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Light-Activated Micromotors in Air Propelled by Thermal Convection

Author(s): Mena-Giraldo P; Mandl GA; Quezada-Novoa V; Garcia-Henao C; Bondon N; Hazlett MJ; Capobianco JA;

Micromotors are an attractive cutting-edge technology that exhibit controllable motion in response to chemical reactions or external stimuli. These nature-inspired materials are widely explored for use in environmental remediation, and drug delivery, other emerging applications. Until now, the mi ...

Article GUID: 40964823


Colistin heteroresistance, mechanisms, diagnostic methods, and therapeutic options: A review

Author(s): Dehbanipour R; Maleki VTZ; Ghalavand Z;

The heteroresistance phenotype refers to the presence of bacterial subpopulations with reduced antibiotic susceptibility compared with the main population. Mathematical modelling and computer simulations suggest that heteroresistance can lead to negative treatment outcomes and finally, treatment failure. Due to the low frequency and resistance level of re ...

Article GUID: 40949035


The predictive role of olfactory identification on episodic memory and mild cognitive impairment: Results from the CIMA-Q cohort

Author(s): Jobin B; Phillips NA; Frasnelli J; Boller B;

BackgroundOlfactory identification decline is a known early marker of Alzheimer's disease and is already present at the mild cognitive impairment (MCI) stage. While being linked with episodic memory, its predictive value for cognitive performance and distinguishing between clinical stages remains unclear.ObjectiveThis study examined (1) the predictive ...

Article GUID: 40944318


Assessing in silico tools for accurate pathogenicity prediction in CHD nucleosome remodelers

Author(s): Rabouhi N; Guindon S; Coleman EA; van Heesbeen HJ; Greenwood CMT; Lu T; Campeau PM;

Chromodomain Helicase DNA-binding (CHD) proteins compose a family of chromatin remodelers that play crucial roles in DNA repair and gene expression regulation, neural stem cell differentiation and chromatin integrity. Genetic variants in CHD chromatin remodelers are associated with neurodevelopmental disorders with features like autism spectrum disorder a ...

Article GUID: 40907936


Trajectories of childhood eating behaviors and their association with internalizing and externalizing symptoms in adolescence

Author(s): Dufour R; Breton É; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L;

Objective: Several studies have shown that maladaptive eating behaviors in childhood predict greater risk for eating disorders in adolescence. Whether or not maladaptive eating behaviors could represent developmental risk factors for a larger spectrum of psychopathologies is unknown. This study described longitudinal trajectories of overeating and picky e ...

Article GUID: 40883733


Global survey of secondary metabolism in em Aspergillus niger /em via activation of specific transcription factors

Author(s): Semper C; Pham TTM; Ram S; Palys S; Evdokias G; Ouedraogo JP; Moisan MC; Geoffrion N; Reid I; Di Falco M; Bailey Z; Tsang A; Benoit-Gelber I; Savchenko A;

Genomics analysis confirmed the status of filamentous fungi as a rich source of novel secondary metabolites; however, the discovery of these compounds is hampered by the cryptic nature of their biosynthetic pathways under laboratory conditions. Consequently, despite substantial research effort ov ...

Article GUID: 40852424


Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics

Author(s): Abicumaran Uthamacumaran

Advancements in AI-powered systems medicine have revolutionized biomarker discovery through emergent and explainable features. By use of complex network dynamics and graph-based machine learning, we identified critical determinants of lineage-specific plasticity across the single-cell transcriptomics of pediatric high-grade glioma (pHGGs) subtypes: IDHWT ...

Article GUID: 40848317


Development, Testing, and Application of an Enhanced Oil Spill Model for Ice-Covered Waters (OSMT-Ice) through Multiscale Field Experiments

Author(s): Yang Z; Chen Z; Lee K;

Amid growing concerns about oil spills in vulnerable Arctic and sub-Arctic regions driven by climate-induced ice retreat, this study presents the development and validation of the OSMT-ice model, an enhanced oil spill modeling system designed to predict the movement and fate of oil in ice-covered waters. The model incorporates ice-concentration-based (ICB ...

Article GUID: 40845360


Surgical hyperspectral imaging: a systematic review

Author(s): Ali HM; Xiao Y; Kersten-Oertel M;

Hyperspectral imaging (HSI) is a technique that captures and processes information across a wide spectrum of wavelengths, providing detailed spectral data for each pixel in an image to identify and analyze materials or objects. In the surgical domain, it can provide quantitative and qualitative tissue information without the need of any contrast agent, th ...

Article GUID: 40824764


An analytical framework to decode socioeconomic interplays in pesticides and fertilizer container collection patterns using land dynamics metrics

Author(s): Chowdhury R; Karimi N; Xu X; An C; Gitifar A; Ng KTW;

This study analyzes pesticide and fertilizer container collection trends across Canadian agricultural regions over a seven-year period from 2016 to 2022 through an analytical framework and proposed two land metrics. A 28.3 % decrease in the collection of small empty pesticide and fertilizer containers (EPFCs) coincides with a 41.4 % increase in the collec ...

Article GUID: 40795518


Land-use history causes differences in park nighttime cooling capacity and forest structure

Author(s): Richmond IC; Paulauskas MA; Padvaiskas E; Gonzàlez Sinisterra LC; Hutt-Taylor K; Robitaille AL; Ziter CD;

Cities are temporally dynamic ecosystems that experience continuous redevelopment over time. Urban parks, which provide critical benefits to resident wellbeing, are developed on different land-use types and contain natural elements that are susceptible to the effects of historical decision-making ...

Article GUID: 40761092


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