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Management of brain-heart multimorbidity: a clinical practice guideline

Author(s): Edwards JD; Li Z; McFarlane P; Rabi DM; Gilbert J; Bajaj HS; MacIntosh BJ; Bittman J; Feldman RD; Dresser G; Terenzi K; Swartz R; Gabor J; Pearson GJ; Selby P; Wharton S; Warburton DER; Pakhalé S; Styra R; Baker B; Tu K; Hawkins M; Stone ...

Background: Although brain and heart conditions share overlapping risk factors and commonly co-occur, current cardiac and neurologic clinical guidelines are typically produced within specialty silos. The objective of this guideline from a Canadian Cardiovascular Harmonized National Guideline Ende ...

Article GUID: 41912243


Improved electrical performance of PDMS and PEDOT: PSS composites with MWCNT and AgNP particles

Author(s): Shafagh SH; Deen I; Packirisamy M;

The fabrication of conductive polymer composites (CPCs) using polydimethylsiloxane (PDMS) and poly(3,4-ethylene dioxythiophene): poly(4-styrene-sulfonate) (PEDOT: PSS) as a matrix with multi-walled carbon nanotubes (MWCNTs) and silver nanoparticles (AgNPs) as fillers was investigated to determine their potential for use in applications such as electromagn ...

Article GUID: 41424586


Effects of delayed post-polymerization on physical, chemical, and biological properties of a 3D printing interim resin

Author(s): Choi Y; Comeau P; Lim BS; Manso AP; Chung SH;

Objectives: This study evaluated the effects of delayed post-polymerization on color, degree of conversion (DC), flexural strength (FS), and cellular response of a 3D-printed dental interim resin. Methods: Specimens were divided into six groups based on delays of 0 h, 2 h, 4 h, 6 h, 8 h, and 10 h before post-polymerization. Color was characterized using ...

Article GUID: 41152035


All-Inclusive Sensing Tablet with Integrated Passive Mixer for Ultraviscous Solutions

Author(s): Safiabadi Tali SH; Al-Kassawneh M; Mansouri M; Sadiq Z; Jahanshahi-Anbuhi S;

Developing low-cost and easy-to-use point-of-care devices is necessary for timely disease diagnosis and health monitoring. Here, we introduce all-inclusive, tablet-based chemo/biosensors with rapid automixing features, capable of mixing in highly viscous solutions with viscosities up to 1700 mPa·s. These tablets are created using a simple powder compressi ...

Article GUID: 40327804


PEDOT:PSS-MWCNT Nanocomposite Wire for Routing in Energy Harvesting Devices

Author(s): Shafagh SH; Deen I; Mamsapuram Panneerselvam D; Packirisamy M;

Polydimethylsiloxane (PDMS) and poly(3,4-ethylene dioxythiophene):poly(4-styrene-sulfonate) (PEDOT:PSS) composites were tested to determine their suitability for charging small-scale batteries in conjunction with a piezoelectric actuator as an energy harvester. Two different PEDOT:PSS patterns (zigzag and serpentine) were tested, and the maximum DC voltag ...

Article GUID: 40283259


A dual-functional nanogold tablet as a plasmonic and nanozyme sensor for point-of-care applications

Author(s): Sadiq Z; Safiabadi Tali SH; Mansouri M; Jahanshahi-Anbuhi S;

Point-of-care (POC) devices provide on-site disease diagnosis, particularly in resource-limited settings. Despite considerable progress in POC testing, the availability of commercial devices remains limited, primarily due to challenges in detection sensitivity and portability. Furthermore, advancements in existing POC devices are essential to better meet ...

Article GUID: 40177386


Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research

Author(s): Smith EE; Phillips NA; Feldman HH; Borrie M; Ganesh A; Henri-Bhargava A; Desmarais P; Frank A; Badhwar A; Barlow L; Bartha R; Best S; Bethell J; Bhangu J; Black SE; Bocti C; Bronskill SE; Burhan AM; Calon F; Camicioli R; Campbell B; Coll ...

Lecanemab and donanemab are monoclonal antibody therapies that remove amyloid-beta from the brain. They are the first therapies that alter a fundamental mechanism, amyloid-beta deposition, in Alzheimer disease (AD). To inform Canadian decisions on approval and use of these drugs, the Canadian Con ...

Article GUID: 39893139


Author Correction: Typical and extreme weather datasets for studying the resilience of buildings to climate change and heatwaves

Author(s): Machard A; Salvati A; P Tootkaboni M; Gaur A; Zou J; Wang LL; Baba F; Ge H; Bre F; Bozonnet E; Corrado V; Luo X; Levinson R; Lee SH; Hong T; Salles Olinger M; Machado RMES; da Guarda ELA; Veiga RK; Lamberts R; Afshari A; Ramon D; Ngoc Dung Ngo H; Sengupta A; Breesch H; Heijmans N; Deltour J; Kubo ...

No abstract available

Article GUID: 39814748


Amphiphilicity of Tetraazaporphyrins Containing Four Terminal Carboxylic Acid and Four Alkyl Groups Promotes Face-On Orientation in Langmuir Films

Author(s): Alinia Z; Abdulhamied E; Selmani S; Miclette Lamarche R; Eichhorn SH; DeWolf CE;

Control over the orientation of polycyclic aromatic dyes in thin films is paramount to tailoring their optical, electronic, and mechanical properties. Their supramolecular assembly in films is tuned here by converting the macrocyclic dyes to large amphiphiles. Two octaalkythio-substituted tetraazaporphyrins (TAPs) with one 5-carboxypentyl and one pentyl o ...

Article GUID: 39623767


Infants' Social Evaluation of Helpers and Hinderers: A Large-Scale, Multi-Lab, Coordinated Replication Study

Author(s): Lucca K; Yuen F; Wang Y; Alessandroni N; Allison O; Alvarez M; Axelsson EL; Baumer J; Baumgartner HA; Bertels J; Bhavsar M; Byers-Heinlein K; Capelier-Mourguy A; Chijiiwa H; Chin CS; Christner N; Cirelli LK; Corbit J; Daum MM; Doan T; Dr ...

Evaluating whether someone's behavior is praiseworthy or blameworthy is a fundamental human trait. A seminal study by Hamlin and colleagues in 2007 suggested that the ability to form social evaluations based on third-party interactions emerges within the first year of life: infants preferred ...

Article GUID: 39600132


Core charge of imidazolium annulated triphenylene derivatives induces discotic columnar mesomorphism

Author(s): Chen S; Taing H; Ahmida M; He HY; Carr A; Muchall HM; Eichhorn SH;

Thermotropic ionic liquid crystals have remained a relatively little studied group of materials despite their many potential applications as anisotropic ionic liquids and charge (ion and electron/hole) transporting materials. Particularly rare are core charged discotic liquid crystals because their synthesis is usually more involved, and their molecular d ...

Article GUID: 39315415


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