Keyword search (3,448 papers available)


Prospective Impact of Psychiatric Disorders on Employment Status and Health Care Use in Patients Investigated for Occupational Asthma.

Author(s): Lavoie KL, Favreau H, Paine NJ, Lemière C, Joseph M, Gagnon-Chauvin A, Cartier A, Bacon SL

J Occup Environ Med. 2016 12;58(12):1196-1201 Authors: Lavoie KL, Favreau H, Paine NJ, Lemière C, Joseph M, Gagnon-Chauvin A, Cartier A, Bacon SL

Article GUID: 27930478
Association Between Depression, Lung Function and Inflammatory Markers in Patients with Asthma and Occupational Asthma.

Author(s): Paine NJ, Joseph MF, Bacon SL, Julien CA, Cartier A, Ditto B, Favreau H, Lavoie KL

J Occup Environ Med. 2019 Mar 01;: Authors: Paine NJ, Joseph MF, Bacon SL, Julien CA, Cartier A, Ditto B, Favreau H, Lavoie KL

Article GUID: 30855523
Title:Association Between Depression, Lung Function and Inflammatory Markers in Patients with Asthma and Occupational Asthma.
Authors:Paine NJ,  Joseph MF,  Bacon SL,  Julien CA,  Cartier A,  Ditto B,  Favreau H,  Lavoie KL
Link:https://www.ncbi.nlm.nih.gov/pubmed/30855523?dopt=Abstract
Category:J Occup Environ Med
PMID:30855523
Dept Affiliation: HKAP
1 School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK (Dr Paine), Montreal Behavioural Medicine Centre, Research Centre, Centre intégrée universitaire de services de santé et de services sociaux du Nord-de-l'Île-de-Montréal, Hôpital du Sacré-Cœur de Montréal, Montréal, Quebec, Canada (Dr Paine, Dr Joseph, Dr Bacon, Julien, Drs Cartier, Favreau, Lavoie), Department of Exercise Science, Concordia University, Montreal, Quebec, Canada (Dr Bacon), Department of Psychology, University of Québec at Montréal (UQAM), Montréal, Quebec, Canada (Julien, Dr Lavoie), Department of Medicine, Université de Montréal, Montréal, Quebec, Canada (Dr Cartier), and Department of Psychology, McGill University, Montréal, Quebec, Canada (Dr Ditto).

Description:

Association Between Depression, Lung Function and Inflammatory Markers in Patients with Asthma and Occupational Asthma.

J Occup Environ Med. 2019 Mar 01;:

Authors: Paine NJ, Joseph MF, Bacon SL, Julien CA, Cartier A, Ditto B, Favreau H, Lavoie KL

Abstract

OBJECTIVE: Depression is associated with autonomic and immune dysregulation, yet this remains poorly explored in asthma. We assessed associations between depressive disorder, lung function, and inflammatory markers in patients under investigation for occupational asthma (OA).

METHODS: One hundred twelve patients under investigation for OA (60% men) underwent a psychiatric interview to assess depressive disorder, and spirometry, a methacholine test, sputum induction, and specific inhalation challenge (SIC) to assess OA. Blood and sputum inflammatory markers were assessed.

RESULTS: There was a statistically significant association between depressive disorder (P?=?0.0195) and forced expiratory volume in 1?second (FEV1) responses, with the drop in FEV1 post-SIC smaller in patients with OA and depression, versus OA with no depression (P?<?0.001).

CONCLUSION: The presence of depressive disorder may influence FEV1 in patients with OA, which may be via autonomic pathways. However, further studies are warranted in order to determine the mechanisms that underlie these effects.

PMID: 30855523 [PubMed - as supplied by publisher]