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Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial

Author(s): Liu-Ambrose T; Falck RS; Dao E; Crockett RA; Barha CK; Silva NCBS; Alkeridy WA; Best JR; Hsiung GR; Field TS; Madden KM; Davis JC; Ten Brinke LF; Tam RC;

Introduction: It is unknown whether progressive resistance training (PRT) improves cognitive function in adults with cerebral small vessel disease and mild cognitive impairment (i.e., subcortical vascular cognitive impairment [SVCI]). Methods: We conducted a 12-month randomized trial comparing P ...

Article GUID: 41795685


Developing Topics

Author(s): Silva NCBS; Stein RG; Gu Y; Hsu CL; Tam RC; Salluzzi M; McCreary CR; Alkeridy WA; Lam K; MacKay AL; Kolind S; Cossette B; Griffith LE; Hogan DB; McMillan JM; Raina P; Smith EE; Liu-Ambrose T;

Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative agent of COVID-19 and has infected >700 million persons worldwide. Individuals infected with SARS-CoV-2 are at risk for cognitive decline and at higher risk of dementia compared with those diagnosed with oth ...

Article GUID: 41434542


Public Health

Author(s): Silva NCBS; Balbim GM; Stein RG; Gu Y; Tam RC; Dao E; Alkeridy WA; Kramer AF; Liu-Ambrose T;

Background: Physical activity is associated with higher myelin content in older individuals with cerebral small vessel disease (CSVD), a condition marked by demyelination. However, potential mechanisms underlying these associations remain understudied. High-density lipoprotein (HDL) is involved i ...

Article GUID: 41435075


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