Author(s): Greco BM; Zapata G; Dandage R; Papkov M; Pereira V; Lefebvre F; Bourque G; Parts L; Kuzmin E;

Whole-genome duplication (WGD) events are common across various organisms; however, the retention and evolution of WGD paralogs is not fully understood. Quantitative measure of protein redistribution in response to the deletion of their WGD paralog provides insight into sources of gene retention. ...

Article GUID: 40580499

Author(s): Dandage R; Papkov M; Greco BM; Pereira V; Fishman D; Friesen H; Wang K; Styles EB; Kraus O; Grys B; Zapata G; Lefebvre F; Bourque G; Boone C; Andrews BJ; Parts L; Kuzmin E;

Gene duplication is common across the Tree of Life and contributes to genomic robustness. In this study, we examined changes in the subcellular localization and abundance of proteins in response to the deletion of their paralogs originating from the whole-genome duplication event, which is a larg ...

Article GUID: 40585364

Author(s): Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Da ...

Study objectives: Insomnia in older adults is associated with widespread benzodiazepine (BZD) and benzodiazepine receptor agonist (BZRA) use, despite evidence that chronic use disrupts sleep regulation and cognition. Little is known about BZD/BZRA effects on NREM slow oscillations (SO), spindles ...

Article GUID: 40570297

Author(s): Grant N; Phillips N;

Mild cognitive impairment (MCI) and hearing loss (HL) have been separately associated with increased dementia risk. These highly co-occurring dementia risk factors are associated with aberrant functional brain connectivity. In individuals with HL aberrant functional connectivity has been associated with cognitive impairment. In individuals with MCI, aberr ...

Article GUID: 40567819

Author(s): Cai Z; Pellegrino G; Spilkin A; Delaire E; Uji M; Abdallah C; Lina JM; Fecteau S; Grova C;

Background: The relationship between task-related hemodynamic activity and brain excitability is poorly understood in humans as it is technically challenging to combine simultaneously non-invasive brain stimulation and neuroimaging modalities. Cortical excitability corresponds to the readiness to ...

Article GUID: 40567300

Author(s): Iravani R; Biagi M; Laforest S; Lee K; Isaacman L; Chen Z; An C;

There is growing concern regarding the environmental protection of shorelines in Canadian Indigenous communities, as these regions face increasing threats from pollution and environmental degradation. This review examines various types of pollution affecting coastal Indigenous communities, such as oil spills, plastic waste, industrial runoff, and other co ...

Article GUID: 40554913

Author(s): Maïano C; Morin AJS; Hue O; Tracey D; Craven RG;

Article GUID: 40553251

Author(s): Foroughi S; Karamzadeh V; Habibi M; Packirisamy M;

Direct sound printing (DSP) is a recent development in additive manufacturing processes using sound waves, in which cavitation bubbles created by a focused ultrasound field polymerize the liquid resin via the sonochemistry route. This article presents the first attempt to create functional parts, such as cantilevers and millifluidic systems in polydimethy ...

Article GUID: 40538575

Author(s): Silva MCJD; Pinto AMV; Balthar MA; Correa ABA; Bhattacharyya D; Simas ABC; Kuca K; Forgione P; França TCC; Cavalcante SFA; Kitagawa DAS;

Given the recent deployment of nerve agents as a method of warfare and in targeted assassinations, the development of robust, broad-spectrum medical countermeasures is essential. Our research group has synthesized isatin-pyridine oxime hybrids that have previously demonstrated the ability to resc ...

Article GUID: 40516590

Author(s): Deravian B; Mulligan CN;

Biosurfactants have emerged as promising agents for environmental remediation due to their ability to complex, chelate, and remove heavy metals from contaminated environments. This review evaluates their potential for recovering critical minerals from waste materials to support renewable energy production, emphasizing the role of biosurfactant-metal inter ...

Article GUID: 40509347

Author(s): Arshad F; Ferrari MA; Murch WS; Cherkasova MV; Limbrick-Oldfield EH; Winstanley CA; Clark L;

Modern slot machines can create immersive experiences for gamblers. Design features, including audiovisual cues, may influence these experiences, potentially interacting with personal risk factors for disordered gambling. According to the incentive salience hypothesis of addiction, reward-paired ...

Article GUID: 40504292