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Colistin heteroresistance, mechanisms, diagnostic methods, and therapeutic options: A review

Author(s): Dehbanipour R; Maleki VTZ; Ghalavand Z;

The heteroresistance phenotype refers to the presence of bacterial subpopulations with reduced antibiotic susceptibility compared with the main population. Mathematical modelling and computer simulations suggest that heteroresistance can lead to negative treatment outcomes and finally, treatment failure. Due to the low frequency and resistance level of re ...

Article GUID: 40949035


Guanidinylated cluster-modified chitosan for wet-strength paper

Author(s): Gu J; Gu Z; Wu B; Xiao S; Zheng S; Chen N; Zhuang J; Liu H; Jia Z; Meng Y; Cui X; Huang L;

Wet-strength resins are fundamentally important for papers as they provide water resistance and wet strength, allowing papers to complete tasks before incurring wet damage. Resins currently in use are primarily petroleum-based substances that pose inherently environmental and health risks due to ...

Article GUID: 40947212


Distributed adaptive fault-tolerant cooperative control for fixed-wing UAVs with actuator faults and input constraints

Author(s): Fu M; Yu Z; Zhang Y;

This paper proposes a distributed fault-tolerant cooperative control framework for multiple fixed-wing UAVs (FUAVs), grounded on a complete six-degrees-of-freedom (6-DOF) nonlinear dynamic model. The architecture integrates position and attitude control, explicitly accounting for actuator faults and multiple input constraints. In the outer loop, an adapti ...

Article GUID: 40946062


Cooperative Schemes for Joint Latency and Energy Consumption Minimization in UAV-MEC Networks

Author(s): Cheng M; He S; Pan Y; Lin M; Zhu WP;

The Internet of Things (IoT) has promoted emerging applications that require massive device collaboration, heavy computation, and stringent latency. Unmanned aerial vehicle (UAV)-assisted mobile edge computing (MEC) systems can provide flexible services for user devices (UDs) with wide coverage. The optimization of both latency and energy consumption rema ...

Article GUID: 40942666


Unraveling glyphosate sequestration: The role of natural organic matter fractions in soil-water contamination and retention

Author(s): Adeola AO; Paramo L; Duarte MP; Fuoco G; Naccache R;

The bioavailability and fate of pesticides in soil are largely influenced by soil's sorption characteristics. Therefore, the adsorption of pesticides, like glyphosate (GBH), onto soil natural organic matter (NOM) was investigated in this study. With the aid of sequential treatment methods of agricultural soil, NOM was modified to yield demineralized m ...

Article GUID: 40939356


The predictive role of olfactory identification on episodic memory and mild cognitive impairment: Results from the CIMA-Q cohort

Author(s): Jobin B; Phillips NA; Frasnelli J; Boller B;

BackgroundOlfactory identification decline is a known early marker of Alzheimer's disease and is already present at the mild cognitive impairment (MCI) stage. While being linked with episodic memory, its predictive value for cognitive performance and distinguishing between clinical stages remains unclear.ObjectiveThis study examined (1) the predictive ...

Article GUID: 40944318


Mechanochemical synthesis of π-conjugated naphthotetrathiophene-based covalent organic frameworks and their post-modification em via /em the Doebner reaction

Author(s): Gohari MH; Ghamari P; Hamzehpoor E; Effaty F; Frišcic T; Perepichka DF;

We report that mechanochemistry enables the synthesis of new p-conjugated covalent organic frameworks (COFs) based on naphthotetrathiophenetetracarbaldehydes 2TTN and 3TTN, expanding the scope of COF structures with two new isomeric tetradentate nodes. While recent studies have explored COF isomerism by varying bidentate linkers to tune electronic propert ...

Article GUID: 40936612


Neurodiversity, Minority Status, and Mental Health: A Quantitative Study on the Experiences of Culturally Diverse University Students in Canada

Author(s): Bayeh R; Ryder AG;

Background: There is community knowledge shared among autistic and other neurodivergent (ND) communities that ND individuals are more likely to share other non-normative identities, along with research demonstrating that ND individuals have worse mental health outcomes than neurotypicals (NTs). The purpose of this study is to assess how co-occurrence of n ...

Article GUID: 40933676


Reduction in reward-driven behaviour depends on the basolateral but not central nucleus of the amygdala in female rats

Author(s): Lay BPP; Esber GR; Iordanova MD;

Adaptive behavior depends on a dynamic balance between acquisition and extinction memories. Male and female rodents differ in extinction learning rates, suggestion potential sex-based differences in this balance. In males, deletion of extinction-recruited neurons in the central nucleus (CN) of the amygdala impairs extinction retrieval, shifting behavior t ...

Article GUID: 40925675


BOLD Long-Range Temporal Correlations Reflect Changes in Language and Depression Across Intensive Aphasia Therapy

Author(s): Jäger AP; Steele CJ; Dreyer FR; Osterloh MR; Sadlon A; Nikulin V; Mohr B; Pulvermüller F;

Background: Intensive language-action therapy treats language deficits and depressive symptoms in chronic poststroke aphasia, yet the underlying neural mechanisms remain underexplored. Long-range temporal correlations (LRTCs) in blood oxygenation level-dependent signals indicate persistence in brain activity patterns and may relate to learning and levels ...

Article GUID: 40927858


Internalizing symptoms are indirectly associated with simultaneous alcohol and cannabis use through specific motives for simultaneous use: A longitudinal study of young adults

Author(s): Wardell JD; Farrelly KN; Moore A; Fox N; Coelho SG; Cunningham JA; O' Connor RM; Hendershot CS;

Background: This study examined motivational pathways between internalizing symptoms (i.e., depression, anxiety, stress) and simultaneous alcohol and cannabis use among young adults. Methods: Participants (N = 151; 64% female, Mean age = 22.07) completed baseline questionnaires assessing interna ...

Article GUID: 40923811


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