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Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial

Author(s): Liu-Ambrose T; Falck RS; Dao E; Crockett RA; Barha CK; Silva NCBS; Alkeridy WA; Best JR; Hsiung GR; Field TS; Madden KM; Davis JC; Ten Brinke LF; Tam RC;

Introduction: It is unknown whether progressive resistance training (PRT) improves cognitive function in adults with cerebral small vessel disease and mild cognitive impairment (i.e., subcortical vascular cognitive impairment [SVCI]). Methods: We conducted a 12-month randomized trial comparing P ...

Article GUID: 41795685


Efficient self-supervised Barlow Twins from limited tissue slide cohorts for colonic pathology diagnostics

Author(s): Notton C; Sharma V; Quoc-Huy Trinh V; Chen L; Xu M; Varma S; Hosseini MS;

Colorectal cancer (CRC) is one of the few cancers that have an established dysplasia-carcinoma sequence that benefits from screening. Everyone over 50 years of age in Canada is eligible for CRC screening. About 20% of those people will undergo a biopsy for a pre-neoplastic polyp and, in many cases, multiple polyps. As such, these polyp biopsies make up th ...

Article GUID: 41793844


Season and city shape urban bioaerosol composition beyond vegetation and socioeconomic gradients

Author(s): Poirier S; Rondeau-Leclaire J; Faticov M; Roy A; Lajeunesse G; Lucier JF; Tardif S; Kembel SW; Ziter C; Laprise C; Paquette A; Girard C; Laforest-Lapointe I;

Urban vegetation varies with socio-economic gradients, as lower-income neighborhoods often host sparser and less diverse green spaces. This disparity may affect respiratory health by influencing exposure to bioaerosols. Understanding the characteristics of this aerobiome could help anticipate ris ...

Article GUID: 41785576


Blending Poly(dimethylsiloxane) with Poly(lactic acid) Using Polyhydroxyurethane Additives

Author(s): Younes GR; Heli B; Ajji A;

This work blends polydimethylsiloxane (PDMS) with poly-(lactic acid) (PLA) using polyhydroxyurethane (PHU) structures. The PHU is synthesized from mannitol biscarbonate and a short-chain PDMS-based diamine. The main objectives are, first, to explore the application of the PDMS-based PHU as an additive for PLA and, second, to enhance the flexibility and hy ...

Article GUID: 41783236


The effect of postoperative rehabilitation on outcomes in patients with degenerative cervical myelopathy (DCM): A systematic review

Author(s): Montpetit C; Kobaisi A; Lantz JM; Chauhan RV; Anderson DB; Fortin M;

Introduction: Degenerative cervical myelopathy (DCM) is the leading cause of adult spinal cord dysfunction, often requiring surgery. However, the role of postoperative rehabilitation in optimizing patient outcomes remains unclear. Research question: What are the effects of postoperative rehabilitation on clinical outcomes following DCM surgery? Material ...

Article GUID: 41693706


The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial

Author(s): Downey RI; Petersen BJ; Mohanathas N; Campos JL; Montero-Odasso M; Bherer L; Pichora-Fuller MK; Bray NW; Burhan AM; Camicioli R; Fraser S; Liu-Ambrose T; Lussier M; Middleton LE; Pieruccini-Faria F; Phillips NA; Li KZH;

Background: Hearing loss is one of the largest potentially modifiable risk factors for dementia and is linked with poor cognitive-motor dual-task performance (e.g., walking while performing a cognitive task). Hearing loss is more prevalent and severe in males, whereas dementia is more prevalent i ...

Article GUID: 41694460


ADPv2: A hierarchical histological tissue type-annotated dataset for potential biomarker discovery of colorectal disease

Author(s): Yang Z; Li K; Ramandi SG; Brassard P; Khellaf A; Trinh VQ; Zhang J; Chen L; Rowsell C; Varma S; Plataniotis K; Hosseini MS;

Computational pathology (CPath) leverages histopathology images to enhance diagnostic precision and reproducibility in clinical pathology. However, publicly available datasets for CPath that are annotated with extensive histological tissue type (HTT) taxonomies at a granular level remain scarce d ...

Article GUID: 41658283


Surgery resident pain knowledge and perceptions: gaps and implications for medical training in Canada

Author(s): Burcheri AJ; Galvin CR; Piché N; Frett MJ; Alschuler K; Alberts NM;

Introduction: Healthcare provider pain knowledge is critical in surgical settings, where effective pain management plays a key role in the prevention of chronic postsurgical pain. Despite this, little is known about the pain training and knowledge of surgical residents. Objective: To comprehensively assess Canadian surgery residents' knowledge and at ...

Article GUID: 41635476


Impact of COVID-19 on incidence and trends of adverse events among hospitalised patients in Calgary, Canada: a retrospective chart review study

Author(s): Wu G; Eastwood CA; Cheligeer C; Southern DA; Zeng Y; Ghali WA; Bakal JA; Boussat B; Flemons W; Forster A; Xu Y; Quan H;

Background: While the incidence of hospital adverse events appeared to be declining before 2019, the COVID-19 pandemic may have changed its course. This study aimed to evaluate adverse event incidence rates and trends during the pandemic and analyse differences in patient outcomes. Methods: This ...

Article GUID: 41592994


Psychosocial Outcomes Reported in Randomized Behavioral Intervention Trials for Children and Adolescents with Overweight and Obesity: A Scoping Review

Author(s): Sacco S; Booij L; Kwok C; Carrière K; Hall K; Baluyot TC; Forouhar V; Côté M; Pietrasik M; Jebeile H; Ball GDC; Johnston BC; Alberga AS;

Background: Many children and adolescents with overweight or obesity experience negative psychosocial health consequences. Systematic reviews show that behavioral interventions can help improve specific psychosocial outcomes. This scoping review aims to identify and map the different types of psy ...

Article GUID: 41601261


Biological sex and bilingualism: Its impact on risk and resilience for dementia

Author(s): Calvo N; Phillips N; Bialystok E; Einstein G;

Introduction: The relationship between biological sex, considered a risk factor for Alzheimer's disease (AD), and bilingualism, a resilience factor, is unclear. We assessed this relationship in 335 individuals with mild cognitive impairment (MCI) in a Canadian cohort. Methods: We used univariate analysis and structural equation modelling to study the ...

Article GUID: 41573422


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