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A person-centered examination of adverse childhood experiences and associated distal health, mental health, and behavioral outcomes in the United Arab Emirates

Author(s): Murphy A; Elbarazi I; Horen N; Ismail-Allouche Z; Long T; McNeill A; Arafat C; England D;

Background: An increasing body of evidence highlights the utility of examining adverse childhood experiences (ACEs) utilizing person-centered analytical approaches, particularly for understanding the organization and co-occurrence of ACEs, and their contributions to risk, vulnerability, and the development of intervention efforts. Methods: In the first s ...

Article GUID: 40001056


In Shift and In Variance: Assessing the Robustness of HAR Deep Learning Models Against Variability

Author(s): Khaked AA; Oishi N; Roggen D; Lago P;

Deep learning (DL)-based Human Activity Recognition (HAR) using wearable inertial measurement unit (IMU) sensors can revolutionize continuous health monitoring and early disease prediction. However, most DL HAR models are untested in their robustness to real-world variability, as they are trained on limited lab-controlled data. In this study, we isolated ...

Article GUID: 39860799


The long shadow of accumulating adverse childhood experiences on mental health in the United Arab Emirates: implications for policy and practice

Author(s): Murphy A; England D; Elbarazi I; Horen N; Long T; Ismail-Allouche Z; Arafat C;

Introduction: This study investigates the cumulative effects of adverse childhood experiences (ACEs) on adult depression, anxiety, and stress in Abu Dhabi, controlling for demographic factors, lifestyle, and known health and mental health diagnoses. Methods: Utilizing a cross-sectional design and self-report measures, the research aims to fill a critical ...

Article GUID: 39100953


Evaluation of human vulnerability and toxic effects of chronic and acute occupational exposure to ammonia: A case study in an ice factory

Author(s): Soltanzadeh A; Mahdinia M; Nikbakht N; Hosseinzadeh K; Sadeghi-Yarandi M;

Background: The hazardous material release has frequently occurred worldwide. As a respiratory stimulant and a toxic substance, ammonia has numerous adverse effects on human health. Objective: The purpose of this study was to evaluate the human vulnerability and toxic effects of both chronic and acute respiratory exposure to ammonia. Methods: This study ...

Article GUID: 38143407


Trabecular Bone Score Preceding and during a 2-Year Follow-Up after Sleeve Gastrectomy: Pitfalls and New Insights

Author(s): Joshua Stokar

Bariatric surgery (BS) can have negative effects on bone health. Bone microarchitecture quality evaluation using the trabecular bone score (TBS) has not been described in patients after sleeve gastrectomy (SG). To test the hypothesis that the TBS is clinically useful for this population, we evaluated changes in bone mineral density (BMD) and the TBS in a ...

Article GUID: 37571418


Oligonucleotides Containing C5-Propynyl Modified Arabinonucleic Acids: Synthesis, Biophysical and Antisense Properties

Author(s): Pontarelli A; Wilds CJ;

The introduction of chemical modifications on the nucleic acid scaffold has allowed for the progress of antisense oligonucleotides (ASOs) in the clinic for the treatment of a variety of disorders. In contribution to the repertoire of gene-silencing nucleic acid modifications, herein we report the synthesis and incorporation of C5-propynyl arabinouridine ( ...

Article GUID: 36857293


Outdoor heat stress assessment using an integrated multi-scale numerical weather prediction system: A case study of a heatwave in Montreal

Author(s): Katal A; Leroyer S; Zou J; Nikiema O; Albettar M; Belair S; Wang L;

More frequent and severe extreme weather events such as heatwaves are among the most serious challenges to society in coping with the changing climate. To evaluate the impacts of the heatwave on large-scale urban areas, a multi-scale weather forecasting system is designed by integrating different resolutions of the Canadian urbanized version of the Global ...

Article GUID: 36587678


We're building it up to burn it down: fire occurrence and fire-related climatic patterns in Brazilian biomes

Author(s): Diele Viegas LM; Sales L; Hipólito J; Amorim C; Johnson de Pereira E; Ferreira P; Folta C; Ferrante L; Fearnside P; Mendes Malhado AC; Frederico Duarte Rocha C; M Vale M;

Background: Terrestrial biomes in South America are likely to experience a persistent increase in environmental temperature, possibly combined with moisture reduction due to climate change. In addition, natural fire ignition sources, such as lightning, can become more frequent un ...

Article GUID: 36312759


Arabinonucleic Acids Containing C5-Propynyl Modifications Form Stable Hybrid Duplexes with RNA that are Efficiently Degraded by E. coli RNase H

Author(s): Pontarelli A; Wilds CJ;

The promise of the antisense approach to treat a variety of diseases with oligonucleotides and solutions to challenges that have been encountered in their development is attributable to chemical modification of the nucleic acid scaffold. Herein, we describe preliminary data regarding the synthesis of a novel C5-propynyl-ß-D-arabinouridine (araUP) phosphor ...

Article GUID: 35452799


An analysis of security vulnerabilities in container images for scientific data analysis

Author(s): Kaur B; Dugré M; Hanna A; Glatard T;

Background: Software containers greatly facilitate the deployment and reproducibility of scientific data analyses in various platforms. However, container images often contain outdated or unnecessary software packages, which increases the number of security vulnerabilities in the images, widens the attack surface in the container host, and creates substan ...

Article GUID: 34080631


On the Impact of Biceps Muscle Fatigue in Human Activity Recognition.

Author(s): Elshafei M, Costa DE, Shihab E

Nowadays, Human Activity Recognition (HAR) systems, which use wearables and smart systems, are a part of our daily life. Despite the abundance of literature in the area, little is known about the impact of muscle fatigue on these systems' performance. In this work, we use the biceps concentration curls exercise as an example of a HAR activity to obser ...

Article GUID: 33557239


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