Author(s): Jobin B; Phillips NA; Frasnelli J; Boller B;

BackgroundOlfactory identification decline is a known early marker of Alzheimer's disease and is already present at the mild cognitive impairment (MCI) stage. While being linked with episodic memory, its predictive value for cognitive performance and distinguishing between clinical stages remains unclear.ObjectiveThis study examined (1) the predictive ...

Article GUID: 40944318

Author(s): Brown A; Gervais NJ; Gravelsins L; O' Byrne J; Calvo N; Ramana S; Shao Z; Bernardini M; Jacobson M; Rajah MN; Einstein G;

Bilateral salpingo-oophorectomy (BSO; removal of ovaries and fallopian tubes) prior to age 48 is associated with elevated risk for both Alzheimer's disease (AD) and sleep disorders such as insomnia and sleep apnea. In early midlife, individuals with BSO show reduced hippocampal volume, functi ...

Article GUID: 39178647

Author(s): Papadatos Z; Phillips NA;

We examined cognitive domains and brain regions associated with olfactory performance in cognitively unimpaired older adults (CU-OAs) and individuals with or at risk for Alzheimer's Disease (AD). We compared CU-OAs (N = 55), individuals with subjective cognitive decline (SCD, N = 55), mild cognitive impairment (MCI, N = 101), and AD (N = 45) on measur ...

Article GUID: 37146503

Author(s): Lockrow AW; Setton R; Spreng KAP; Sheldon S; Turner GR; Spreng RN;

Autobiographical memory (AM) involves a rich phenomenological re-experiencing of a spatio-temporal event from the past, which is challenging to objectively quantify. The Autobiographical Interview (AI; Levine et al. Psychology and Aging, 17(4), 677-689, 2002) is a manualized performance-based assessment designed to quantify episodic (internal) and semanti ...

Article GUID: 36944860