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Widespread exposure to GLP-1RAs and weight loss-related discourse: Considering potential public health implications

Author(s): Côté M; Ramos Salas X; Carrière K; Alberga AS;

Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs), are approved for the treatment of type 2 diabetes, obesity, and related conditions, and have demonstrated significant benefits for individuals with these conditions. However, in recent years, public interest and demand for GLP-1RAs-often driven by media, social media ...

Article GUID: 41986775


Nature vs nurture of glucose homeostasis trajectories in children from the ALSPAC study

Author(s): Gamache I; Fagbemi K; Harnois-Leblanc S; Greenwood CMT; Henderson M; Van Hulst A; Timpson NJ; Manousaki D;

Aims/hypothesis: Dysglycaemia in youth results from complex interactions between genetic and environmental factors, yet their individual and combined contributions remain unclear. We aimed to: (1) evaluate the predictive performance of polygenic risk scores (PRSs) for glycaemic traits from childh ...

Article GUID: 41986816


Deep learning-based femoral reconstruction from intraoperative point clouds for enhanced knee arthroplasty registration

Author(s): Kafian Safari M; Mirzae M; Gheflati B; Sharifzade M; Zuhars J; Rottoo S; Rivaz H;

Purpose: Computer- and robotic-assisted technologies improve total knee arthroplasty (TKA) through intraoperative bone registration. However, limited bone exposure restricts point collection to the distal femur, omitting key geometric features and reducing registration accuracy and the surgical outcomes. Methods: We introduce a deep learning-based method ...

Article GUID: 41984365


Reliability and Validity of Risk Assessment Tools for Violent Extremism: A Systematic Review

Author(s): Brouillette-Alarie S; Hassan G; Varela W; Danis E; Ousman S; Madriaza P; Pauls IL; Kilinc D; Pickup D; Pelzer R; Borokhovski E;

Assessment of the risk of engaging in a violent radicalization/extremism trajectory has evolved quickly in the last 10 years. Guided by what has been achieved in psychology and criminology, scholars from the field of preventing violent extremism (PVE) have tried to import key lessons from violenc ...

Article GUID: 41978672


BON in a Box: An Open and Collaborative Platform for Biodiversity Monitoring, Indicator Calculation, and Reporting

Author(s): Griffith J; Lord JM; Catchen MD; Arce-Plata MI; Blanchet FG; Chandramohan M; Diaz-Corzo MC; Gravel D; Gutiérrez C; Helfenstein IS; Hoban S; Kass JM; Laikre L; Larocque G; Leigh DM; Leung B; Mastretta-Yanes A; Millette KL; Berbeo MAM; Ngu ...

The Convention on Biological Diversity's Kunming-Montreal Global Biodiversity Framework (GBF) sets ambitious goals to protect and restore biodiversity. It includes a monitoring framework that mandates countries to track progress toward these goals using indicators that summarize biodiversity ...

Article GUID: 41971256


Advancing translational research in binge-eating: Integrating insights from clinical practice into animal models

Author(s): Dufour R; Shalev U; Booij L;

Binge-eating behaviors are key components of several types of eating disorders, yet their etiology remains unclear. Animal models have provided valuable insights by enabling experimentally controlled investigations of biological, behavioral, and environmental factors contributing to eating disorders. This narrative review examines the clinical relevance o ...

Article GUID: 41965343


Microbial fuel cell (MFC)-based biosensor for real-time detection of heavy metals and BTEX contaminants in water

Author(s): Baik JH; Hwang JH; Ryu H; Gomez-Alvarez V; Kim KT; Hyoung Lee W;

This study evaluates a mixed-culture microbial fuel cell (MFC) as a rapid, real-time biosensor for detecting water toxicity caused by heavy metals and benzene, toluene, ethylbenzene, and xylene (BTEX) compounds. A dual-chamber MFC (200 mL) equipped with carbon fiber electrodes was operated with an electroactive biofilm on the anode, and toxicity responses ...

Article GUID: 41962434


Conversation cards for pregnancy: a protocol for a multi-method study

Author(s): Alberga AS; Forouhar V; Lurye V; Adamo KB; Avery S; Ball GDC; Farnesi BC; Gaudet L; Nagpal TS; Piccinini-Vallis H; Ramos Salas X; Rhodes RE; Vallis M; Cook J; Graham TM; Stanworth-Belleville K; Cohen TR;

Background: Conversations regarding health behaviours, mental health, and socioeconomic contexts are recommended during prenatal visits to optimize maternal and fetal health outcomes. This study was designed to develop and evaluate the acceptability of a clinical dialogue tool called Conversation ...

Article GUID: 41964085


Editorial: Social influences on ontogenetic development

Author(s): Rodriguez Buritica JM; van den Bos W; Eppinger B; Ciranka SK;

Article GUID: 41947957


Rethinking Obesity Prevention: A Call for Strategic and Operational Clarity

Author(s): Ramos Salas X; Hussey B; Alberga AS; Kyle T; Small F;

Article GUID: 41945228


Effects of aquatic therapy vs. standard care on gluteal muscle morphology and function in individuals with chronic low back pain: a randomized controlled trial

Author(s): Montpetit C; Vaillancourt N; Rosenstein B; Wesselink EO; Dover G; Weiss C; Papula LA; Melek A; Weber KA; Elliott JM; Fortin M;

Article GUID: 41943153


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