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Auditory processing up to cortex is maintained during sleep spindles

Author(s): Jourde HR; Coffey EBJ;

Sleep spindles are transient 11-16 Hz brain oscillations generated by thalamocortical circuits. Their role in memory consolidation is well established, but how they play a role in sleep continuity and protection of memory consolidation against interference is unclear. One theory posits that spindles or a neural refractory period following their offset act ...

Article GUID: 39588317


Examining Dimensionality and Item-Quality of the Eating Disorder Examination Questionnaire in Individuals With Eating Disorders Using Item Response Theory Analysis

Author(s): Dufour R; Steiger H; Booij L;

Objective: The Eating Disorder Examination Questionnaire (EDE-Q) is a widely-used measure of eating-disorder symptoms. However, inconsistent replication of the subscale structure raises concern about validity. To provide a rigorous test of the EDE-Q's dimensionality and item-quality, we applied modern and classical test theory approaches to data obtai ...

Article GUID: 39548958


Exploring the Qualitative Experiences of Administering and Participating in Remote Research via Telephone Using the Montreal Cognitive Assessment-Blind: Cross-Sectional Study of Older Adults

Author(s): Dumassais S; Grewal KS; Aubin G; O' Connell M; Phillips NA; Wittich W;

Background: The COVID-19 pandemic caused a drastic shift in the practice of research and clinical services. It has been noted that cognition measured via in-person versus remote methods differ substantially, and it is possible that subjective and experiential differences exist between modalities. Objective: The aim of the study is to explore the percepti ...

Article GUID: 39546346


Effects of Cognition-based and Affect-based Trust Attitudes on Trust Intentions

Author(s): Gill H; Vreeker-Williamson E; Hing LS; Cassidy SA; Boies K;

Despite decades of research on trust in the workplace, researchers continue to struggle with fundamental questions regarding the conceptualization and measurement of organizational trust. To help clarify this construct, we revisit established trust definitions (Mayer et al. Academy of Management Review, 20(3), 709-734, Mayer et al., Academy of Management ...

Article GUID: 39507389


On the nature, predictors, and outcomes of work passion profiles: A generalisability study across distinct types of employees

Author(s): Gillet N; Morin AJS; Brault S; Becker M; Verbeke I;

Thus far, little research has adopted a person-centred approach to investigate the nature of work passion profiles. As a result, our understanding of the most commonly occurring combinations of harmonious passion (HP) and obsessive passion (OP) in the workplace remains limited. To achieve a more refined understanding of the nature of these work passion pr ...

Article GUID: 39499627


The effectiveness and acceptability of formal versus informal mindfulness among university students with and without recent self-injury: A randomized controlled trial

Author(s): Petrovic J; Mettler J; Böke BN; Rogers MA; Hamza CA; Bloom E; Di Genova L; Romano V; Heath NL;

Mindfulness instruction comprising both formal (FM) and informal (IM) mindfulness practice is increasingly offered to university students. FM involves sustaining attention on thoughts, emotions and bodily sensations through structured practices, while IM involves incorporating mindfulness into da ...

Article GUID: 39489621


A guide to exploratory structural equation modeling (ESEM) and bifactor-ESEM in body image research

Author(s): Swami V; Maïano C; Morin AJS;

Traditionally, assessments of factor validity of body image instruments have relied on exploratory or confirmatory factor analysis. However, the emergence of exploratory structural equation modeling (ESEM), a resurgence of interest in bifactor models, and the ability to combine both models (bifactor-ESEM) is beginning to shape the future of body image res ...

Article GUID: 39492241


Prediction of depressive symptoms in young adults by polygenic score and childhood maltreatment: Results from a population-based birth cohort

Author(s): Scardera S; Geoffroy MC; Langevin R; Perret LC; Collin-Vézina D; Voronin I; Gouin JP; Meng X; Boivin M; Ouellet-Morin I;

Childhood maltreatment is linked with later depressive symptoms, but not every maltreated child will experience symptoms later in life. Therefore, we investigate whether genetic predisposition for depression (i.e., polygenic score for depression, PGSDEP) modifies the association between maltreatm ...

Article GUID: 39465601


Cell Fate Dynamics Reconstruction Identifies TPT1 and PTPRZ1 Feedback Loops as Master Regulators of Differentiation in Pediatric Glioblastoma-Immune Cell Networks

Author(s): Abicumaran Uthamacumaran

Pediatric glioblastoma is a complex dynamical disease that is difficult to treat due to its multiple adaptive behaviors driven largely by phenotypic plasticity. Integrated data science and network theory pipelines offer novel approaches to studying glioblastoma cell fate dynamics, particularly phenotypic transitions over time. Here we used various single- ...

Article GUID: 39420135


Update and validation of the Beliefs about Losing Control Inventory-II (BALCI-II): a psychometric investigation

Author(s): Kelly-Turner K; Radomsky AS;

The Beliefs about Losing Control Inventory (BALCI) was developed to assess negative beliefs about losing control in obsessive-compulsive disorder (OCD). Since its creation, research and theoretical work support negative beliefs about losing control as a potential transdiagnostic construct. The present study revised and expanded the original BALCI to be mo ...

Article GUID: 39373713


Attention, working memory, and inhibitory control in aging: Comparing amateur singers, instrumentalists, and active controls

Author(s): Joyal M; Sicard A; Penhune V; Jackson PL; Tremblay P;

Despite the ubiquity of musical activities, little is known about the specificity of their association with executive functions. In this cross-sectional study, we examined this relationship as a function of age. Our main hypotheses were that executive functions would decline in older age, that this relationship would be reduced in singers and instrumental ...

Article GUID: 39367878


Microglial senescence in neurodegeneration: Insights, implications, and therapeutic opportunities

Author(s): Samuel Olajide T; Oyerinde TO; Omotosho OI; Okeowo OM; Olajide OJ; Ijomone OM;

The existing literature on neurodegenerative diseases (NDDs) reveals a common pathological feature: the accumulation of misfolded proteins. However, the heterogeneity in disease onset mechanisms and the specific brain regions affected complicates the understanding of the diverse clinical manifestations of individual NDDs. Dementia, a hallmark symptom acro ...

Article GUID: 39364217


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