Author(s): Intzandt B; Potvin-Jutras Z; Gauthier CJ;

Circulating sex hormone levels decrease in aging, influencing cerebrovascular health. Estradiol has been shown to support female vascular and brain health, though its effects across the menopausal transition remain unknown. Similarly, the influence of testosterone and other hormones in females is not clear. In males, testosterone is associated with posi ...

Article GUID: 42361914

Author(s): Diep J; Chen E; Lui JHL;

Background: Youths with disruptive behaviours (DB) and callous-unemotional (CU) traits experience significant impairments and impose substantial costs on families and society. Treatment outcome studies of current DB treatments highlight the need for tailored treatments. Identifying priority treatment targets that integrate empirical evidence with stakeh ...

Article GUID: 42351288

Author(s): Bherer L; Besnier F; Gagnon C; Vrinceanu T; Vincent T; Mohammadi H; Gauthier C; Duquesne C; Blanchette CA; Bérubé B; Said SN; Iglesies-Grau J; L' Allier P; Boulet J; Nigam A; Dionne V; Benhalima H; Dubé MP; Duchesne S; Belleville ...

Cognitive impairment can affect up to 50% of patients with chronic heart failure (CHF) and is associated with reduced treatment adherence, high mortality rates, and poor quality of life. Nonpharmacologic strategies, including cognitive intervention and physical exercise training, may help enhan ...

Article GUID: 42327429

Author(s): Rasoulivalajoozi M; Farhoudi M;

Purpose: Wheelchairs should support not only safe and intuitive navigation but also positive social presence without reinforcing disability-related stereotypes. This study introduces a user-centred external communication framework (ECF) to guide the design of wheelchair external human-machine interfaces and their perceptual dimensions.Materials and meth ...

Article GUID: 42300838

Author(s): Nikolic M; Caswell CB; Prada NP; Iqbal M; Cox SML; Jaworska N; Castellanos-Ryan N; Vitaro F; Brendgen M; Parent S; Boivin M; Côté S; Tremblay RE; Séguin JR; Leyton M;

Background: We recently reported evidence that a biopsychosocial model predicts lifetime histories of commonly comorbid early-onset psychiatric disorders. This transdiagnostic model was produced when incorporating either positron emission tomography-measured midbrain dopamine autoreceptors or f ...

Article GUID: 42293407

Author(s): Zheng S; Qian B; Chen X; Kishk AA;

Dense direct-current (DC) bias routing and numerous radio-frequency (RF) choke inductors pose major challenges to the practical implementation of phase-shifter-free beam steering using PIN-controlled phase switching. To address this issue, a compact vertical DC biasing network is proposed, in which most DC bias lines are routed beneath the ground plane. ...

Article GUID: 42281100

Author(s): Wu N; Joyal-Desmarais K; Linkins LA; Flórez ID; Bacon SL;

Background: The COVID-19 pandemic demanded evidence synthesis approaches that could keep pace with rapidly evolving science and urgent policy needs. Rapid reviews and living evidence syntheses (LES) emerged as critical methodological responses, yet limited guidance exists for teams undertaking such work, particularly regarding the operational challenges ...

Article GUID: 42282099

Author(s): Yang W; Wang X; Li H; Liu W; Chen Z; Ren B; Guo T; Guo J;

Co-pollution of nitrate and tetracycline (TC) poses a critical barrier to efficient biological treatment due to impaired electron transfer, diminished microbial metabolic activity, and disrupted community structure. To address this challenge, this study synthesized an iron-nitrogen-doped carbon material (Fe-NC) featuring electron-withdrawing pyridinic n ...

Article GUID: 42259450

Author(s): MacPherson A; Caizergues AE; Savary P; Xu K; Messer PW; Akbar MN; Fortin MJ; Holt RD; Hoi AG; Mideo N; Ness R; Peres-Neto PR; Santangelo JS; Johnson MTJ;

Urbanization drives rapid and extreme environmental change, profoundly shaping the ecology and evolution of populations. In this Perspective, we call for the integration and development of evolutionary theory and empirical research through collaboration between theoretical and experimental biol ...

Article GUID: 42253486

Author(s): Chukwuejim S; Fatoki TH; Aluko RE;

Arginase is a binuclear manganese metalloenzyme that modulates L-arginine availability and downstream metabolic pathways. It was hypothesized that C-terminal arginine-containing peptides generated through simulated gastrointestinal digestion of white lupin (Lupinus albus) proteins would exhibit arginase inhibitory activity. To test this hypothesis, inte ...

Article GUID: 42232067

Author(s): Freeman-Cole CE; Jaeger JAG;

While landscape connectivity is an important focus of Canada's conservation goals, Canadian national parks are vulnerable to habitat loss, the breaking-up of habitat patches, and a reduction in their connectivity to surrounding ecosystems. This study measured landscape fragmentation in 43 Canadian national parks and control areas throughout their hi ...

Article GUID: 42228295