Keyword search (3,099 papers available)


Paraspinal Muscle Changes in Individuals with and without Chronic Low Back Pain over a 4-Month Period: A Longitudinal MRI Study

Author(s): Anstruther M; Sean M; Tétreault P; Fortin M;

Background and Objectives: Previous research has shown associations between atrophy and fatty infiltration of the lumbar paraspinal musculature and low back pain (LBP). However, few studies have examined longitudinal changes in healthy controls and individu...

Article GUID: 38541216

MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics

Author(s): Tremblay SA; Alasmar Z; Pirhadi A; Carbonell F; Iturria-Medina Y; Gauthier CJ; Steele CJ;

Multivariate approaches have recently gained in popularity to address the physiological unspecificity of neuroimaging metrics and to better characterize the complexity of biological processes underlying behavior. However, commonly used approaches are biased...

Article GUID: 38463982

The assessment of paraspinal muscle epimuscular fat in participants with and without low back pain: A case-control study

Author(s): Rosenstein B; Burdick J; Roussac A; Rye M; Naghdi N; Valentin S; Licka T; Sean M; Tétreault P; Elliott J; Fortin M;...

It remains unclear whether paraspinal muscle fatty infiltration in low back pain (LBP) is i) solely intramuscular, ii) is lying outside the epimysium between the muscle and fascial plane (epimuscul...

Article GUID: 38280825

Consistency of electrical source imaging in presurgical evaluation of epilepsy across different vigilance states

Author(s): Avigdor T; Abdallah C; Afnan J; Cai Z; Rammal S; Grova C; Frauscher B;

Objective: The use of electrical source imaging (ESI) in assessing the source of interictal epileptic discharges (IEDs) is gaining increasing popularity in presurgical work-up of patients with drug-resistant focal epilepsy. While vigilance affects the abili...

Article GUID: 38217279

NSF evaluation of gadolinium biodistribution in renally impaired rats: Using novel metabolic Gd2O3 nanoparticles coated with β-cyclodextrin (Gd2O3@PCD) in MR molecular imaging

Author(s): Ashouri H; Alam NR; Khoobi M; Haghgoo S; Rasouli Z; Gholami M;

The use of conventional gadolinium(Gd)-based contrast agents in magnetic resonance imaging (MRI) poses a significant risk of Nephrogenic Systemic Fibrosis (NSF) syndrome in patients with impaired renal function (grades 4 and 5). To address this issue, a new...

Article GUID: 38215955

Decreased long-range temporal correlations in the resting-state functional magentic resonance imaging blood-oxygen-level-dependent signal reflect motor sequence learning up to 2 weeks following training

Author(s): Jäger AP; Bailey A; Huntenburg JM; Tardif CL; Villringer A; Gauthier CJ; Nikulin V; Bazin PL; Steele CJ;...

Decreased long-range temporal correlations (LRTC) in brain signals can be used to measure cognitive effort during task execution. Here, we examined how learning a motor sequence affects long-range ...

Article GUID: 38124341

Effect of aquatic exercise versus standard care on paraspinal and gluteal muscles morphology in individuals with chronic low back pain: a randomized controlled trial protocol

Author(s): Rosenstein B; Montpetit C; Vaillancourt N; Dover G; Khalini-Mahani N; Weiss C; Papula LA; Melek A; Fortin M;...

Background: Low back pain (LBP) is one of the most disabling diseases and a major health issue. Despite the evidence of a link between paraspinal and gluteal muscle dysfunction and LBP, it is unkno...

Article GUID: 38110922

Prioritizing a research agenda on built environments and physical activity: a twin panel Delphi consensus process with researchers and knowledge users

Author(s): Prince SA; Lang JJ; de Groh M; Badland H; Barnett A; Littlejohns LB; Brandon NC; Butler GP; Casu G; Cerin E; Colley RC; de Lannoy L; Demchen...

Background: The growth of urban dwelling populations globally has led to rapid increases of research and policy initiatives addressing associations between the built environment an...

Article GUID: 38062460

Perceptions of self-monitoring dietary intake according to a plate-based approach: A qualitative study

Author(s): Kheirmandparizi M; Gouin JP; Bouchaud CC; Kebbe M; Bergeron C; Madani Civi R; Rhodes RE; Farnesi BC; Bouguila N; Conklin AI; Lear SA; Cohen ...

Dietary self-monitoring is a behaviour change technique used to help elicit and sustain dietary changes over time. Current dietary self-monitoring tools focus primarily on itemizing foods and count...

Article GUID: 38015899


Title:How cerebral cortex protects itself from interictal spikes: The alpha/beta inhibition mechanism
Authors:Pellegrino GHedrich TSziklas VLina JMGrova CKobayashi E
Link:https://pubmed.ncbi.nlm.nih.gov/34002916/
DOI:10.1002/hbm.25422
Category:
PMID:34002916
Dept Affiliation: PERFORM
1 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
2 Department of Biomedical Engineering, Multimodal Functional Imaging Lab, McGill University, Montreal, Quebec, Canada.
3 Departement de Genie Electrique, Ecole de Technologie Superieure, Montreal, Quebec, Canada.
4 Centre De Recherches En Mathematiques, Montreal, Quebec, Canada.
5 Department of Physics and PERFORM Centre, Concordia University, Montreal, Quebec, Canada.

Description:

Interactions between interictal epileptiform discharges (IEDs) and distant cortical regions subserve potential effects on cognition of patients with focal epilepsy. We hypothesize that "healthy" brain areas at a distance from the epileptic focus may respond to the interference of IEDs by generating inhibitory alpha and beta oscillations. We predict that more prominent alpha-beta oscillations can be found in patients with less impaired neurocognitive profile. We performed a source imaging magnetoencephalography study, including 41 focal epilepsy patients: 21 with frontal lobe epilepsy (FLE) and 20 with mesial temporal lobe epilepsy. We investigated the effect of anterior (i.e., frontal and temporal) IEDs on the oscillatory pattern over posterior head regions. We compared cortical oscillations (5-80 Hz) temporally linked to 3,749 IEDs (1,945 frontal and 1,803 temporal) versus an equal number of IED-free segments. We correlated results from IED triggered oscillations to global neurocognitive performance. Only frontal IEDs triggered alpha-beta oscillations over posterior head regions. IEDs with higher amplitude triggered alpha-beta oscillations of higher magnitude. The intensity of posterior head region alpha-beta oscillations significantly correlated with a better neuropsychological profile. Our study demonstrated that cerebral cortex protects itself from IEDs with generation of inhibitory alpha-beta oscillations at distant cortical regions. The association of more prominent oscillations with a better cognitive status suggests that this mechanism might play a role in determining the cognitive resilience in patients with FLE.