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Sexually dimorphic role of circadian clock genes in alcohol drinking behavior

Author(s): Nuria de Zavalia

Sex differences in alcohol use and abuse are pervasive and carry important implications for the prevention and treatment of alcohol use disorder (AUD), yet insight into underlying sexually dimorphic mechanisms is limited. Growing experimental and clinical evidence points to an important influence of circadian rhythms and circadian clock genes in the contr ...

Article GUID: 36184679


Potential epigenetic mechanisms in psychotherapy: a pilot study on DNA methylation and mentalization change in borderline personality disorder

Author(s): Quevedo Y; Booij L; Herrera L; Hernández C; Jiménez JP;

Genetic and early environmental factors are interwoven in the etiology of Borderline Personality Disorder (BPD). Epigenetic mechanisms offer the molecular machinery to adapt to environmental conditions. There are gaps in the knowledge about how epigenetic mechanisms are involved in the effects of early affective environment, development of BPD, and psycho ...

Article GUID: 36171872


The role of progesterone in memory bias during spatial navigation in females

Author(s): Eamonn L Gomez-Perales

Rats can use several memory systems to navigate a maze toward a reward. Two of these are place memory and response memory and female rats can be biased to predominantly use one over another. Both progesterone and estrogens have been shown to alter memory bias. Although the effects of estrogens have been well documented, the effects of progesterone remain ...

Article GUID: 36165431


Processing visual ambiguity in fractal patterns: Pareidolia as a sign of creativity

Author(s): Pepin AB; Harel Y; O' Byrne J; Mageau G; Dietrich A; Jerbi K;

Creativity is a highly valued and beneficial skill that empirical research typically probes using "divergent thinking" (DT) tasks such as problem solving and novel idea generation. Here, in contrast, we examine the perceptual aspect of creativity by asking whether creative individuals are more likely to perceive recognizable forms in ambiguous stimuli -a ...

Article GUID: 36164655


Atorvastatin lowers serum calcium levels in lithium-users: results from a randomized controlled trial

Author(s): Soh JF; Bodenstein K; Yu OHY; Linnaranta O; Renaud S; Mahdanian A; Su CL; Mucsi I; Mulsant B; Herrmann N; Rajji T; Beaulieu S; Sekhon H; Rej S;

Background: Although lithium is considered the gold-standard treatment for bipolar disorder (BD), it is associated with a variety of major endocrine and metabolic side effects, including parathyroid hormone (PTH) dependent hypercalcemia. Aside from surgery and medication discontinuation, there ar ...

Article GUID: 36153583


Always Saying the Wrong Thing: Negative Beliefs About Losing Control Cause Symptoms of Social Anxiety

Author(s): Kelly-Turner K; Radomsky AS;

Background: Individuals with social anxiety disorder (SAD) often report a fear that they will lose control of their emotions or report intense, unpleasant thoughts or images of uncontrollably humiliating themselves in social situations. These fears and associated beliefs that one is likely to lose control may underlie the anxiety and/or cognitive biases ( ...

Article GUID: 36117751


DNA methylation as a mediator in the association between prenatal maternal stress and child mental health outcomes: Current state of knowledge

Author(s): Azar N; Booij L;

Background: Prenatal maternal stress is increasingly recognized as a risk factor for offspring mental health challenges. DNA methylation may be a mechanism, but few studies directly tested mediation. These few integrative studies are reviewed along with studies from three research areas: prenatal maternal stress and child mental health, prenatal maternal ...

Article GUID: 36113690


The fear of losing control

Author(s): Adam S Radomsky

Although a great deal of research has focused on various aspects of control and their relations to psychopathology, new insights and therapeutic potential could be revealed through an examination and perhaps emphasis on fears of losing control. Although elements of control-related beliefs and phenomena have been highlighted in association with obsessive-c ...

Article GUID: 36113905


Reliability and validity of the Japanese version of Pain Disability Index

Author(s): Yamada K; Mibu A; Kogo S; Sullivan M; Nishigami T;

This study evaluated the reliability and validity of a Japanese version of Pain Disability Index (PDI). Analyses were conducted on a 7-item version (PDI-J) and a 5-item (PDI-5-J version of the PDI). Using a web-based survey system, we recruited 300 individuals with chronic low back pain (lasting =3 months) and 300 individuals with chronic daily headache ( ...

Article GUID: 36094940


The effects of walking in nature on negative and positive affect in adult psychiatric outpatients with major depressive disorder: A randomized-controlled study

Author(s): Watkins-Martin K; Bolani D; Richard-Devantoy S; Pennestri MH; Malboeuf-Hurtubise C; Philippe F; Guindon J; Gouin JP; Ouellet-Morin I; Geoffroy MC;

Background: While walking in nature has been shown to improve affect in adults from the community to a greater extent than walking in urban settings, it is unknown whether such benefits apply to individuals suffering from depression. Using a parallel group design, this randomized controlled trial ...

Article GUID: 36058362


Quebec-based Parents' Attitudes Towards Childhood Multilingualism: Evaluative Dimensions and Potential Predictors

Author(s): Kircher R; Quirk E; Brouillard M; Ahooja A; Ballinger S; Polka L; Byers-Heinlein K;

This is the first large-scale, quantitative study of the evaluative dimensions and potential predictors of Quebec-based parents' attitudes towards childhood multilingualism. Such attitudes are assumed to constitute a determinant of parental language choices, and thereby influence children's multilingual development. The newly-developed Attitudes t ...

Article GUID: 36051630


Predicting emotion perception abilities for cochlear implant users

Author(s): Paquette S; Deroche MLD; Goffi-Gomez MV; Hoshino ACH; Lehmann A;

Objective: In daily life, failure to perceive emotional expressions can result in maladjusted behaviour. For cochlear implant users, perceiving emotional cues in sounds remains challenging, and the factors explaining the variability in patients' sensitivity to emotions are currently poorly understood. Understanding how these factors r ...

Article GUID: 36047767


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