Author(s): Lay BPP; Esber GR; Iordanova MD;

Adaptive behavior depends on a dynamic balance between acquisition and extinction memories. Male and female rodents differ in extinction learning rates, suggestion potential sex-based differences in this balance. In males, deletion of extinction-recruited neurons in the central nucleus (CN) of the amygdala impairs extinction retrieval, shifting behavior t ...

Article GUID: 40925675

Author(s): Wardell JD; Farrelly KN; Moore A; Fox N; Coelho SG; Cunningham JA; O' Connor RM; Hendershot CS;

Background: This study examined motivational pathways between internalizing symptoms (i.e., depression, anxiety, stress) and simultaneous alcohol and cannabis use among young adults. Methods: Participants (N = 151; 64% female, Mean age = 22.07) completed baseline questionnaires assessing interna ...

Article GUID: 40923811

Author(s): Paquette V; Danyluk AJ; Gilbert W; Houle SA; Lavoie P; Eltanoukhi R; Morin AJS;

Young adults use a combination of coping strategies to deal with challenges. Yet, limited research has focused on these combinations, as they differ across different profiles of youth and their implications during the major life transitions of emerging adulthood. Addressing this gap, the present longitudinal person-centered study assesses the nature, stab ...

Article GUID: 40924344

Author(s): Coupal P; Zhang Y; Deroche M;

While blink analysis was traditionally conducted within vision research, recent studies suggest that blinks might reflect a more general cognitive strategy for resource allocation, including with auditory tasks, but its use within the fields of Audiology or Psychoacoustics remains scarce and its interpretation largely speculative. It is hypothesized that ...

Article GUID: 40910460

Author(s): Bastien L; Cho S; Petrovic J; Khoury B; Bloom E; Heath N;

University students are reporting high levels of stress that interfere with their academic performance and daily functioning. In response, higher education institutions have increasingly implemented digital, self-guided stress management resources to provide students with accessible mental health support. While these interventions show promise for improvi ...

Article GUID: 40895119

Author(s): Dufour R; Breton É; Côté SM; Dubois L; Vitaro F; Boivin M; Tremblay RE; Booij L;

Objective: Several studies have shown that maladaptive eating behaviors in childhood predict greater risk for eating disorders in adolescence. Whether or not maladaptive eating behaviors could represent developmental risk factors for a larger spectrum of psychopathologies is unknown. This study described longitudinal trajectories of overeating and picky e ...

Article GUID: 40883733

Author(s): Abicumaran Uthamacumaran

Advancements in AI-powered systems medicine have revolutionized biomarker discovery through emergent and explainable features. By use of complex network dynamics and graph-based machine learning, we identified critical determinants of lineage-specific plasticity across the single-cell transcriptomics of pediatric high-grade glioma (pHGGs) subtypes: IDHWT ...

Article GUID: 40848317

Author(s): Moore C; Donhauser PW; Klein D; Byers-Heinlein K;

The remarkable human capacity for bilingual and multilingual acquisition raises fundamental questions about how the brain develops efficient systems for processing multiple languages. In this study, we used neural network models trained on natural speech input to examine how these efficient representations emerge. Our models show that multiple phonologica ...

Article GUID: 40828024

Author(s): Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda- ...

The PREVENT-AD is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now been followed annually for more than 12 years [median follow-up 8.0 years,SD 3.1]. Multimodal ...

Article GUID: 40778177

Author(s): Carter F; Hobishi H; Chapman CA;

The parasubiculum is a component of the hippocampal formation that projects to the entorhinal cortex and plays an important role in spatial navigation. Dopamine has marked effects on excitatory synaptic transmission in the hippocampus and entorhinal cortex, and the present study investigated the effects of dopamine on evoked field excitatory postsynaptic ...

Article GUID: 40818632

Author(s): Khoshzad M; Maïano C; Morin AJS; Aimé A;

Intuitive eating is an adaptive eating style that could help explain part of the relation between affect and eating behaviors. However, research in this area remains limited. The objectives of this study are twofold. First, we examine the relation between affect, disordered eating attitudes and behaviors (DEABs), and orthorexia nervosa (ON). Second, we in ...

Article GUID: 40723751

Author(s): Stark Z; Johnson AP;

Dyslexia is a neurobiological disorder characterized by persistent difficulties in reading, writing and spelling. Studying adults with dyslexia is challenging due to diverse experiences, varying ages of diagnosis and potential comorbidities. This study utilized a mixed-method approach to explore how the timing and occurrence of a dyslexia diagnosis influe ...

Article GUID: 40702374