Keyword search (3,095 papers available)


MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics

Author(s): Tremblay SA; Alasmar Z; Pirhadi A; Carbonell F; Iturria-Medina Y; Gauthier CJ; Steele CJ;

Multivariate approaches have recently gained in popularity to address the physiological unspecificity of neuroimaging metrics and to better characterize the complexity of biological processes underlying behavior. However, commonly used approaches are biased...

Article GUID: 38463982

The assessment of paraspinal muscle epimuscular fat in participants with and without low back pain: A case-control study

Author(s): Rosenstein B; Burdick J; Roussac A; Rye M; Naghdi N; Valentin S; Licka T; Sean M; Tétreault P; Elliott J; Fortin M;...

It remains unclear whether paraspinal muscle fatty infiltration in low back pain (LBP) is i) solely intramuscular, ii) is lying outside the epimysium between the muscle and fascial plane (epimuscul...

Article GUID: 38280825

Consistency of electrical source imaging in presurgical evaluation of epilepsy across different vigilance states

Author(s): Avigdor T; Abdallah C; Afnan J; Cai Z; Rammal S; Grova C; Frauscher B;

Objective: The use of electrical source imaging (ESI) in assessing the source of interictal epileptic discharges (IEDs) is gaining increasing popularity in presurgical work-up of patients with drug-resistant focal epilepsy. While vigilance affects the abili...

Article GUID: 38217279

NSF evaluation of gadolinium biodistribution in renally impaired rats: Using novel metabolic Gd2O3 nanoparticles coated with β-cyclodextrin (Gd2O3@PCD) in MR molecular imaging

Author(s): Ashouri H; Alam NR; Khoobi M; Haghgoo S; Rasouli Z; Gholami M;

The use of conventional gadolinium(Gd)-based contrast agents in magnetic resonance imaging (MRI) poses a significant risk of Nephrogenic Systemic Fibrosis (NSF) syndrome in patients with impaired renal function (grades 4 and 5). To address this issue, a new...

Article GUID: 38215955

Decreased long-range temporal correlations in the resting-state functional magentic resonance imaging blood-oxygen-level-dependent signal reflect motor sequence learning up to 2 weeks following training

Author(s): Jäger AP; Bailey A; Huntenburg JM; Tardif CL; Villringer A; Gauthier CJ; Nikulin V; Bazin PL; Steele CJ;...

Decreased long-range temporal correlations (LRTC) in brain signals can be used to measure cognitive effort during task execution. Here, we examined how learning a motor sequence affects long-range ...

Article GUID: 38124341

Effect of aquatic exercise versus standard care on paraspinal and gluteal muscles morphology in individuals with chronic low back pain: a randomized controlled trial protocol

Author(s): Rosenstein B; Montpetit C; Vaillancourt N; Dover G; Khalini-Mahani N; Weiss C; Papula LA; Melek A; Fortin M;...

Background: Low back pain (LBP) is one of the most disabling diseases and a major health issue. Despite the evidence of a link between paraspinal and gluteal muscle dysfunction and LBP, it is unkno...

Article GUID: 38110922

Prioritizing a research agenda on built environments and physical activity: a twin panel Delphi consensus process with researchers and knowledge users

Author(s): Prince SA; Lang JJ; de Groh M; Badland H; Barnett A; Littlejohns LB; Brandon NC; Butler GP; Casu G; Cerin E; Colley RC; de Lannoy L; Demchen...

Background: The growth of urban dwelling populations globally has led to rapid increases of research and policy initiatives addressing associations between the built environment an...

Article GUID: 38062460

Perceptions of self-monitoring dietary intake according to a plate-based approach: A qualitative study

Author(s): Kheirmandparizi M; Gouin JP; Bouchaud CC; Kebbe M; Bergeron C; Madani Civi R; Rhodes RE; Farnesi BC; Bouguila N; Conklin AI; Lear SA; Cohen ...

Dietary self-monitoring is a behaviour change technique used to help elicit and sustain dietary changes over time. Current dietary self-monitoring tools focus primarily on itemizing foods and count...

Article GUID: 38015899

Brain PET Imaging in Small Animals: Tracer Formulation, Data Acquisition, Image Reconstruction, and Data Analysis

Author(s): Bdair H; Kang MS; Ottoy J; Aliaga A; Kunach P; Singleton TA; Blinder S; Soucy JP; Leyton M; Rosa-Neto P; Kostikov A;...

Positron emission tomography (PET) is a noninvasive functional imaging modality that involves in vivo detection of spatiotemporal changes in the binding of radioactive pharmaceuticals (a.k.a. PET t...

Article GUID: 38006502


Title:The effects of combined motor control and isolated extensor strengthening versus general exercise on paraspinal muscle morphology and function in patients with chronic low back pain: a randomised controlled trial protocol
Authors:Fortin MRye MRoussac ANaghdi NMacedo LGDover GElliott JMDeMont RWeber MHPepin V
Link:https://pubmed.ncbi.nlm.nih.gov/34022854/
DOI:10.1186/s12891-021-04346-x
Category:
PMID:34022854
Dept Affiliation: PERFORM
1 Department Health Kinesiology and Applied Physiology, Concordia University, 7141 Sherbrooke Street W, SP-165.29, Montreal, Quebec, H4B 1R6, Canada. maryse.fortin@concordia.ca.
2 PERFORM Centre, Concordia University, Montreal, Quebec, Canada. maryse.fortin@concordia.ca.
3 Centre de Recherche Interdisciplinaire en Réadaptation (CRIR), Montreal, Quebec, Canada. maryse.fortin@concordia.ca.
4 Department Health Kinesiology and Applied Physiology, Concordia University, 7141 Sherbrooke Street W, SP-165.29, Montreal, Quebec, H4B 1R6, Canada.
5 School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
6 PERFORM Centre, Concordia University, Montreal, Quebec, Canada.
7 Centre de Recherche Interdisciplinaire en Réadaptation (CRIR), Montreal, Quebec, Canada.

Description:

Background: Exercise is a common approach for the management of patients with chronic non-specific low back pain (LBP). However, there is no clear mechanistic evidence or consensus on what type of exercise is more effective than others. While considerable evidence suggests a link between lumbar muscle health (e.g., atrophy and fatty infiltration) with functional deficits, it is unknown whether exercises targeting the lumbar spine can lead to noticeable improvements in muscle health and functional outcomes. The primary aim of this study is to compare the effect of combined motor control and isolated strengthening lumbar exercises (MC + ILEX) versus a general exercise group (GE) on multifidus muscle morphology (size and composition). Secondary aims include assessing the effect of the interventions on overall paraspinal muscle health, pain and disability, as well as psychological factors as possible effect modifiers.

Methods: A total of 50 participants with chronic non-specific LBP and moderate to severe disability, aged between 18 and 60, will be recruited from the local orthopaedic clinics and university community. Participants will be randomised (1:1) to either the MC + ILEX or GE group. Participants will undergo 24 individually supervised exercise sessions over a 12-week period. The primary outcome will be multifidus morphology (atrophy) and composition (fatty infiltration). Secondary outcomes will be muscle function (e.g., % thickness change during contraction), morphology, lumbar extension strength, pain intensity and disability. Potential treatment effect modifiers including maladaptive cognitions (fear of movement, catastrophizing), anxiety, depression, physical activity, and sleep quality will also be assessed. All measurements will be obtained at baseline, 6-week and 12-week; self-reported outcomes will also be collected at 24-week. Between-subjects repeated measure analysis of variance will be used to examine the changes in paraspinal muscle morphology over the different time points. Linear mixed models will be used to assess whether baseline scores can modify the response to the exercise therapy treatment.

Discussion: The results of this study will help clarify which of these two common interventions promote better results in terms of overall paraspinal muscle heath, back pain, disability and psychological factors in adults with chronic LBP.

Trial registration: NTCT04257253 , registered prospectively on February 5, 2020.