Author(s): Diep J; Chen E; Lui JHL;

Background: Youths with disruptive behaviours (DB) and callous-unemotional (CU) traits experience significant impairments and impose substantial costs on families and society. Treatment outcome studies of current DB treatments highlight the need for tailored treatments. Identifying priority treatment targets that integrate empirical evidence with stakeh ...

Article GUID: 42351288

Author(s): Bherer L; Besnier F; Gagnon C; Vrinceanu T; Vincent T; Mohammadi H; Gauthier C; Duquesne C; Blanchette CA; Bérubé B; Said SN; Iglesies-Grau J; L' Allier P; Boulet J; Nigam A; Dionne V; Benhalima H; Dubé MP; Duchesne S; Belleville ...

Cognitive impairment can affect up to 50% of patients with chronic heart failure (CHF) and is associated with reduced treatment adherence, high mortality rates, and poor quality of life. Nonpharmacologic strategies, including cognitive intervention and physical exercise training, may help enhan ...

Article GUID: 42327429

Author(s): Petrossian G; Diouri Y; Xu B; Ebrahimi S; Pande A; Miquet-Westphal F; Xu H; Cicoira F;

Soft, conductive materials that simultaneously offer mechanical compliance, electrical conductivity, recyclability, and scalable manufacturing remain difficult to achieve. Here, we introduce recyclable, 3D-printable PEDOT:PSS syntactic foams based on polymer microspheres coated in situ, enabling precise control over porosity, mechanical properties, and ...

Article GUID: 42310993

Author(s): Rasoulivalajoozi M; Farhoudi M;

Purpose: Wheelchairs should support not only safe and intuitive navigation but also positive social presence without reinforcing disability-related stereotypes. This study introduces a user-centred external communication framework (ECF) to guide the design of wheelchair external human-machine interfaces and their perceptual dimensions.Materials and meth ...

Article GUID: 42300838

Author(s): David LeRue

This practitioner reflection examines how painting in plein-air-meaning outdoors from life-inspired multimodal fieldnotes that became the node between research, teaching, and place. This work was conducted during a 4-year, community-engaged art education study where the community art classroom was employed to develop participatory arts-based research me ...

Article GUID: 42273064

Author(s): Perrault AA; Cross NE; Dang Vu TT; Schwartz S; Bayer L;

Specific brain oscillations can be manipulated during sleep to improve sleep quality and memory performance. We previously demonstrated that continuous rocking stimulation (0.25 Hz, lateral movement) applied to good sleepers during sleep enhanced stable deep sleep, boosted NREM oscillations (spindles and slow waves) and memory consolidation. Here, we in ...

Article GUID: 42268039

Author(s): Calvano A; Xiao Y; Steidel K; Loehrer PA; Ruppert-Junck MC; Nimsky C; Timmermann L; Bopp MHA; Pedrosa DJ;

Purpose: Accurate segmentation of the subthalamic nucleus (STN) is paramount for optimising outcomes under deep brain stimulation (DBS) in Parkinson's disease (PD). Clinically available tools like Brainlab Elements (BL-E) enable automated segmentations for surgical planning, yet their spati ...

Article GUID: 42225900

Author(s): Clayton EJ; Smith-Uffen M; Tribble TW; Duennwald ML; Kohalmi SE;

Background: Phenylalanine is an essential aromatic amino acid that can only be synthesized de novo by microorganisms and plants. In microorganisms, phenylalanine is synthesized through the prephenate pathway, requiring the activity of a prephenate dehydratase (PDT). In plants, phenylalanine is synthesized instead mostly through the arogenate pathway, re ...

Article GUID: 42204708

Author(s): Warmerdam CAR; Westra HJ; van der Graaf A; Bonder MJ; Deelen P; van Lieshout T; Landman AJ; Jesse M; Strober BJ; Boltz T; Lapinska S; Nagpal S; Xie M; Tay D; Kirsten H; Naeem H; Raghavan V; Farzeen A; Teumer A; Favé MJ; Persyn E; Tokol ...

Many non-coding variants influence complex traits and diseases through gene regulation, yet the mechanisms linking these variants to downstream biology remain poorly understood. Here, we present eQTLGen Phase 2, a comprehensive genome-wide analysis of gene expression quantitative trait loci (eQ ...

Article GUID: 42051578

Author(s): Doucet C; Gagnon IJ; Beaulieu C; Grilli L; Teel EF;

Objective: To determine if physiotherapy outcomes differ in children with concussion treated in-clinic versus virtually. Methods: Licensed physiotherapists assessed and treated 23 children with concussion using telehealth delivery during COVID-19. These patients were matched to children assessed and treated in-clinic before (n = 23) and during (n = 23) ...

Article GUID: 42095598

Author(s): Rosenstein B; Bergevin M; Bobeuf F; Bherer L; Pageaux B; Roy M; Fortin M;

Background: Multimodal exercise programs do not specifically target lumbar paraspinal musculature, but incorporate aspects of different exercises to have an overall benefit. Objective: To investigate the effect of a multimodal exercise program on paraspinal muscle volume and composition, and patient outcomes in individuals with chronic low back pain (C ...

Article GUID: 42093855