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Multilingualism and cognitive reserve in older adults with, or at risk for, Alzheimer s disease: Evidence from resting-state functional connectivity

Author(s): Coulter K; Dash T; Best T; Grant N; Ansaldo AI; Phillips NA;

Speaking more than one language is hypothesized to lead to greater brain resilience in aging and Alzheimer's disease, resulting in a delay in the symptom onset of Alzheimer's disease. While previous research has used structural neuroimaging measures to explore the neural underpinnings of this protective effect, few studies have used functional b ...

Article GUID: 42208339


Investigating substrate specificity in arogenate versus prephenate dehydratases

Author(s): Clayton EJ; Smith-Uffen M; Tribble TW; Duennwald ML; Kohalmi SE;

Background: Phenylalanine is an essential aromatic amino acid that can only be synthesized de novo by microorganisms and plants. In microorganisms, phenylalanine is synthesized through the prephenate pathway, requiring the activity of a prephenate dehydratase (PDT). In plants, phenylalanine is synthesized instead mostly through the arogenate pathway, re ...

Article GUID: 42204708


Atmospheric aging of tire rubber antioxidants forms complex mixtures that trigger inflammation in human macrophages

Author(s): Peng C; Liggio J; Moussa SG; Tang Y; Johannessen C; Zhang X; Zhang Z; Li L; Harner T; Saini A; Hung H; Wentzell J; Wheeler MJ; Dabek-Zlotorzynska E; Yassine M; Liu Q; Tang M; Friel-Bartlett Z; Abdul-Sater AA;

Antioxidants added to tires to prevent degradation have recently been recognized as emerging environmental contaminants. While their acute aquatic toxicity has raised concern, these compounds are also emitted to the atmosphere and can be associated with particulate matter (PM). On PM they can r ...

Article GUID: 42191547


Bilingual Families Align Their Languages During Naturalistic Interactions: Evidence from Two Bilingual Communities

Author(s): Fibla L; Kosie JE; Tsui RK; Potter CE; Lew-Williams C; Byers-Heinlein K;

Bilingual children learn their languages through rich interactions with caregivers within dynamic family contexts. However, little is known about how families align their two languages to support bilingual acquisition and how this varies across bilingual communities. This study examines language choice alignment across two communities: French-English fa ...

Article GUID: 42193667


Practices to Reduce Stigma and Discrimination Towards Older Transitional Housing Clients

Author(s): Canham SL; Richardson LR; Aaenson-Fletcher J; Weldrick R; Walsh CA;

Homelessness remains an enduring social issue, in part, due to the stigmatization of and discrimination toward people experiencing homelessness, known as homeism. Despite extant research on the topic, little is known about how homeism, enacted through stigmatization and discrimination, may occur within transitional housing programs or among older people ...

Article GUID: 42184413


Enhanced Lower Limb Strength and Dynamic Balance Among Older Canadian Women Following 12-Weeks of Online Ballet-Modern Dance Classes Combined with Blood Flow Restriction

Author(s): Chen EH; Saminathar AJ; Roberts M; Bergdahl A;

Introduction: Falls are a leading cause of hospitalization among older women. While dance classes have gained popularity to reduce the risk of falls, in-person classes may be inaccessible. Online classes provide feasible solutions, but are limited by the lower intensity required by the virtual environment. Blood flow restriction (BFR) provides a safe wa ...

Article GUID: 42132210


Artificial intelligence for marine oil spill management: Recent advances and future directions

Author(s): Wang Z; Huang Y; Zhang G; Wang Z; Chen Z; Mulligan CN; Li SS; Elektorowicz M; Li B; Lee K; An C;

Marine oil spills are one of the most severe anthropogenic threats to oceanic ecosystems, coastal communities, and global economic stability. While traditional monitoring and response approaches have played a foundational role in oil spill management, their effectiveness is often constrained by ...

Article GUID: 42119407


Sex-specific anxiety and depression multi-trajectories and associated risk factors in the Canadian Partnership for Tomorrow s Health longitudinal study

Author(s): Kapasa RL; Grenon C; Berbiche D; Gouin JP; Vena JE; Vasiliadis HM;

Aims: This study identified sex-specific multi-trajectories of anxiety and depression symptoms among Canadians before and during the COVID-19 pandemic, and associated factors according to a public mental health framework for the surveillance of mental health. Methods: Data from 15,021 participants in the Canadian Partnership for Tomorrow's Health c ...

Article GUID: 42107659


Age-Related Low Frequency Amplitude Differences in Resting-State Blood Oxygenation Level-Dependent Signal in the Cerebellum

Author(s): Korte JA; Steele CJ; Joiner WM; Fan AP;

There is a growing interest to study cerebellar contributions to aging outside of traditional sensory processing and motor tasks. While cerebellar aging analyses typically utilize functional connectivity (FC) to study functional differences with age, this study aimed to identify a marker of healthy aging based on resting state blood oxygenation level de ...

Article GUID: 42108695


The effect of a multimodal exercise program on paraspinal muscle morphology and clinical outcomes in chronic low back pain

Author(s): Rosenstein B; Bergevin M; Bobeuf F; Bherer L; Pageaux B; Roy M; Fortin M;

Background: Multimodal exercise programs do not specifically target lumbar paraspinal musculature, but incorporate aspects of different exercises to have an overall benefit. Objective: To investigate the effect of a multimodal exercise program on paraspinal muscle volume and composition, and patient outcomes in individuals with chronic low back pain (C ...

Article GUID: 42093855


Computational optical streak microscopy of megahertz acoustic microbubble dynamics

Author(s): Marquez M; Lai Y; Liu M; Memari E; Helfield B; Liang J;

Real-time dynamic imaging of microbubbles is crucial for understanding their microscale biophysical interactions and advancing ultrasound therapy. Despite progress in time-resolved optical imaging, existing techniques still face trade-offs between acquisition speed, spatial resolution, affordability, and system complexity. Here, we introduce compressed ...

Article GUID: 42078858


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