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Multilingualism and cognitive reserve in older adults with, or at risk for, Alzheimer s disease: Evidence from resting-state functional connectivity

Author(s): Coulter K; Dash T; Best T; Grant N; Ansaldo AI; Phillips NA;

Speaking more than one language is hypothesized to lead to greater brain resilience in aging and Alzheimer's disease, resulting in a delay in the symptom onset of Alzheimer's disease. While previous research has used structural neuroimaging measures to explore the neural underpinnings of this protective effect, few studies have used functional b ...

Article GUID: 42208339


Keeping an Eye on Looking Measures: Towards More Robust Developmental Methods

Author(s): Sander-Montant A; Fibla L; Killam H; Byers-Heinlein K;

A persistent challenge in experimental developmental psychology is determining which of many possible outcome measures best captures underlying behaviors and processes. In the looking-while-listening paradigm for studying early word comprehension, researchers have developed more than 12 distinct outcome measures, but have limited empirical basis for cho ...

Article GUID: 42206598


Investigating substrate specificity in arogenate versus prephenate dehydratases

Author(s): Clayton EJ; Smith-Uffen M; Tribble TW; Duennwald ML; Kohalmi SE;

Background: Phenylalanine is an essential aromatic amino acid that can only be synthesized de novo by microorganisms and plants. In microorganisms, phenylalanine is synthesized through the prephenate pathway, requiring the activity of a prephenate dehydratase (PDT). In plants, phenylalanine is synthesized instead mostly through the arogenate pathway, re ...

Article GUID: 42204708


Hand to Mouth: Shifting the Bare-Minimum Accessibility Paradigm in XR Through Crip-Hacking and Crip-Aesthetics

Author(s): Jain P; Bayerlein C;

eXtended Reality (XR) technologies often embed ableist design assumptions, privileging hand-based interaction and vision-centric interfaces that presume a normative able-bodied user. As a result, many disabled people-including those with limited mobility or blindness-are excluded from the outset, with accessibility added only as an afterthought. We crit ...

Article GUID: 42182821


Does Intranasal Oxytocin Reduce Symptoms of Mental Disorders? A Meta-Analysis of Clinical Trials

Author(s): Bonnieux J; Gumuchian ST; Harboun A; Trespalacios F; Bélisle KA; Haddad A; Quintus-Bosz O; McLellan A; Chester-Trudel L; Garred D; Resendes T; Hazel L; Wong SF; Ellenbogen MA;

Intranasal administration of oxytocin has been shown to enhance social cognition and reduce stress reactivity in healthy individuals, suggesting therapeutic potential for mental disorders. However, clinical trials have produced mixed results. Following a systematic search, data were extracted f ...

Article GUID: 42134427


Enhanced Lower Limb Strength and Dynamic Balance Among Older Canadian Women Following 12-Weeks of Online Ballet-Modern Dance Classes Combined with Blood Flow Restriction

Author(s): Chen EH; Saminathar AJ; Roberts M; Bergdahl A;

Introduction: Falls are a leading cause of hospitalization among older women. While dance classes have gained popularity to reduce the risk of falls, in-person classes may be inaccessible. Online classes provide feasible solutions, but are limited by the lower intensity required by the virtual environment. Blood flow restriction (BFR) provides a safe wa ...

Article GUID: 42132210


Artificial intelligence for marine oil spill management: Recent advances and future directions

Author(s): Wang Z; Huang Y; Zhang G; Wang Z; Chen Z; Mulligan CN; Li SS; Elektorowicz M; Li B; Lee K; An C;

Marine oil spills are one of the most severe anthropogenic threats to oceanic ecosystems, coastal communities, and global economic stability. While traditional monitoring and response approaches have played a foundational role in oil spill management, their effectiveness is often constrained by ...

Article GUID: 42119407


Sex-specific anxiety and depression multi-trajectories and associated risk factors in the Canadian Partnership for Tomorrow s Health longitudinal study

Author(s): Kapasa RL; Grenon C; Berbiche D; Gouin JP; Vena JE; Vasiliadis HM;

Aims: This study identified sex-specific multi-trajectories of anxiety and depression symptoms among Canadians before and during the COVID-19 pandemic, and associated factors according to a public mental health framework for the surveillance of mental health. Methods: Data from 15,021 participants in the Canadian Partnership for Tomorrow's Health c ...

Article GUID: 42107659


A digital cognitive behavioural therapy programme for insomnia and anxiety in older adults: feasibility and preliminary efficacy

Author(s): Reyt M; Adoutoro J; Borgetto F; Desrosiers C; Barbaux L; Gong K; Savard J; Grenier S; Dang Vu TT;

Insomnia and anxiety are highly prevalent and often comorbid in older adults. Although cognitive behavioural therapy is the first-line treatment for insomnia, few interventions simultaneously address both conditions. Furthermore, access remains limited by provider availability and high costs. T ...

Article GUID: 42096653


Computational optical streak microscopy of megahertz acoustic microbubble dynamics

Author(s): Marquez M; Lai Y; Liu M; Memari E; Helfield B; Liang J;

Real-time dynamic imaging of microbubbles is crucial for understanding their microscale biophysical interactions and advancing ultrasound therapy. Despite progress in time-resolved optical imaging, existing techniques still face trade-offs between acquisition speed, spatial resolution, affordability, and system complexity. Here, we introduce compressed ...

Article GUID: 42078858


Advanced Separators for Liquid and Quasi-Solid Lithium Rechargeable Batteries: Design and Development

Author(s): Vishweswariah K; Ningappa NG; Kumar M R A; Dawkins JIG; Selva TMG; Zaghib K;

Separators have evolved from passive polymeric barriers into multifunctional components that critically govern the performance, safety, and lifetime of liquid and quasi-solid lithium rechargeable batteries. This Review provides a comprehensive analysis of separator materials and architectures spanning commercial polyolefins and their ceramic coatings, h ...

Article GUID: 42015518


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