Author(s): Brancheriau CR; Larocque K; Schick G; Tountas I; Perlman A; Piekny A;

Cytokinesis, the final step of cell division, relies on ingression of a precisely positioned actomyosin ring. Chromatin-associated Ran-GTP fine-tunes ring position, although the mechanism remains unclear. We hypothesize that depletion of Ran-GTP between segregating chromosomes leads to equatorial enrichment of importins, promoting recruitment of the scaff ...

Article GUID: 42225064

Author(s): Bairagi K; Shamekhi M; Tountas I; Letourneau N; Peslherbe GH; Piekny A; Oh JK;

The development of stimuli-responsive amphiphilic block copolymers and their nanoassemblies/nanogels integrated with degradable covalent chemistry undergoing chemical transitions has been extensively explored as a promising platform for tumor-targeting controlled/enhanced drug delivery. The conjugate aromatic imine bond is unique in responding to acidic p ...

Article GUID: 40637173