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MRI as a viable alternative to CT for 3D surgical planning of Cavitary bone tumors

Author(s): Chae Y; Cheers GM; Kim M; Reidler P; Klein A; Fevens T; Holzapfel BM; Mayer-Wagner S;

Cavitary bone defects, defined as a volumetric loss of native bone tissue, require accurate preoperative imaging for treatment planning. While CT (computed tomography) has traditionally been the gold standard for segmentation due to its superior resolution of cortical bone, MRI (magnetic resonance imaging) offers unique advantages, particularly in visuali ...

Article GUID: 40049253


Exon junction complexes regulate osteoclast-induced bone resorption by influencing the NFATc1 m6A distribution through the "shield effect"

Author(s): Sun B; Yang JG; Wang Z; Wang Z; Feng W; Li X; Liu SN; Li J; Zhu YQ; Zhang P; Wang W;

Background: The distribution of the m6A methylation modification on the transcriptome is highly regionally selective and is mainly concentrated in abnormally long exons and stop codons. However, in-depth research on the selective mechanism of m6A methylation is still lacking. Methods: In this research, meRIP sequencing, mRNA sequencing, meRIP, luciferase ...

Article GUID: 40051055


A person-centered examination of adverse childhood experiences and associated distal health, mental health, and behavioral outcomes in the United Arab Emirates

Author(s): Murphy A; Elbarazi I; Horen N; Ismail-Allouche Z; Long T; McNeill A; Arafat C; England D;

Background: An increasing body of evidence highlights the utility of examining adverse childhood experiences (ACEs) utilizing person-centered analytical approaches, particularly for understanding the organization and co-occurrence of ACEs, and their contributions to risk, vulnerability, and the development of intervention efforts. Methods: In the first s ...

Article GUID: 40001056


SAVE: Self-Attention on Visual Embedding for Zero-Shot Generic Object Counting

Author(s): Zgaren A; Bouachir W; Bouguila N;

Zero-shot counting is a subcategory of Generic Visual Object Counting, which aims to count objects from an arbitrary class in a given image. While few-shot counting relies on delivering exemplars to the model to count similar class objects, zero-shot counting automates the operation for faster processing. This paper proposes a fully automated zero-shot me ...

Article GUID: 39997554


Elucidating the size distribution of p‑Phenylenediamine-Derived quinones in atmospheric particles

Author(s): Xia K; Qin M; Han M; Zhang X; Wu X; Liu M; Liu S; Wang X; Liu W; Xie Z; Yuan R; Liu Q;

Transformed from p-phenylenediamines (PPDs) antioxidant, PPD-derived quinones (PPD-Qs) have recently been recognized as emerging contaminants due to their potential negative impacts on the environment and human health. While there have been measurements of airborne PPD-Qs, the size distribution of PPD-Qs and the impact of particle size on PPD transformati ...

Article GUID: 39978217


A scoping review of harm reduction practices and possibilities among indigenous populations in Australia, Canada, and the United States

Author(s): Zolopa C; Clifasefi SL; Dobischok S; Gala N; Fraser-Purdy H; Phillips MK; Blackmore S; Wendt DC;

Background: There is a great diversity of traditions, practices, and experiences among the Indigenous Peoples of North America and Oceania. However, Indigenous Peoples across these regions are affected by the historical and ongoing violence of settler colonialism, resulting in disproportionately ...

Article GUID: 39970577


Leveraging deep learning for nonlinear shape representation in anatomically parameterized statistical shape models

Author(s): Gheflati B; Mirzaei M; Rottoo S; Rivaz H;

Purpose: Statistical shape models (SSMs) are widely used for morphological assessment of anatomical structures. However, a key limitation is the need for a clear relationship between the model's shape coefficients and clinically relevant anatomical parameters. To address this limitation, this paper proposes a novel deep learning-based anatomically par ...

Article GUID: 39953355


Identification and comprehensive characterization of moral disapproval and behavioral dysregulation-based pornography-use profiles across 42 countries

Author(s): Bothe B; Tóth-Király I; Popova N; Nagy L; Koós M; Demetrovics Z; Potenza MN; Kraus SW; Ballester-Arnal R; Batthyány D; Bergeron S; Billieux J; Briken P; Burkauskas J; Cárdenas-López G; Carvalho J; Castro-Calvo J; Chen L; Ciocca G; Corazz ...

Background and aims: The Moral Incongruence Model of Pornography Use proposes that pornography-use-related problems may be present due to problematic pornography use (PPU) and/or moral disapproval (MD) of pornography use. Despite some supporting empirical evidence, no study has tested the presenc ...

Article GUID: 39945767


Sleep neuroimaging: Review and future directions

Author(s): Pereira M; Chen X; Paltarzhytskaya A; Pache?o Y; Muller N; Bovy L; Lei X; Chen W; Ren H; Song C; Lewis LD; Dang-Vu TT; Czisch M; Picchioni D; Duyn J; Peigneux P; Tagliazucchi E; Dresler M;

Sleep research has evolved considerably since the first sleep electroencephalography recordings in the 1930s and the discovery of well-distinguishable sleep stages in the 1950s. While electrophysiological recordings have been used to describe the sleeping brain in much detail, since the 1990s neu ...

Article GUID: 39940102


Imaging flow cytometry-based cellular screening elucidates pathophysiology in individuals with Variants of Uncertain Significance

Author(s): Muffels IJJ; Waterham HR; D' Alessandro G; Zagnoli-Vieira G; Sacher M; Lefeber DJ; Van der Vinne C; Roifman CM; Gassen KLI; Rehmann H; Van Haaften-Visser DY; Nieuwenhuis ESS; Jackson SP; Fuchs SA; Wijk F; van Hasselt P;

Background: Deciphering variants of uncertain significance (VUS) represents a major diagnostic challenge, partially due to the lack of easy-to-use and versatile cellular readouts that aid the interpretation of pathogenicity and pathophysiology. To address this challenge, we propose a high-through ...

Article GUID: 39920830


International interlaboratory study to normalize liquid chromatography-based mycotoxin retention times through implementation of a retention index system

Author(s): Kelman MJ; Renaud JB; McCarron P; Hoogstra S; Chow W; Wang J; Varga E; Patriarca A; Vaya AM; Visintin L; Nguyen T; De Boevre M; De Saeger S; Karanghat V; Vuckovic D; McMullin DR; Dall' Asta C; Ayeni K; Warth B; Huang M; Tittlemier S ...

Monitoring for mycotoxins in food or feed matrices is necessary to ensure the safety and security of global food systems. Due to a lack of standardized methods and individual laboratory priorities, most institutions have developed their own methods for mycotoxin determinations. Given the diversit ...

Article GUID: 39913989


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