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Sex-specific anxiety and depression multi-trajectories and associated risk factors in the Canadian Partnership for Tomorrow s Health longitudinal study

Author(s): Kapasa RL; Grenon C; Berbiche D; Gouin JP; Vena JE; Vasiliadis HM;

Aims: This study identified sex-specific multi-trajectories of anxiety and depression symptoms among Canadians before and during the COVID-19 pandemic, and associated factors according to a public mental health framework for the surveillance of mental health. Methods: Data from 15,021 participants in the Canadian Partnership for Tomorrow's Health coh ...

Article GUID: 42107659


Age-Related Low Frequency Amplitude Differences in Resting-State Blood Oxygenation Level-Dependent Signal in the Cerebellum

Author(s): Korte JA; Steele CJ; Joiner WM; Fan AP;

There is a growing interest to study cerebellar contributions to aging outside of traditional sensory processing and motor tasks. While cerebellar aging analyses typically utilize functional connectivity (FC) to study functional differences with age, this study aimed to identify a marker of healthy aging based on resting state blood oxygenation level depe ...

Article GUID: 42108695


The effect of a multimodal exercise program on paraspinal muscle morphology and clinical outcomes in chronic low back pain

Author(s): Rosenstein B; Bergevin M; Bobeuf F; Bherer L; Pageaux B; Roy M; Fortin M;

Background: Multimodal exercise programs do not specifically target lumbar paraspinal musculature, but incorporate aspects of different exercises to have an overall benefit. Objective: To investigate the effect of a multimodal exercise program on paraspinal muscle volume and composition, and patient outcomes in individuals with chronic low back pain (CLB ...

Article GUID: 42093855


Computational optical streak microscopy of megahertz acoustic microbubble dynamics

Author(s): Marquez M; Lai Y; Liu M; Memari E; Helfield B; Liang J;

Real-time dynamic imaging of microbubbles is crucial for understanding their microscale biophysical interactions and advancing ultrasound therapy. Despite progress in time-resolved optical imaging, existing techniques still face trade-offs between acquisition speed, spatial resolution, affordability, and system complexity. Here, we introduce compressed op ...

Article GUID: 42078858


Characterization of the Biosurfactant Produced by Indigenous Bacteria from Mature Fine Tailings

Author(s): Shojaei S; Mulligan CN;

Biosurfactants offer a green, sustainable approach to many environmental bioremediations, especially for oil contamination. In this study, the aim is to evaluate the effectiveness of biosurfactants in accelerating hydrocarbon removal from mature fine tailings under anaerobic conditions. The bacteria were isolated from mature fine tailings and tested for b ...

Article GUID: 42072246


A Functional Shape Framework for the Detection of Multiple Sclerosis Using Optical Coherence Tomography Images

Author(s): Tahvilian H; Kafieh R; Ashtari F; Swamy MNS; Ahmad MO;

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease. Optical coherence tomography (OCT) is a non-invasive imaging technique of the retina. The thickness of the ganglion cell-inner plexiform layer (GCIPL) obtained from an OCT image is a valuable biomarker for monitoring MS. Since the functional shape (F-shape)-based technique has prove ...

Article GUID: 42076512


Intraperitoneal Administration of Cardiolipin Enhances Mitochondrial Respiration in Skeletal Muscle of Male Mice

Author(s): Laplante A; Bergdahl A;

Purpose: Cardiolipin is a phospholipid located in the inner mitochondrial membrane and is released following myocardial ischemia-reperfusion injury. While cardiolipin has documented effects in several tissues, its impact on skeletal muscle function and mitochondrial respiration remains unclear. The purpose of this study was to investigate the effects of e ...

Article GUID: 42046821


Intervention development to reduce sedentary behaviour among adults: a qualitative investigation using the Behaviour Change Wheel

Author(s): Harsanyi H; Slot N; Parkinson R; Morielli AR; Jeyapalan A; Holmes E; Flynn S; Campbell T; Quan H; Zeng Y; Yang J; Singh S; Vena J; Biddle S; Friedenreich CM; Yang L;

Article GUID: 42015269


Where state, market, and community meet: Village doctors and the governance of rural health in China

Author(s): Wang Z; Gao Z; Zou X; Zhang P; Ma X; Rice K; Bouey J; Liu X;

Introduction: Effective health governance is essential for ensuring accessible, equitable, efficient, and high-quality healthcare services. Yet it is often overlooked or oversimplified in health services studies in rural China. We examine the unique role of village doctors in shaping public health governance in rural China. Methods: A two-phase ethnograp ...

Article GUID: 41996877


Nature vs nurture of glucose homeostasis trajectories in children from the ALSPAC study

Author(s): Gamache I; Fagbemi K; Harnois-Leblanc S; Greenwood CMT; Henderson M; Van Hulst A; Timpson NJ; Manousaki D;

Aims/hypothesis: Dysglycaemia in youth results from complex interactions between genetic and environmental factors, yet their individual and combined contributions remain unclear. We aimed to: (1) evaluate the predictive performance of polygenic risk scores (PRSs) for glycaemic traits from childh ...

Article GUID: 41986816


Deep learning-based femoral reconstruction from intraoperative point clouds for enhanced knee arthroplasty registration

Author(s): Kafian Safari M; Mirzae M; Gheflati B; Sharifzade M; Zuhars J; Rottoo S; Rivaz H;

Purpose: Computer- and robotic-assisted technologies improve total knee arthroplasty (TKA) through intraoperative bone registration. However, limited bone exposure restricts point collection to the distal femur, omitting key geometric features and reducing registration accuracy and the surgical outcomes. Methods: We introduce a deep learning-based method ...

Article GUID: 41984365


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