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Spatial Variations of Atmospheric Alkylated Polycyclic Aromatic Hydrocarbons across the Western Pacific to the Southern Ocean: Unexpected Increasing Deposition

Author(s): Zhu FJ; Lu XM; Jia JW; Zhang X; Xing DF; Cai MH; Kallenborn R; Li YF; Muir DCG; Zhang ZF; Zhang X;

Spatial variations of atmospheric alkylated polycyclic aromatic hydrocarbons (Alk-PAHs) are key to understanding their long-range atmospheric transport (LRAT). However, limited Alk-PAHs data have hindered their LRAT characterizations on a global scale. In this study, 49 Alk-PAHs were measured in ...

Article GUID: 40025703


Elucidating the toxicity of methyl parathion, imazapic, isoxaflutole, and chlorantraniliprole on human hepatocarcinoma cells and bioinspired membranes

Author(s): Dos Santos DM; Rubira RJG; Salzedas GP; Kobal MB; Moreira LG; Toledo KA; Aoki PHB; DeWolf C; Camacho SA;

Pesticides have boosted agricultural productivity but pose significant risks to environmental and human health. The intensification of agriculture has driven widespread pesticide use, with 66 % of global consumption allocated to sugarcane, soybean and corn. Sugarcane, a major monoculture in Brazi ...

Article GUID: 40020292


The Point of No Return? Impediments to Return to Work for Injured Migrant Agricultural Workers in Two Canadian Provinces

Author(s): Mayell S; McLaughlin J; Hennebry J; Sanchez GV; Goswami P; Hanley J;

Migrant agricultural workers employed through Canada's Temporary Foreign Worker Program face serious occupational health and safety hazards, with compounded difficulties in accessing workers' compensation (WC) if they are sick or injured by the job. Little is known, however, about their ability to return to work (RTW) upon recovery-a fundamental r ...

Article GUID: 39980401


Elucidating the size distribution of p‑Phenylenediamine-Derived quinones in atmospheric particles

Author(s): Xia K; Qin M; Han M; Zhang X; Wu X; Liu M; Liu S; Wang X; Liu W; Xie Z; Yuan R; Liu Q;

Transformed from p-phenylenediamines (PPDs) antioxidant, PPD-derived quinones (PPD-Qs) have recently been recognized as emerging contaminants due to their potential negative impacts on the environment and human health. While there have been measurements of airborne PPD-Qs, the size distribution of PPD-Qs and the impact of particle size on PPD transformati ...

Article GUID: 39978217


Leveraging deep learning for nonlinear shape representation in anatomically parameterized statistical shape models

Author(s): Gheflati B; Mirzaei M; Rottoo S; Rivaz H;

Purpose: Statistical shape models (SSMs) are widely used for morphological assessment of anatomical structures. However, a key limitation is the need for a clear relationship between the model's shape coefficients and clinically relevant anatomical parameters. To address this limitation, this paper proposes a novel deep learning-based anatomically par ...

Article GUID: 39953355


Imaging flow cytometry-based cellular screening elucidates pathophysiology in individuals with Variants of Uncertain Significance

Author(s): Muffels IJJ; Waterham HR; D' Alessandro G; Zagnoli-Vieira G; Sacher M; Lefeber DJ; Van der Vinne C; Roifman CM; Gassen KLI; Rehmann H; Van Haaften-Visser DY; Nieuwenhuis ESS; Jackson SP; Fuchs SA; Wijk F; van Hasselt P;

Background: Deciphering variants of uncertain significance (VUS) represents a major diagnostic challenge, partially due to the lack of easy-to-use and versatile cellular readouts that aid the interpretation of pathogenicity and pathophysiology. To address this challenge, we propose a high-through ...

Article GUID: 39920830


Prioritizing Chemical Features in Non-targeted Analysis through Spatial Trend Analysis: Application to the Identification of Organic Chemicals Subject to Mountain Cold-Trapping

Author(s): Zhang X; Zhan F; Hao C; Lei YD; Wania F;

One of the challenges arising during non-targeted analysis (NTA) is that the number of detected chemical features is generally too large for detailed processing and interpretation. Here, we illustrate how the analysis of spatial trends in peak intensities can be an effective tool to prioritize chemical features in NTA. Specifically, features detected by g ...

Article GUID: 39912640


The PolyVent educational platform: An open mechanical ventilation platform for research and education

Author(s): Read RL; Bechard N; Suturin V; Zuiderwijk A; Mellenthin M;

The PolyVent is an open source mechanical ventilator meant for research and education. It prioritizes openness, modularity, repairability, and modifiability. An ESP32 microcontroller controls a proportional valve which precisely modulates pressure and flow from a mixing chamber into the airway. This chamber is fed with pressurized oxygen and medical air. ...

Article GUID: 39895909


Human recreational activity does not influence open cup avian nest survival in urban green spaces

Author(s): Cull CA; Guest MJ; Frei B; Ziter CD;

The breeding period of birds is a critical and sensitive portion of the annual cycle. Understanding how human use of urban green spaces affects nest survival can improve our understanding of conserving breeding bird populations in cities and support science-based management of urban green spaces that benefit both people and nature. We conducted a nest sur ...

Article GUID: 39897430


Exposure to hate in online and traditional media: A systematic review and meta-analysis of the impact of this exposure on individuals and communities

Author(s): Madriaza P; Hassan G; Brouillette-Alarie S; Mounchingam AN; Durocher-Corfa L; Borokhovski E; Pickup D; Paillé S;

The problem: People use social media platforms to chat, search, and share information, express their opinions, and connect with others. But these platforms also facilitate the posting of divisive, harmful, and hateful messages, targeting groups and individuals, based on their race, religion, gend ...

Article GUID: 39822240


Psychosocial Function in Mild Cognitive Impairment: Social Participation is Associated With Cognitive Performance in Multiple Domains

Author(s): Rehan S; Phillips NA;

Psychosocial function is associated with cognitive performance cross-sectionally and cognitive decline over time. Using data from the COMPASS-ND study, we examined associations between psychosocial and cognitive function in 126 individuals with mild cognitive impairment, an at-risk group for Alzheimer's disease (AD). Psychosocial function was measured ...

Article GUID: 39773214


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