Author(s): Sandkuhler SE; Youngs KS; Gottipalli O; Owlett LD; Bandora MB; Naaz A; Kim E; Wang L; Wojtovich A; Gupta V; Sacher M; Mackenzie SJ;

Mutations in the TANGO2 gene are associated with a severe neurometabolic disorder in humans, often presenting with life-threatening metabolic crisis. However, the function of TANGO2 protein remains unknown. It has recently been proposed that TANGO2 transports heme within and between cells, from a ...

Article GUID: 41504601

Author(s): Moritz A; Ezzati M; Gélinas Y;

Iron hydroxides play a key role in the preservation of organic matter in soils and sediments, yet the specificity and extent of their interactions with lignin-derived phenols-important source indicators for terrestrial organic matter-remain poorly understood in aquatic systems. In this study, we analyzed surface and downcore sediments along the terrestria ...

Article GUID: 41500137

Author(s): Wang B; Zhao H; Hu X; Shen Y; Li N;

In this study, an innovative adaptive sliding mode fault-tolerant control approach is developed for an over-actuated vertical takeoff and landing (VTOL) fixed-wing unmanned aerial vehicle (UAV) with the capability to suppress overestimation of adaptive parameters. This method is designed to effectively address model uncertainties and actuator faults witho ...

Article GUID: 41475926

Author(s): Dimri V; Davis JC; Boa Sorte Silva NC; Balbim GM; Eng JJ; Liu-Ambrose T;

Background: Common consequences of a stroke include impaired motor and cognitive function, with both being linked to increased falls and frailty. Intra-individual variability (IIV) of cognitive performance, which refers to the within-person trial-to-trial variation in reaction time during cognitive tasks, may be a useful predictor for falls in older adult ...

Article GUID: 41474479

Author(s): Zhang W; Qian H; L' Heureux J; Johns G; Koehoorn M; Woodcock S;

Cost-effectiveness guidelines recommend including productivity losses in economic evaluations conducted from a societal perspective. However, work productivity loss estimates, including absenteeism and presenteeism, are lacking for a general working population. This limits the ability of researchers and decision makers to comprehensively evaluate the incr ...

Article GUID: 41469277

Author(s): Brusseau AJP; Dumaresq-Synnott F; Morris J; Nagl AC; Ramnarine IW; Crane AL; Brown GE;

Decision-making among prey often involves balancing fitness-related activities, such as foraging and mating, with the need to avoid predation. These trade-offs may be influenced by sex, especially among sexually dimorphic species where males and females face different selection pressures. Consistent with the 'Distracted Male Hypothesis', male Trin ...

Article GUID: 41460359

Author(s): Hollett KB; Morin AJS; Carrese-Chacra E; Cohen TR; Carbonneau N; Berthiaume MM; Felice E; Gouin JP;

Socioecological models of health view romantic relationships as micro-social systems in which spouses influence one another's health-related thoughts, feelings, and behaviors. Although prior work suggests spousal interdependence in eating behaviors, the degree of interdependence may vary as a ...

Article GUID: 41448461

Author(s): Shafagh SH; Deen I; Packirisamy M;

The fabrication of conductive polymer composites (CPCs) using polydimethylsiloxane (PDMS) and poly(3,4-ethylene dioxythiophene): poly(4-styrene-sulfonate) (PEDOT: PSS) as a matrix with multi-walled carbon nanotubes (MWCNTs) and silver nanoparticles (AgNPs) as fillers was investigated to determine their potential for use in applications such as electromagn ...

Article GUID: 41424586

Author(s): Rousseau PN; Bazin PL; Steele CJ;

Article GUID: 41420671

Author(s): Joly-Smith E; Talpur MM; Allard P; Papazotos F; Potvin-Trottier L; Hilfinger A;

Characterizing and manipulating cellular behavior requires a mechanistic understanding of the causal interactions between cellular components. We present an approach to detect causal interactions between genes without the need to perturb the physiological state of cells. This approach exploits naturally occurring cell-to-cell variability which is experime ...

Article GUID: 41401079

Author(s): Kaeja M; Gajiyeva L; Iturria-Medina Y; Villringer A; Sehm B; Steele C;

Background: Stroke is a leading cause of death and disability, with proprioceptive impairments affecting up to 64% of survivors. These impairments hinder sensorimotor recovery, significantly impacting poststroke quality of life. Proprioception depends on an integrated brain network but remains underexplored due to limitations in clinical assessments, hind ...

Article GUID: 41392885