Author(s): Schebb NH; Kampschulte N; Hagn G; Plitzko K; Meckelmann SW; Ghosh S; Joshi R; Kuligowski J; Vuckovic D; Botana MT; Sánchez-Illana Á; Zandkarimi F; Das A; Yang J; Schmidt L; Checa A; Roche HM; Armando AM; Edin ML; Lih FB; Aristizabal-Hena ...

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendat ...

Article GUID: 40392938

Author(s): Gumuchian ST; Boyle A; Kennedy G; Wong SF; Ellenbogen MA;

Despite high recurrence rates in major depressive disorder (MDD), little is known about the factors influencing recurrence. Understanding the changes that occur between major depressive episodes (MDEs) is imperative. It is possible that being fearful of experiencing another MDE may lead to cognitive and behavioural changes that increase MDD recurrence ris ...

Article GUID: 40391691

Author(s): Little SR; Rahbari N; Hajiaghayi M; Gholizadeh F; Cloarec-Ung FM; Phillips J; Sinha H; Hirukawa A; Knapp DJHF; Darlington PJ; Shih SCC;

Genetically engineering human immune cells has been shown to be an effective approach for developing novel cellular therapies to treat a wide range of diseases. To expand the scope of these cellular therapies while solving persistent challenges, extensive research and development is still require ...

Article GUID: 40390294

Author(s): Comeau P; Leite ML; Manso A;

The main objective of this study was to develop a natural curcumin-loaded varnish that responds to blue light in an antimicrobial photodynamic therapy-based approach with photoelimination of targeted cells. Fluoride-free curcumin-loaded varnish (CUR-V) consisting of gum rosin (80 wt%) and ethanol (20 wt%) was loaded with 0, 0.25, and 10.0 wt% curcumin and ...

Article GUID: 40387395

Author(s): Zajac Z; Helfield B; Williams R; Sheeran P; Tremblay-Darveau C; Yoo K; Burns PN;

Objectives: The development of low boiling point liquid droplets as phase-change contrast agents allows for the local creation of microbubbles at a point of interest in vivo. Although there are many possible applications, few investigations have used selectively created microbubble boluses to measure volumetric flowrate. In this study, the flow ratio betw ...

Article GUID: 40387284

Author(s): Wang X; Du Z; Song Z; Liu M; He P; Feng L; Chen Z; Chen Q;

This study investigated the oil pollution remediation ability of konjac glucomannan (KGM) aerogel immobilized Chlorella vulgaris LH-1 (C. vulgaris). The KGM aerogel exhibited a high porosity of 86.83 %, and with the change of crude oil concentration (1-10 g/L), the crude oil adsorption efficiency of KGM aerogel was up to 18.75 %. The KGM aerogel carrier e ...

Article GUID: 40381443

Author(s): Forouhar V; Edache IY; Alberga AS;

The majority of Canadian adults are not meeting the recommended physical activity and sedentary behaviour guidelines. Previous studies have highlighted experiences of weight bias as a potential barrier to physical activity and an enabler of sedentary behaviours. Few studies have examined whether endorsing or internalizing weight bias is associated with th ...

Article GUID: 40374859

Author(s): Delaire É; Vincent T; Cai Z; Machado A; Hugueville L; Schwartz D; Tadel F; Cassani R; Bherer L; Lina JM; Pélégrini-Issac M; Grova C;

Significance: Understanding the brain's complex functions requires multimodal approaches that combine data from various neuroimaging techniques. Functional near-infrared spectroscopy (fNIRS) offers valuable insights into hemodynamic responses, complementing other modalities such as electroenc ...

Article GUID: 40375973

Author(s): Pinto SM; Cheung JPY; Samartzis D; Karppinen J; Zheng YP; Pang MYC; Fortin M; Wong AYL;

Background: Although individuals with chronic low back pain (CLBP) show increased fatty infiltration in the lumbar multifidus muscle (LMM), it remains unclear whether LMM changes are related to clinical outcomes (such as pain and disability) after considering confounders (spinal phenotypes, fear-avoidance beliefs [FABs] and insomnia). This study examined: ...

Article GUID: 40376565

Author(s): Johannessen C; Saini A; Zhang X; Harner T;

Tire-derived chemicals (TDCs) are shown to be elevated in urban environments. In this study, we analyzed 6PPD-quinone, 2,2,4-trimethyl-1,2-dihydroquinoline (TMQ), hexa(methoxy)methylmelamine (HMMM), as well as selected benzothiazoles and benzotriazoles, in different urban source-sectors. The chemical analyses were conducted on archived extracts of polyure ...

Article GUID: 40370926

Author(s): Wu KY; Dave A; Nirwal GK; Giunta M; Nguyen VDH; Tran SD;

Exosomes, a subset of extracellular vesicles, have emerged as potential therapeutic agents in ophthalmology due to their ability to modulate immune responses, facilitate cellular communication, and promote tissue repair. This chapter explores the potential applications of exosome-based therapies in corneal and anterior segment disorders, retinal diseases, ...

Article GUID: 40360847

Author(s): Klages KL; James RN; Kain ZN; Phipps S; Alberts NM; Fortier MA;

Introduction: Cancer pain remains a significant burden among children with cancer, and many patients experience pain starting around the time of diagnosis and throughout the course of treatment. A biopsychosocial treatment approach has been recommended to improve pain management in this population; however, specific psychosocial factors that contribute to ...

Article GUID: 40365620