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The effect of a multimodal exercise program on paraspinal muscle morphology and clinical outcomes in chronic low back pain

Author(s): Rosenstein B; Bergevin M; Bobeuf F; Bherer L; Pageaux B; Roy M; Fortin M;

Background: Multimodal exercise programs do not specifically target lumbar paraspinal musculature, but incorporate aspects of different exercises to have an overall benefit. Objective: To investigate the effect of a multimodal exercise program on paraspinal muscle volume and composition, and patient outcomes in individuals with chronic low back pain (CLB ...

Article GUID: 42093855


Computational optical streak microscopy of megahertz acoustic microbubble dynamics

Author(s): Marquez M; Lai Y; Liu M; Memari E; Helfield B; Liang J;

Real-time dynamic imaging of microbubbles is crucial for understanding their microscale biophysical interactions and advancing ultrasound therapy. Despite progress in time-resolved optical imaging, existing techniques still face trade-offs between acquisition speed, spatial resolution, affordability, and system complexity. Here, we introduce compressed op ...

Article GUID: 42078858


Effects of aquatic therapy vs. standard care on gluteal muscle morphology and function in individuals with chronic low back pain: a randomized controlled trial

Author(s): Montpetit C; Vaillancourt N; Rosenstein B; Wesselink EO; Dover G; Weiss C; Papula LA; Melek A; Weber KA; Elliott JM; Fortin M;

Article GUID: 41943153


Strengthening and Targeted Rehabilitation for Optimal Neuromuscular Gains for chronic BACK pain (STRONG-BACK): protocol for a randomised controlled trial in participants with primary nociceptive pain drivers

Author(s): Fortin M; Rosenstein B; Bertrand C; Vaillancourt N; Wright A; Montpetit C; Macedo L; Elliott J; Cook CE; Tousignant-Laflamme Y; Ma J; Pagé MG; Dover G; Dang-Vu TT; Weber MH;

Introduction: Exercise therapy is the most recommended treatment for chronic low back pain (LBP), with evidence supporting modest effects, likely due to the heterogeneity of patient presentations. Evidence suggests that matching individuals to the most appropriate exercise type could improve outc ...

Article GUID: 41876162


Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia

Author(s): Heers M; Afnan J; Braun C; Grova C; Altenmüller DM; Steinhoff BJ; Dümpelmann M; Demerath T; Urbach H; Ethofer S; Siegel M; Schulze-Bonhage A; Lerche H; Li Hegner Y;

Objective: Focal cortical dysplasia (FCD) causes drug-resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta ( ...

Article GUID: 41804684


How vigilance states influence source imaging of physiological brain oscillations: evidence from intracranial EEG

Author(s): Wei X; Afnan J; Avigdor T; von Ellenrieder N; Delaire É; Royer J; Ho A; Minato E; Schiller K; Jaber K; Wang YL; Moye M; Bernhardt BC; Lina JM; Grova C; Frauscher B;

Cortical oscillations across sleep-wake cycles are essential for coordinating functional brain dynamics. High-density electroencephalography (HDEEG) combined with electrical source imaging (ESI) provides a noninvasive approach to map cortical dynamics; however, its ability to capture spatial ongo ...

Article GUID: 41687693


Hierarchical Storage Management in User Space for Neuroimaging Applications

Author(s): Hayot-Sasson V; Glatard T;

Neuroimaging open-data initiatives have led to increased availability of large scientific datasets. While these datasets are shifting the processing bottleneck from compute-intensive to data-intensive, current standardized analysis tools have yet to adopt strategies that mitigate the costs associated with large data transfers. A major challenge in adaptin ...

Article GUID: 41432812


Patterns of Structural Disconnection Driving Proprioceptive Deficits in Chronic Stroke

Author(s): Kaeja M; Gajiyeva L; Iturria-Medina Y; Villringer A; Sehm B; Steele C;

Background: Stroke is a leading cause of death and disability, with proprioceptive impairments affecting up to 64% of survivors. These impairments hinder sensorimotor recovery, significantly impacting poststroke quality of life. Proprioception depends on an integrated brain network but remains underexplored due to limitations in clinical assessments, hind ...

Article GUID: 41392885


Cerebral small vessel disease lesion segmentation methods: A systematic review

Author(s): Phelps J; Singh M; McCreary CR; Dallaire-Théroux C; Stein RG; Potvin-Jutras Z; Guan DX; Wu JD; Metz A; Smith EE;

Cerebral small vessel disease (CSVD) can manifest as brain lesions visible on magnetic resonance imaging, including white matter hyperintensities (WMH), cerebral microbleeds (CMB), perivascular spaces (PVS), lacunes, and recent small subcortical infarcts (RSSI). Detection and segmentation of thes ...

Article GUID: 41080650


The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond

Author(s): Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Stri ...

The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now be ...

Article GUID: 41020412


BOLD Long-Range Temporal Correlations Reflect Changes in Language and Depression Across Intensive Aphasia Therapy

Author(s): Jäger AP; Steele CJ; Dreyer FR; Osterloh MR; Sadlon A; Nikulin V; Mohr B; Pulvermüller F;

Background: Intensive language-action therapy treats language deficits and depressive symptoms in chronic poststroke aphasia, yet the underlying neural mechanisms remain underexplored. Long-range temporal correlations (LRTCs) in blood oxygenation level-dependent signals indicate persistence in brain activity patterns and may relate to learning and levels ...

Article GUID: 40927858


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