environment and their consumption by aquatic organisms is known to lead to a variety of adverse effects. However, studies on the effects of microplastics on prey fish have not shown consistent trends, with results varying across species and plastic type used. Here, we manip ...

Article GUID: 39862685


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