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Intraperitoneal Administration of Cardiolipin Enhances Mitochondrial Respiration in Skeletal Muscle of Male Mice

Author(s): Laplante A; Bergdahl A;

Purpose: Cardiolipin is a phospholipid located in the inner mitochondrial membrane and is released following myocardial ischemia-reperfusion injury. While cardiolipin has documented effects in several tissues, its impact on skeletal muscle function and mitochondrial respiration remains unclear. The purpose of this study was to investigate the effects of e ...

Article GUID: 42046821


Intervention development to reduce sedentary behaviour among adults: a qualitative investigation using the Behaviour Change Wheel

Author(s): Harsanyi H; Slot N; Parkinson R; Morielli AR; Jeyapalan A; Holmes E; Flynn S; Campbell T; Quan H; Zeng Y; Yang J; Singh S; Vena J; Biddle S; Friedenreich CM; Yang L;

Article GUID: 42015269


Interrogating the agency of non-profit labour market intermediaries: Casting light on shadow spaces through an institutional-relational view

Author(s): Rantisi NM; Henaway M; Leslie D;

In a context of government cutbacks, non-profit labour-market intermediaries are assuming a more significant role in efforts to combat precarious employment. Yet such organizations are still subject to state funding regimes, regulations, oversight and neoliberal logics. As such, some scholars argue that they constitute "shadow state" spaces. In ...

Article GUID: 42005907


Quantitative modeling of nanoplastic accumulation from single-use water bottles: exposure scenarios and tissue concentration estimates

Author(s): Sajedi S; An C;

The widespread use of single-use plastic (SUP) water bottles has raised growing concerns about chronic human exposure to nanoplastics (NPs). This study presents a quantitative assessment of NP accumulation in human tissues resulting from the long-term consumption of SUP water bottles. Using survey-derived consumption data and the Human Exposure and Absorp ...

Article GUID: 42007012


Widespread exposure to GLP-1RAs and weight loss-related discourse: Considering potential public health implications

Author(s): Côté M; Ramos Salas X; Carrière K; Alberga AS;

Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs), are approved for the treatment of type 2 diabetes, obesity, and related conditions, and have demonstrated significant benefits for individuals with these conditions. However, in recent years, public interest and demand for GLP-1RAs-often driven by media, social media ...

Article GUID: 41986775


Nature vs nurture of glucose homeostasis trajectories in children from the ALSPAC study

Author(s): Gamache I; Fagbemi K; Harnois-Leblanc S; Greenwood CMT; Henderson M; Van Hulst A; Timpson NJ; Manousaki D;

Aims/hypothesis: Dysglycaemia in youth results from complex interactions between genetic and environmental factors, yet their individual and combined contributions remain unclear. We aimed to: (1) evaluate the predictive performance of polygenic risk scores (PRSs) for glycaemic traits from childh ...

Article GUID: 41986816


Deep learning-based femoral reconstruction from intraoperative point clouds for enhanced knee arthroplasty registration

Author(s): Kafian Safari M; Mirzae M; Gheflati B; Sharifzade M; Zuhars J; Rottoo S; Rivaz H;

Purpose: Computer- and robotic-assisted technologies improve total knee arthroplasty (TKA) through intraoperative bone registration. However, limited bone exposure restricts point collection to the distal femur, omitting key geometric features and reducing registration accuracy and the surgical outcomes. Methods: We introduce a deep learning-based method ...

Article GUID: 41984365


Reliability and Validity of Risk Assessment Tools for Violent Extremism: A Systematic Review

Author(s): Brouillette-Alarie S; Hassan G; Varela W; Danis E; Ousman S; Madriaza P; Pauls IL; Kilinc D; Pickup D; Pelzer R; Borokhovski E;

Assessment of the risk of engaging in a violent radicalization/extremism trajectory has evolved quickly in the last 10 years. Guided by what has been achieved in psychology and criminology, scholars from the field of preventing violent extremism (PVE) have tried to import key lessons from violenc ...

Article GUID: 41978672


BON in a Box: An Open and Collaborative Platform for Biodiversity Monitoring, Indicator Calculation, and Reporting

Author(s): Griffith J; Lord JM; Catchen MD; Arce-Plata MI; Blanchet FG; Chandramohan M; Diaz-Corzo MC; Gravel D; Gutiérrez C; Helfenstein IS; Hoban S; Kass JM; Laikre L; Larocque G; Leigh DM; Leung B; Mastretta-Yanes A; Millette KL; Berbeo MAM; Ngu ...

The Convention on Biological Diversity's Kunming-Montreal Global Biodiversity Framework (GBF) sets ambitious goals to protect and restore biodiversity. It includes a monitoring framework that mandates countries to track progress toward these goals using indicators that summarize biodiversity ...

Article GUID: 41971256


Conversation cards for pregnancy: a protocol for a multi-method study

Author(s): Alberga AS; Forouhar V; Lurye V; Adamo KB; Avery S; Ball GDC; Farnesi BC; Gaudet L; Nagpal TS; Piccinini-Vallis H; Ramos Salas X; Rhodes RE; Vallis M; Cook J; Graham TM; Stanworth-Belleville K; Cohen TR;

Background: Conversations regarding health behaviours, mental health, and socioeconomic contexts are recommended during prenatal visits to optimize maternal and fetal health outcomes. This study was designed to develop and evaluate the acceptability of a clinical dialogue tool called Conversation ...

Article GUID: 41964085


Editorial: Social influences on ontogenetic development

Author(s): Rodriguez Buritica JM; van den Bos W; Eppinger B; Ciranka SK;

Article GUID: 41947957


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