Author(s): Maarouf-Mesli N; Fonseca JC; Harvey SM; Chauhan PS; Mulumba M; Ahsanullah None; Selka A; Meneksedag Erol D; Chemtob S; Ong H; Polyak F; Lubell WD;

Modern macrocyclic peptides feature unnatural elements that are used to improve the activity and pharmacokinetic properties. Chemistry beyond peptide synthesis must, however, be employed to introduce such elements. Notably, application of the copper-catalyzed aldehyde-alkyne-amine A3-reaction in ...

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