Author(s): Sajedi S; An C;

The widespread use of single-use plastic (SUP) water bottles has raised growing concerns about chronic human exposure to nanoplastics (NPs). This study presents a quantitative assessment of NP accumulation in human tissues resulting from the long-term consumption of SUP water bottles. Using survey-derived consumption data and the Human Exposure and Absorp ...

Article GUID: 42007012

Author(s): Wang Z; Su Y; Lu Z; An C;

Maritime transport is a major contributor to greenhouse gas (GHG) emissions, and ports play a critical role in shaping regional and national decarbonization pathways. This study develops a comprehensive framework to quantify both offshore and onshore GHG emissions associated with port activities and applies it to the Vancouver Fraser Port Authority (VFPA) ...

Article GUID: 41925888

Author(s): Fukue M; Lechowicz Z; Mulligan CN; Takeuchi S; Takeuchi H;

As a response to aging of cultured urease-producing microorganisms, the blending method was examined to obtain the required carbonate production amount using the apparent viability (Rcv) based on previous research. As a result, a significantly higher carbonate content than the amount of CaCl2 2H2O used was produced. Since this trend has been obtained in p ...

Article GUID: 41900613

Author(s): McAnulty C; Lavoie P; Cyr S; Lavin P; Elkrief L; Richard-Devantoy S; Rizkallah E; Lespérance P; Gamin N; Lembke A; Jutras-Aswad D; Greenway K; Garel N;

Background: Alcohol use disorder and treatment-resistant depression (TRD) often co-occur, presenting a major clinical challenge with limited effective treatments. However, ketamine produces rapid antidepressant effects and has shown promise in reducing alcohol use, and acceptance and commitment t ...

Article GUID: 41857871

Author(s): Baez A; Hazel K; Guertin Z; Fong E; Manus MM; Kaloyannis A; Helfield B;

Adoptive cell transfer (ACT)-based immunotherapy has emerged as a transformative approach for treating cancer, offering durable responses through the ex vivo expansion and reinfusion of antigen-specific immune cells. Despite remarkable clinical successes, most notably with chimeric antigen receptor (CAR)-T cell therapy, ACT remains limited by severe toxic ...

Article GUID: 41748028

Author(s): Wardell JD; Farrelly KN; Moore A; Fox N; Coelho SG; Cunningham JA; O' Connor RM; Hendershot CS;

Background: This study examined motivational pathways between internalizing symptoms (i.e., depression, anxiety, stress) and simultaneous alcohol and cannabis use among young adults. Methods: Participants (N = 151; 64% female, Mean age = 22.07) completed baseline questionnaires assessing interna ...

Article GUID: 40923811

Author(s): Bastien L; Cho S; Petrovic J; Khoury B; Bloom E; Heath N;

University students are reporting high levels of stress that interfere with their academic performance and daily functioning. In response, higher education institutions have increasingly implemented digital, self-guided stress management resources to provide students with accessible mental health support. While these interventions show promise for improvi ...

Article GUID: 40895119

Author(s): Francavilla R; Chattopadhyaya B; Damo Kamda JL; Jadhav V; Kourrich S; Michaud JL; Di Cristo G;

SYNGAP1 haploinsufficiency-related intellectual disability (SYNGAP1-ID) is characterized by moderate to severe ID, generalized epilepsy, autism spectrum disorder, sensory processing dysfunction, and other behavioral abnormalities. While numerous studies have highlighted a role of Syngap1 in corti ...

Article GUID: 40810392

Author(s): Richmond IC; Paulauskas MA; Padvaiskas E; Gonzàlez Sinisterra LC; Hutt-Taylor K; Robitaille AL; Ziter CD;

Cities are temporally dynamic ecosystems that experience continuous redevelopment over time. Urban parks, which provide critical benefits to resident wellbeing, are developed on different land-use types and contain natural elements that are susceptible to the effects of historical decision-making ...

Article GUID: 40761092

Author(s): Corran C; Morin AJS; Hendershot CS; O' Connor RM;

Background: Alcohol use and problems increase during adolescence and peak in early adulthood. Tension reduction theory points to anxiety sensitivity as a risk factor for alcohol misuse, and the theory of planned behavior suggests that injunctive norms (i.e., perceived approval of risky drinking) may be central to this risk trajectory. Methods: This study ...

Article GUID: 40667852

Author(s): Memari E; Singh D; Alkins R; Helfield B;

Cellular immunotherapy remains hindered in the context of solid tumors due to the immunosuppressive microenvironment, in which key endothelial cell adhesion molecules (CAM) are suppressed. Microbubble-mediated focused ultrasound is being explored for targeted immunotherapy and can exert local shear stress upon neighboring endothelial cells. However, fluid ...

Article GUID: 40657183