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The Characteristics and Criteria Used to Define Persisting Symptoms in Children with Concussion: A Scoping Review

Author(s): Iuliano SG; Coupal J; Bacon S; Teel EF;

The objective was to characterize the definitions and criteria used to determine persisting symptoms after concussion in children. This scoping review followed a five-step framework. Four databases (PubMed, Scopus, PsychInfo, and Web of Science) were searched using the concepts of concussion, children, and persisting symptoms. Articles were included if th ...

Article GUID: 41943482


From periodontitis to neurodegeneration: Can probiotics modulate the em P. gingivalis /em -amyloid pathway in Alzheimer s disease?

Author(s): Sharif-Askari Z; Atoui K; El Zein W; Rizk M; Sharif Askari E;

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the gradual destruction of cognitive and behavioral functions. Despite the continuous research efforts, there is still no cure for this disease. In recent years, researchers have investigated Porphyromonas gingivalis (P. gingivalis) as a potential cause of AD. P. gingivalis-lipo ...

Article GUID: 41940869


A Fully Virtual Graded Exertion Test Is Safe and Feasible in Symptomatic and Asymptomatic Children With Concussion

Author(s): Coupal J; Shabanova D; Gagnon I; Grilli L; Beaulieu C; Teel E;

Context: Current graded exertion tests (GXTs) for concussion management require specialized equipment and in-person supervision. The Montreal Virtual Exertion (MOVE) protocol is a telehealth-compatible GXT but has been tested only in pseudo-virtual conditions. Objective: To determine the safety and feasibility of the MOVE protocol when administered remot ...

Article GUID: 41816309


Characteristics and associated weight-loss responses to the diabetes prevention program for adults with acquired brain injury: secondary analysis of two randomized control trials

Author(s): Quilico E; Alrawi S; Callender L; McShan E; Park S; Bennett M; Driver S;

Objective: Examine the association and temporal relationship between weight-loss and participant characteristics in a sample of community-dwelling adults with acquired brain injury (ABI), including cerebral vascular accident (CVA) and traumatic brain injury (TBI). Design: Secondary data analysis of a wait-list control assessor-blinded randomized control ...

Article GUID: 41610975


Updated Status of Physical Activity Research for People With Traumatic Brain Injury

Author(s): Quilico EL; Driver SJ;

Objective: To update the status of physical activity research after moderate-to-severe traumatic brain injury (msTBI) by systematically reviewing empirical studies across health-related fields with the behavioral epidemiological framework to identify evidence-based interventions and inform future recommendations. The last review of physical activity resea ...

Article GUID: 41606762


Preexisting Mental Health Disorders Are Associated With Acute Clinical Presentation and Longitudinal Recovery Trajectories in Adolescents With Concussion

Author(s): Iuliano SG; Gagnon IJ; Iverson GL; Cook NE; Zemek R; Teel EF;

This secondary analysis examined the association between preexisting mental health conditions and clinical recovery trajectories in adolescents with concussion. Adolescents (13-17; n = 1238) completed clinical assessments (Post-Concussion Symptom Inventory [PCSI] =48 hours postinjury; PCSI/ Pediatric Quality of Life [PedsQL] for 3 months) and were categor ...

Article GUID: 41505351


Human short-term memory learning based on dynamic glutamate levels and oscillatory activities: concurrent metabolic and electrophysiological studies using event-related functional-MRS and EEG modalities

Author(s): Mohammadi H; Zargaran SJ; Khajehpour H; Adibi I; Rahimiforoushani A; Karimi S; Serej ND; Alam NR;

Short-term memory (STM) temporarily stores sensory information, critical for synaptic plasticity, memory, and learning, and is regulated by the glutamate-gated NMDA receptor. While the frontal and parieto-occipital cortices have been implicated in STM, the electrochemical dynamics of the right he ...

Article GUID: 41171530


The longitudinal effects of global and regional brain measurements on cognitive abilities

Author(s): Hosseininasabnajar F; Kakinami L;

Loss of brain tissues and cognitive abilities are natural processes of aging, but longitudinal studies are limited. We explored the longitudinal association between global and regional brain measures with cognitive abilities among individuals with normal cognitive status, mild cognitive impairment, and Alzheimer's Disease, including those with stable ...

Article GUID: 40739300


Neurophysiological effects of targeting sleep spindles with closed-loop auditory stimulation

Author(s): Jourde HR; Sobral M; Beltrame G; Coffey EBJ;

Sleep spindles are neural events unique to nonrapid eye movement sleep that play key roles in memory reactivation and consolidation. However, much of the evidence for their function remains correlational rather than causal. Closed-loop brain stimulation uses real-time monitoring of neural events (often via electroencephalography; EEG) to deliver precise a ...

Article GUID: 40626105


Personalizing brain stimulation: continual learning for sleep spindle detection

Author(s): Sobral M; Jourde HR; Marjani Bajestani SE; Coffey EBJ; Beltrame G;

Personalized closed-loop brain stimulation, in which algorithms used to detect neural events adapt to a user's unique neural characteristics, may be crucial to enable optimized and consistent stimulation quality for both fundamental research and clinical applications. Precise stimulation of sleep spindles-transient patterns of brain activity that occu ...

Article GUID: 40609549


Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia

Author(s): Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Da ...

Study objectives: Insomnia in older adults is associated with widespread benzodiazepine (BZD) and benzodiazepine receptor agonist (BZRA) use, despite evidence that chronic use disrupts sleep regulation and cognition. Little is known about BZD/BZRA effects on NREM slow oscillations (SO), spindles ...

Article GUID: 40570297


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