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Characterizing forearm skeletal muscle composition and function in breast cancer-related lymphedema using B-mode ultrasonography

Author(s): Whyte J; Towers A; Boily M; Rosenthall L; Rivaz H; Kilgour RD;

Background: Skeletal muscle thickness, echo intensity, and quality are important morphological properties; however, little is known how these variables compare between the affected and unaffected forearms in breast cancer-related lymphedema (BCRL). Methods: Using B-mode ultrasound, we recorded the raw radiofrequency data of the affected and unaffected fo ...

Article GUID: 41674486


Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset

Author(s): Mansur A; Joseph R; Kim ES; Jean-Beltran PM; Udeshi ND; Pearce C; Jiang H; Iwase R; Milev MP; Almousa HA; McNamara E; Widrick J; Perez C; Ravenscroft G; Sacher M; Cole PA; Carr SA; Gupta VA;

Ubiquitin-proteasome system (UPS) dysfunction is associated with the pathology of a wide range of human diseases, including myopathies and muscular atrophy. However, the mechanistic understanding of specific components of the regulation of protein turnover during development and disease progressi ...

Article GUID: 37432316


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