Author(s): Ruiz-Blais S; Bernardi NF; Intartaglia B; Snow S; Lehmann A;

Singing and vocalization practices are reportedly associated with increased relaxation, better emotional regulation, and enhanced social closeness. Here, we investigate the neural underpinnings of such effects and ask whether they are related to processes linked to the vocalization aspect or are a result of modified breathing patterns. Toning is a form of ...

Article GUID: 42054483

Author(s): Maarouf-Mesli N; Fonseca JC; Harvey SM; Chauhan PS; Mulumba M; Ahsanullah None; Selka A; Meneksedag Erol D; Chemtob S; Ong H; Polyak F; Lubell WD;

Modern macrocyclic peptides feature unnatural elements that are used to improve the activity and pharmacokinetic properties. Chemistry beyond peptide synthesis must, however, be employed to introduce such elements. Notably, application of the copper-catalyzed aldehyde-alkyne-amine A3-reaction in ...

Article GUID: 42049622

Author(s): Harsanyi H; Slot N; Parkinson R; Morielli AR; Jeyapalan A; Holmes E; Flynn S; Campbell T; Quan H; Zeng Y; Yang J; Singh S; Vena J; Biddle S; Friedenreich CM; Yang L;

Article GUID: 42015269

Author(s): Sajedi S; An C;

The widespread use of single-use plastic (SUP) water bottles has raised growing concerns about chronic human exposure to nanoplastics (NPs). This study presents a quantitative assessment of NP accumulation in human tissues resulting from the long-term consumption of SUP water bottles. Using survey-derived consumption data and the Human Exposure and Absorp ...

Article GUID: 42007012

Author(s): Ha GS; Basak B; Ahn HJ; Baek G; Hwang JH; Roh HS; Chung WJ; Jeon BH;

The commercial viability of microalgal biorefineries is currently constrained by high energy demands during pretreatment and incomplete biomass valorization arising from cell wall recalcitrance. To overcome these challenges, this study developed a high-efficiency simultaneous saccharification and fermentation (SSF) strategy using an immobilized tri-enzyme ...

Article GUID: 41997248

Author(s): Côté M; Ramos Salas X; Carrière K; Alberga AS;

Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs), are approved for the treatment of type 2 diabetes, obesity, and related conditions, and have demonstrated significant benefits for individuals with these conditions. However, in recent years, public interest and demand for GLP-1RAs-often driven by media, social media ...

Article GUID: 41986775

Author(s): Gamache I; Fagbemi K; Harnois-Leblanc S; Greenwood CMT; Henderson M; Van Hulst A; Timpson NJ; Manousaki D;

Aims/hypothesis: Dysglycaemia in youth results from complex interactions between genetic and environmental factors, yet their individual and combined contributions remain unclear. We aimed to: (1) evaluate the predictive performance of polygenic risk scores (PRSs) for glycaemic traits from childh ...

Article GUID: 41986816

Author(s): Kafian Safari M; Mirzae M; Gheflati B; Sharifzade M; Zuhars J; Rottoo S; Rivaz H;

Purpose: Computer- and robotic-assisted technologies improve total knee arthroplasty (TKA) through intraoperative bone registration. However, limited bone exposure restricts point collection to the distal femur, omitting key geometric features and reducing registration accuracy and the surgical outcomes. Methods: We introduce a deep learning-based method ...

Article GUID: 41984365

Author(s): Brouillette-Alarie S; Hassan G; Varela W; Danis E; Ousman S; Madriaza P; Pauls IL; Kilinc D; Pickup D; Pelzer R; Borokhovski E;

Assessment of the risk of engaging in a violent radicalization/extremism trajectory has evolved quickly in the last 10 years. Guided by what has been achieved in psychology and criminology, scholars from the field of preventing violent extremism (PVE) have tried to import key lessons from violenc ...

Article GUID: 41978672

Author(s): Griffith J; Lord JM; Catchen MD; Arce-Plata MI; Blanchet FG; Chandramohan M; Diaz-Corzo MC; Gravel D; Gutiérrez C; Helfenstein IS; Hoban S; Kass JM; Laikre L; Larocque G; Leigh DM; Leung B; Mastretta-Yanes A; Millette KL; Berbeo MAM; Ngu ...

The Convention on Biological Diversity's Kunming-Montreal Global Biodiversity Framework (GBF) sets ambitious goals to protect and restore biodiversity. It includes a monitoring framework that mandates countries to track progress toward these goals using indicators that summarize biodiversity ...

Article GUID: 41971256

Author(s): Alberga AS; Forouhar V; Lurye V; Adamo KB; Avery S; Ball GDC; Farnesi BC; Gaudet L; Nagpal TS; Piccinini-Vallis H; Ramos Salas X; Rhodes RE; Vallis M; Cook J; Graham TM; Stanworth-Belleville K; Cohen TR;

Background: Conversations regarding health behaviours, mental health, and socioeconomic contexts are recommended during prenatal visits to optimize maternal and fetal health outcomes. This study was designed to develop and evaluate the acceptability of a clinical dialogue tool called Conversation ...

Article GUID: 41964085