Author(s): Joly-Smith E; Talpur MM; Allard P; Papazotos F; Potvin-Trottier L; Hilfinger A;

Characterizing and manipulating cellular behavior requires a mechanistic understanding of the causal interactions between cellular components. We present an approach to detect causal interactions between genes without the need to perturb the physiological state of cells. This approach exploits naturally occurring cell-to-cell variability which is experime ...

Article GUID: 41401079

Author(s): Tian M; Mohammadzadeh A; Taghavifar H; Sakthivel R; Zhang C;

In this paper, a new control approach is proposed for the synchronization and stabilization of a class of chaotic systems with unknown dynamics and input nonlinearities. Type-3 fuzzy logic systems (T3-FLSs) are developed to adaptively model the dynamics of both master and slave systems in real time. The input is affected by sector-bounded hysteresis and q ...

Article GUID: 41381323

Author(s): Wolfe D; Rosenstein B; Dover G; Boily M; Fortin M;

Background: Chronic low back pain (CLBP) patients present with morphological and functional deficits to the lumbar multifidus. Electromyostimulation (EMS) can be used to improve activation and strength in atrophied skeletal muscle, but its effect on multifidus morphology and function in CLBP patients is understudied. The aims of this study were to compare ...

Article GUID: 41283552

Author(s): Fasihanifard M; Packirisamy M;

Actuating monolithic photonic components (particularly slab waveguides) requires higher force due to their inherent stiffness. However, two primary constraints must be addressed: actuator footprint and fabrication limits. Increasing the number of fingers to provide the required force is not a viable solution due to space constraints, and we must also adhe ...

Article GUID: 41156349

Author(s): MacNeil S; da Estrela C; Caldwell W; Gouin JP;

Objective: A parent's ability to self-regulate influences parenting practices. Child-related stressors may deplete parent's self-regulatory capacities. However, this effect may be moderated by the marital context within which stressful parent-child interactions are occurring. The aim of the current study was to investigate the association between ...

Article GUID: 40972822

Author(s): Abicumaran Uthamacumaran

Advancements in AI-powered systems medicine have revolutionized biomarker discovery through emergent and explainable features. By use of complex network dynamics and graph-based machine learning, we identified critical determinants of lineage-specific plasticity across the single-cell transcriptomics of pediatric high-grade glioma (pHGGs) subtypes: IDHWT ...

Article GUID: 40848317

Author(s): Hervé V; Bonenfant L; Amyot M; Balafrej R; Ali OBK; Benali H; Brouillette J;

In Alzheimer's disease, there is an imbalance in neurotransmitter release and altered neuronal activation. Here, we present a protocol approach to analyze neuronal activity by combining local field potential (LFP) recording with microdialysis within the same animal. We describe steps for measuring glutamate and GABA levels following hippocampal amyloi ...

Article GUID: 40131934

Author(s): Pakdaman S; Nouri G; Mulligan CN; Nasiri F;

Osmotic energy provides an emerging renewable alternative by leveraging the salinity gradient between two solutions. Among these technologies, pressure-retarded osmosis (PRO) has attracted attention; however, its deployment is hindered by obstacles resulting from impurities in feed and draw solutions and lack of suitable membranes. This review explores th ...

Article GUID: 40077246

Author(s): Bouliane M; Boivin M; Kretschmer T; Lafreniere B; Paquin S; Tremblay R; Côté S; Gouin JP; Andlauer TFM; Petitclerc A; Ouellet-Morin I;

Individual differences in physical aggression (PA) are largely heritable. However, it remains unclear how genetic propensity for aggression manifests early in life and relates to school-age PA. Preschool externalizing behavior problems (EXT) and adverse experiences are known predictors of school- ...

Article GUID: 39907790

Author(s): Dade MC; Bonn A; Eigenbrod F; Felipe-Lucia MR; Fisher B; Goldstein B; Holland RA; Hopping KA; Lavorel S; Lede Polain Waroux Y; MacDonald GK; Mandle L; Metzger JP; Pascual U; Rieb JT; Vallet A; Wells GJ; Ziter CD; Bennett EM; Robinson BE;

Context: There are urgent calls to transition society to more sustainable trajectories, at scales ranging from local to global. Landscape sustainability (LS), or the capacity for landscapes to provide equitable access to ecosystem services essential for human wellbeing for both current and future ...

Article GUID: 39867571

Author(s): Asadi Z; Castillo JP; Asadi M; Sinclair DS; Kersten-Oertel M;

Global disparities in neurosurgical care necessitate innovations addressing affordability and accuracy, particularly for critical procedures like ventriculostomy. This intervention, vital for managing life-threatening intracranial pressure increases, is associated with catheter misplacement rates exceeding 30% when using a freehand technique. Such misplac ...

Article GUID: 39816703