Author(s): Gamache I; Fagbemi K; Harnois-Leblanc S; Greenwood CMT; Henderson M; Van Hulst A; Timpson NJ; Manousaki D;

Aims/hypothesis: Dysglycaemia in youth results from complex interactions between genetic and environmental factors, yet their individual and combined contributions remain unclear. We aimed to: (1) evaluate the predictive performance of polygenic risk scores (PRSs) for glycaemic traits from childh ...

Article GUID: 41986816

Author(s): Beaulieu J; Yates MC; Fraser DJ; Cristescu ME; Derry AM;

Anthropogenic activities have led to an unprecedented crisis in freshwater biodiversity loss. The capacity to monitor the abundance of wild populations is critical to conserving biodiversity, but conventional physical specimen collection methods are invasive, costly and labour-intensive. Environmental DNA (eDNA) offers a promising alternative, being easy ...

Article GUID: 41913704

Author(s): Hajiaghayi M; Gholizadeh F; Rahbari N; Emamnia N; Shih SCC; Darlington PJ;

Introduction: Cancers often drive T cells toward an exhausted state characterized by impaired cytotoxicity and upregulation of inhibitory receptors (PD-1, TIM-3, CD38) and transcriptional regulators (TOX, NFATc1). Repeated stimulation in vitro is used to model this process, reflecting chronic antigen exposure in the tumor microenvironment. Stress-derived ...

Article GUID: 41906691

Author(s): Velchovska N; Khelifa R;

As global food systems face mounting sustainability pressures, insects are gaining attention as a promising alternative protein source. Yet, entomophagy remains culturally unfamiliar or stigmatized in many Western countries, including Canada. This study investigates attitudes toward insect consumption among 252 adult visitors to the Montreal Insectarium, ...

Article GUID: 41565845

Author(s): Seralini GE; Jungers G; Andersen A; Antoniou M; Aschner M; Bacon MH; Bertrand M; Bohn T; Bonfleur ML; Bücking E; Defarge N; Djemil R; Domingo JL; Douzelet J; Fagan J; Fournier T; Garcia JLY; Gil S; Hervé-Gruyer P; Hilbeck A; Hilty L; Hub ...

We propose a new paradigm, as toxicology currently lacks the proper perspective. From the 1950s to the 1970s, at least one-third of all toxicological testing in the United States, including for chemicals and drugs, was misleading scientists, and this worldwide issue persists today. Moreover, petr ...

Article GUID: 41551494

Author(s): Rezaei-Moghaddam K; Fatemi M; Ghafouri M; Golkarfard M;

Entrepreneurship is a key driver of empowerment, particularly in rural areas, as it creates opportunities for self-sufficiency and sustainable development. It enables individuals to overcome barriers, build capacity, and engage in participatory activities that foster economic and social growth. This study aimed to analyze entrepreneurship and the empowerm ...

Article GUID: 41290906

Author(s): Pan S; Wang X; Guo T; An H; Guo Y; Chen Z; Lian J; Guo J;

Inefficient electron transfer is one of the main challenges in practical denitrification applications. To address this issue, a novel ternary mediator functional material (Mxene@Fe-TA) was successfully synthesized, which exhibited pseudocapacitive properties to facilitate electron mediation and distribution. Batch experiments revealed that 50 mg/L MXene@F ...

Article GUID: 41043789

Author(s): Li Z; Chen R; Xing C; Zhong G; Zhang X; Jones KC; Zhu Y;

Organophosphate esters (OPEs) have emerged as a global environmental and health concern due to their persistent, bioaccumulative, and toxic (PBT) properties. Recently, their precursors-organophosphite antioxidants (OPAs)-and transformation products, which may exhibit greater persistence and toxicity, have gained attention as critical contributors to OPE-r ...

Article GUID: 40845576

Author(s): Yu J; Wu B; Peng C; Wentzell J; Wheeler MJ; Osagu JO; Zhang X; Li L; Abbatt JPD; Liggio J;

Bisphenol A (BPA) is a common endocrine disruptor widely found in commercial products. Despite negative human health effects, its usage is not fully banned worldwide with ongoing human exposure from sources including dust, aerosol particles, and surfaces. Although attention has been paid to the a ...

Article GUID: 40569786

Author(s): Iravani R; Biagi M; Laforest S; Lee K; Isaacman L; Chen Z; An C;

There is growing concern regarding the environmental protection of shorelines in Canadian Indigenous communities, as these regions face increasing threats from pollution and environmental degradation. This review examines various types of pollution affecting coastal Indigenous communities, such as oil spills, plastic waste, industrial runoff, and other co ...

Article GUID: 40554913

Author(s): Wang Z; Huang G; Chen Z; An C;

With the rapid growth of electric vehicle adoption, the demand for lithium-ion batteries has surged, highlighting the importance of understanding the associated risks, particularly in non-application stages such as transportation, storage, assembly, and disposal. This review explores the types and causes of lithium-ion battery accidents, categorizing them ...

Article GUID: 40223134