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Validating MEG estimated resting-state connectome with intracranial EEG

Author(s): Afnan J; Cai Z; Lina JM; Abdallah C; Pellegrino G; Arcara G; Khajehpour H; Frauscher B; Gotman J; Grova C;...

Magnetoencephalography (MEG) is widely used for studying resting-state brain connectivity. However, MEG source imaging is ill posed and has limited spatial resolution. This introduces source-leakag...

Article GUID: 40161991
Overweight and obesity in early childhood and obesity at 10 years of age: a comparison of World Health Organization definitions

Author(s): Van Hulst A; Zheng S; Argiropoulos N; Ybarra M; Ball GDC; Kakinami L;

The World Health Organization recommends using + 2 SD of body mass index z-score (zBMI) to define overweight/obesity (OWO) in children ages 2 to 5 years whereas + 1 SD is used as cut-point from 5 years onwards. Empirical evidence for using different cut-poi...

Article GUID: 40140102
The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies

Author(s): Avigdor T; Ren G; Abdallah C; Dubeau F; Grova C; Frauscher B;

Morning awakening is part of everyday life. Surprisingly, information remains scarce on its underlying neurophysiological correlates. Here simultaneous polysomnography and stereo-electroencephalography recordings from 18 patients are used to assess the spec...

Article GUID: 40126936
Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility

Author(s): Potvin-Jutras Z; Intzandt B; Mohammadi H; Liu P; Chen JJ; Gauthier CJ;

Cerebrovascular reactivity (CVR) and cerebral pulsatility (CP) are important indicators of cerebrovascular health, which are associated with physical activity (PA). While sex differences influence the impact of PA on cerebrovascular health, sex-specific eff...

Article GUID: 40079560
Comparison of Combined Motor Control Training and Isolated Extensor Strengthening Versus General Exercise on Lumbar Paraspinal Muscle Health and Associations With Patient-Reported Outcome Measures in Chronic Low Back Pain Patients: A Randomized Controlled Trial

Author(s): Rosenstein B; Rye M; Roussac A; Naghdi N; Macedo LG; Elliott J; DeMont R; Weber MH; Pepin V; Dover G; Fortin M;...

Study DesignProspective Randomized Controlled Trial.ObjectivesTo investigate the effect of combined motor control and isolated lumbar strengthening exercise (MC + ILEX) vs general exercise (GE) on ...

Article GUID: 40066720
Combating childhood overweight and obesity: The role of Olympic Movement and bodily movement

Author(s): Tam BT; Wan K; Santosa S; Cai Z;

With over 420 million children (aged 0-19 years) worldwide living with overweight or obesity, the "obesity epidemic" or "globesity" is a defining public health challenge of this generation. While significant efforts have been made to address...

Article GUID: 39991475
A database of magnetic resonance imaging-transcranial ultrasound co-registration

Author(s): Alizadeh M; Collins DL; Kersten-Oertel M; Xiao Y;

Purpose: As a portable and cost-effective imaging modality with better accessibility than Magnetic Resonance Imaging (MRI), transcranial sonography (TCS) has demonstrated its flexibility and potential utility in various clinical diagnostic applications, inc...

Article GUID: 39920905
Sex differences in the metabolism of glucose and fatty acids by adipose tissue and skeletal muscle in humans

Author(s): Costa DN; Santosa S; Jensen MD;

Adult males and females have markedly different body composition, energy expenditure, and have different degrees of risk for metabolic diseases. A major aspect of metabolic regulation involves the appropriate storage and disposal of glucose and fatty acids....

Article GUID: 39869194
Dialogue mechanisms between astrocytic and neuronal networks: A whole-brain modelling approach

Author(s): Ali OBK; Vidal A; Grova C; Benali H;

Astrocytes critically shape whole-brain structure and function by forming extensive gap junctional networks that intimately and actively interact with neurons. Despite their importance, existing computational models of whole-brain activity ignore the roles ...

Article GUID: 39804928
Title:The effects of a 12-week combined motor control exercise and isolated lumbar extension intervention on lumbar multifidus muscle stiffness in individuals with chronic low back pain
Authors:Tornblom A,  Naghdi N,  Rye M,  Montpetit C,  Fortin M, 
Link:https://pubmed.ncbi.nlm.nih.gov/39258113/
DOI:10.3389/fphys.2024.1336544
Category:
PMID:39258113
Dept Affiliation: SOH
1 Department of Health, Kinesiology and Applied Physiology, Concordia University, Montreal, QC, Canada.
2 School of Health, Concordia University, Montreal, QC, Canada.

Description:

Introduction: Exercise therapy is the primary endorsed form of conservative treatment for chronic low back pain (LBP). However, there is still conflicting evidence on which exercise intervention is best. While motor control exercise can lead to morphological and functional improvements of lumbar multifidus muscle in individuals with chronic LBP, the effects of exercise prescription on multifidus stiffness assessed via shear wave elastography are still unknown. The primary aim of this study is to determine the effects of a combined motor control and isolated lumbar extension (MC + ILEX) intervention on lumbar multifidus muscle stiffness.

Methods: A total of 25 participants aged 18 to 65 were recruited from local orthopedic clinics and the university community with moderate to severe non-specific chronic LBP. Participants performed a 12-week MC + ILEX intervention program. Stiffness of the lumbar multifidus muscle (primary outcome) at L4 and L5 was obtained at baseline, 6-week, and 12-week using shear wave elastography. Changes in stiffness ratio (e.g., ratio of lumbar multifidus muscle stiffness from rest to contracted) were also assessed at both time points. Pre to post-intervention changes in lumbar multifidus muscle stiffness were assessed using a one-way repeated measure ANOVA.

Results: Following the 12-week intervention, there were no statistically significant changes in lumbar multifidus muscle stiffness at rest on the right side at L4 (p = 0.628) and the left side at L4 and L5 (p = 0.093, p = 0.203), but a statistically significant decrease was observed on the right side at L5 (p = 0.036). There was no change in lumbar multifidus muscle stiffness ratio.

Conclusion: This study provides preliminary evidence to suggest that a 12-week MC + ILEX intervention had minimal effect on lumbar multifidus muscle stiffness in individuals with chronic LBP. Further investigations are needed to confirm our findings and clarify the relationship between muscle stiffness and functional outcomes.