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On the Implementation of a Compact Vertical DC Biasing Network with Significantly Reduced RF Components for Phase-Shifter-Free Beam Steering

Author(s): Zheng S; Qian B; Chen X; Kishk AA;

Dense direct-current (DC) bias routing and numerous radio-frequency (RF) choke inductors pose major challenges to the practical implementation of phase-shifter-free beam steering using PIN-controlled phase switching. To address this issue, a compact vertical DC biasing network is proposed, in which most DC bias lines are routed beneath the ground plane. T ...

Article GUID: 42281100


From Rapid Reviews to Rapid Living Evidence Synthesis: Lessons From COVID-19 Vaccine Effectiveness Reviews for Canadian Public Health Decision-Making

Author(s): Wu N; Joyal-Desmarais K; Linkins LA; Flórez ID; Bacon SL;

Background: The COVID-19 pandemic demanded evidence synthesis approaches that could keep pace with rapidly evolving science and urgent policy needs. Rapid reviews and living evidence syntheses (LES) emerged as critical methodological responses, yet limited guidance exists for teams undertaking such work, particularly regarding the operational challenges o ...

Article GUID: 42282099


Enhanced co-removal of nitrate and tetracycline from wastewater by iron-nitrogen-doped carbon: synergistic role of pyridinic nitrogen and iron

Author(s): Yang W; Wang X; Li H; Liu W; Chen Z; Ren B; Guo T; Guo J;

Co-pollution of nitrate and tetracycline (TC) poses a critical barrier to efficient biological treatment due to impaired electron transfer, diminished microbial metabolic activity, and disrupted community structure. To address this challenge, this study synthesized an iron-nitrogen-doped carbon material (Fe-NC) featuring electron-withdrawing pyridinic nit ...

Article GUID: 42259450


Predictions From Evolutionary Theory for Urban Environments

Author(s): MacPherson A; Caizergues AE; Savary P; Xu K; Messer PW; Akbar MN; Fortin MJ; Holt RD; Hoi AG; Mideo N; Ness R; Peres-Neto PR; Santangelo JS; Johnson MTJ;

Urbanization drives rapid and extreme environmental change, profoundly shaping the ecology and evolution of populations. In this Perspective, we call for the integration and development of evolutionary theory and empirical research through collaboration between theoretical and experimental biolog ...

Article GUID: 42253486


em In silico /em rational investigation of C-terminal arginine-containing white Lupin ( em Lupinus albus /em ) protein-derived peptides as arginase inhibitors

Author(s): Chukwuejim S; Fatoki TH; Aluko RE;

Arginase is a binuclear manganese metalloenzyme that modulates L-arginine availability and downstream metabolic pathways. It was hypothesized that C-terminal arginine-containing peptides generated through simulated gastrointestinal digestion of white lupin (Lupinus albus) proteins would exhibit arginase inhibitory activity. To test this hypothesis, integr ...

Article GUID: 42232067


How effective have Canadian national parks been at preventing landscape fragmentation?

Author(s): Freeman-Cole CE; Jaeger JAG;

While landscape connectivity is an important focus of Canada's conservation goals, Canadian national parks are vulnerable to habitat loss, the breaking-up of habitat patches, and a reduction in their connectivity to surrounding ecosystems. This study measured landscape fragmentation in 43 Canadian national parks and control areas throughout their hist ...

Article GUID: 42228295


The Effect of Aortic Regurgitation on Left Ventricular Flow Dynamics Assessed by 4D-Flow MRI

Author(s): Abdallah W; Darwish A; Garcia J; Kadem L;

Background: Aortic regurgitation (AR) alters normal blood flow patterns in the left ventricle (LV), affecting diastolic filling dynamics, and is commonly quantified by the regurgitant fraction (RF). However, conventional diagnostic methods have notable limitations, prompting growing interest in four-dimensional flow magnetic resonance imaging (4D-flow MRI ...

Article GUID: 42228301


Importin-β1 functions as a chromatin sensor to position the contractile ring for cytokinesis

Author(s): Brancheriau CR; Larocque K; Schick G; Tountas I; Perlman A; Piekny A;

Cytokinesis, the final step of cell division, relies on ingression of a precisely positioned actomyosin ring. Chromatin-associated Ran-GTP fine-tunes ring position, although the mechanism remains unclear. We hypothesize that depletion of Ran-GTP between segregating chromosomes leads to equatorial enrichment of importins, promoting recruitment of the scaff ...

Article GUID: 42225064


Multilingualism and cognitive reserve in older adults with, or at risk for, Alzheimer s disease: Evidence from resting-state functional connectivity

Author(s): Coulter K; Dash T; Best T; Grant N; Ansaldo AI; Phillips NA;

Speaking more than one language is hypothesized to lead to greater brain resilience in aging and Alzheimer's disease, resulting in a delay in the symptom onset of Alzheimer's disease. While previous research has used structural neuroimaging measures to explore the neural underpinnings of this protective effect, few studies have used functional bra ...

Article GUID: 42208339


Practices to Reduce Stigma and Discrimination Towards Older Transitional Housing Clients

Author(s): Canham SL; Richardson LR; Aaenson-Fletcher J; Weldrick R; Walsh CA;

Homelessness remains an enduring social issue, in part, due to the stigmatization of and discrimination toward people experiencing homelessness, known as homeism. Despite extant research on the topic, little is known about how homeism, enacted through stigmatization and discrimination, may occur within transitional housing programs or among older people e ...

Article GUID: 42184413


Isatin-pyridine oxime hybrids as potential reactivators of A-242-inhibited acetylcholinesterase

Author(s): Pinto AMV; Bhattacharyya D; da Silva MCJ; Kitagawa DAS; Dos Santos MC; Cavalcante SFA; Islam ST; LaPlante SR; Forgione P; Diz JSF; França TCC;

Three new isatin-pyridine-2-oxime hybrids (AM01-03) were synthesized and experimentally evaluated as reactivators of acetylcholinesterase (AChE) inhibited by a surrogate of the nerve agent A-242, in comparison with their 4-oxime isomers previously reported by our research group. Furthermore, the ...

Article GUID: 42171685


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