Author(s): Paez A; Piñol-Ripoll G; Carnes-Vendrell A; Dakterzada F; Barbé F; Zetterberg H; Dang-Vu TT;

Background and objectives: Sleep-wake dysregulation and elevated CSF orexin have been implicated in Alzheimer disease (AD). Sleep spindles (SPs) and slow oscillations (SOs) are linked to cognition and neurodegeneration; however, their relationship with CSF orexin concentrations in symptomatic AD ...

Article GUID: 42447420

Author(s): Magrill J; Falet JP; Boone E; Luigi M; Arthur I; Asadi P; Frumkin A; Sorin M; Romero JM; Luo J; Johnson N; Eisenberg MJ;

Background: Canadian MD-PhD and Clinician Investigator Program (CIP) pathways both train physician-scientists, yet longitudinal data on graduate research productivity are limited. Methods: We conducted a longitudinal study of McGill University MD-PhD and CIP graduates who completed these program ...

Article GUID: 42446907

Author(s): Storck V; Ponton DE; Lawruk-Desjardins C; Ferriz LM; Leclerc M; Kraemer S; Planas D; Amyot M; Walsh D;

Understanding contaminant dynamics in ecosystems requires considering interactions between habitats-an aspect often overlooked in research. Mercury (Hg) studies typically focus on methylmercury (MeHg) production in sediments, often neglecting the role of biofilms such as periphyton. This study an ...

Article GUID: 42445734

Author(s): Archambault P; Keil M; Muchall HM; Peslherbe GH;

Conformational and configurational states of the sugar-phosphate backbone play an important role in DNA transcriptional and RNA translational events. In particular, the geometric parameters of the sugar ring dictate the degree of pucker, influencing the overall conformational state of the nucleic acid structure and its potential for base pairing and stack ...

Article GUID: 42444611

Author(s): Noor S; Castillo Salazar RA; Girona MM; Despland E;

Wildfires and insect outbreaks are major natural disturbances in boreal forests, and both are intensifying with climate change. Since insects are sensitive bio-indicators, wildfire smoke may alter their role in forest ecosystems. In 2023, wildfires in Eastern Canada caused extreme smoke events, with fine particulate matter (PM2.5) reaching hazardous air q ...

Article GUID: 42443556

Author(s): Chentsova-Dutton YE; Ryder AG;

Singh compellingly describes some psychological factors that shape selection of cultural variants, but his approach gives insufficient attention to how culture shapes psychology. We argue the subjective selection account needs to pay greater attention to the psychological nuances of goal pursuit, cultural shaping of both perceived and " actual" ...

Article GUID: 42439271

Author(s): Yuan S; Zhao Y; Lessard JP; Martin TE; Matthews TJ; Si X;

The species pool is a fundamental concept with the potential to connect ecological and evolutionary processes in community ecology and biogeography. However, current definitions of the concept primarily focus on contemporary ecological processes, ignoring the historical and evolutionary processes that generated the species pool. We propose a phylogenetic ...

Article GUID: 42436076

Author(s): Di Lorenzo B; Camargo Tavares L; Díaz-Muñoz C; Heredia-Fernández F; Bozzarelli I; Esteban Blanco C; Wang Z; Smit RAJ; Loos RJF; Hirbo J; Cox NJ; Straub P; Favé MJ; Awadalla P; Pozdeyev N; Gignoux CR; Gudbjartsson DF; Thorleifsson G; Jons ...

Background: Irritable bowel syndrome (IBS) is a complex disorder of gut-brain interaction, with heterogeneous symptoms, no available biomarkers and limited pathogenetic insight. Objective: To identify genetic risk factors and actionable mechanisms for future clinical translation in IBS. Design: ...

Article GUID: 42425734

Author(s): Retanal F; Bakker EG; Wales E; Bureau JF; LeFevre JA; Osana HP; Skwarchuk SL; Maloney EA;

Do children's perception of their parents' math attitudes contribute to their own math anxiety? From 2023 to 2024, one hundred and six parent (53.8% White, 76.4% Mothers) child (Mage = 8.75, 49.1% White, 54.7% Female) dyads in Canada reported their own math anxiety and children additionally reported their perception of parents' math enjoyment. ...

Article GUID: 42423654

Author(s): Abdallah C; Delaire E; Dascal A; González A; Cai Z; Hedrich T; Khajehpour H; Ikemoto S; Tanaka M; Bernhardt BC; Kobayashi E; Gotman J; Frauscher B; Grova C;

Objective: Accurate presurgical evaluation should assess not only the location but also the spatial extent of epileptic activity relative to the surgical cavity, a practical approximation of the epileptogenic zone. We evaluated how electromagnetic source imaging (EMSI) and hemodynamic responses t ...

Article GUID: 42423621

Author(s): Antal C; de Almeida RG;

We present a new set of English property norms for 260 object concepts based on the standardized Snodgrass and Vanderwart (1980) picture set. For each object, 100 participants provided a basic-level label (dog), a superordinate category (animal), and three features (bark, tail, fur), yielding a dataset of 78,000 features. Our norms differ from other datas ...

Article GUID: 42420648