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Atmospheric aging of tire rubber antioxidants forms complex mixtures that trigger inflammation in human macrophages

Author(s): Peng C; Liggio J; Moussa SG; Tang Y; Johannessen C; Zhang X; Zhang Z; Li L; Harner T; Saini A; Hung H; Wentzell J; Wheeler MJ; Dabek-Zlotorzynska E; Yassine M; Liu Q; Tang M; Friel-Bartlett Z; Abdul-Sater AA;

Antioxidants added to tires to prevent degradation have recently been recognized as emerging environmental contaminants. While their acute aquatic toxicity has raised concern, these compounds are also emitted to the atmosphere and can be associated with particulate matter (PM). On PM they can rea ...

Article GUID: 42191547


Bilingual Families Align Their Languages During Naturalistic Interactions: Evidence from Two Bilingual Communities

Author(s): Fibla L; Kosie JE; Tsui RK; Potter CE; Lew-Williams C; Byers-Heinlein K;

Bilingual children learn their languages through rich interactions with caregivers within dynamic family contexts. However, little is known about how families align their two languages to support bilingual acquisition and how this varies across bilingual communities. This study examines language choice alignment across two communities: French-English fami ...

Article GUID: 42193667


Prevalence of Metabolically Healthy Obesity in Canadian Children and Adolescents at Entry to Pediatric Weight Management Clinic and One Year Later: A Secondary Analysis of CANadian Pediatric Weight Management Registry Data

Author(s): Cohen TR; Bains A; Ball GDC; Faustini C; Heidl A; Morrison KM;

Few studies have characterized metabolically healthy (MHO) and unhealthy obesity (MUO) in pediatric populations over time. The objective of this study was to determine the prevalence of MHO in children and adolescents enrolled in a weight management program and examine changes in cardiometabolic indicators over 1 year.Methods: Participants from the CANadi ...

Article GUID: 42189064


Prise en charge de la multimorbidité cœur-cerveau : un guide de pratique clinique

Author(s): Edwards JD; Li Z; McFarlane P; Rabi DM; Gilbert J; Bajaj HS; MacIntosh BJ; Bittman J; Feldman RD; Dresser G; Terenzi K; Swartz R; Gabor J; Pearson GJ; Selby P; Wharton S; Warburton DER; Pakhalé S; Styra R; Baker B; Tu K; Hawkins M; Stone ...

id="fra-abstract"> Contexte: Les maladies du cœur et les maladies du cerveau partagent divers facteurs de risque et elles coexistent souvent; pourtant, les guides de pratique clinique en cardiologie et en neurologie sont le plus souvent produits en silos disciplinaires. Élaboré par un g ...

Article GUID: 42185004


Is Pain Intensity Associated With Sleep-Spindle Activity in Persons With Chronic Spinal Pain and Chronic Insomnia Disorder? A Polysomnography Study

Author(s): Runge N; Walsh N; Dang-Vu TT; De Baets L; Labie C; Bilterys T; Verschueren S; Van Assche D; Nijs J; Malfliet A; Danneels L; Ickmans K; Moens M; Goubert D; Mairesse O; Paez A;

Chronic spinal pain is associated with fragmented sleep, yet the neurophysiological mechanisms linking the two remain unclear. Given their role in sensory gating and sleep stability, sleep spindles may represent a key mechanism connecting chronic spinal pain and sleep fragmentation. This study ex ...

Article GUID: 42186730


Practices to Reduce Stigma and Discrimination Towards Older Transitional Housing Clients

Author(s): Canham SL; Richardson LR; Aaenson-Fletcher J; Weldrick R; Walsh CA;

Homelessness remains an enduring social issue, in part, due to the stigmatization of and discrimination toward people experiencing homelessness, known as homeism. Despite extant research on the topic, little is known about how homeism, enacted through stigmatization and discrimination, may occur within transitional housing programs or among older people e ...

Article GUID: 42184413


Hand to Mouth: Shifting the Bare-Minimum Accessibility Paradigm in XR Through Crip-Hacking and Crip-Aesthetics

Author(s): Jain P; Bayerlein C;

eXtended Reality (XR) technologies often embed ableist design assumptions, privileging hand-based interaction and vision-centric interfaces that presume a normative able-bodied user. As a result, many disabled people-including those with limited mobility or blindness-are excluded from the outset, with accessibility added only as an afterthought. We critiq ...

Article GUID: 42182821


Time Management, Stigma, Jealousy, and More: A Content Analysis of the Challenges of Polyamory

Author(s): Boudreau P; Moors AC; McConnell L; Su K; Camilleri S;

Despite growing public and scientific interest in consensually non-monogamous (CNM) relationships, clinical and empirical understandings of the challenges faced by people who engage in polyamory remain limited. To address this gap, we conducted a content analysis of 763 open-ended responses from 219 individuals currently in a polyamorous relationship who ...

Article GUID: 42179042


Isatin-pyridine oxime hybrids as potential reactivators of A-242-inhibited acetylcholinesterase

Author(s): Pinto AMV; Bhattacharyya D; da Silva MCJ; Kitagawa DAS; Dos Santos MC; Cavalcante SFA; Islam ST; LaPlante SR; Forgione P; Diz JSF; França TCC;

Three new isatin-pyridine-2-oxime hybrids (AM01-03) were synthesized and experimentally evaluated as reactivators of acetylcholinesterase (AChE) inhibited by a surrogate of the nerve agent A-242, in comparison with their 4-oxime isomers previously reported by our research group. Furthermore, the ...

Article GUID: 42171685


A systematic literature review on IoT application layer protocol testing and future research directions

Author(s): Asgari Araghi M; Khendek F;

With the proliferation and the critical role of Internet of Things (IoT) in various domains, rigorous testing techniques are required for improving their quality. Several review studies have examined IoT topology and analyzed different layers of the IoT architecture. These assessments include synthesis on the application layer protocols, but do not specif ...

Article GUID: 42145937


Coronary Artery Disease Is Linked with Demyelination and Iron Deposition in White Matter Watershed Areas

Author(s): Rezaei A; Potvin-Jutras Z; Tremblay SA; Sanami S; Sabra D; Huck J; Gagnon C; Wright L; Leppert IR; Tardif CL; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ;

Coronary artery disease is associated with white matter alterations. However, the biological basis of these changes remains unclear, specifically in normal-appearing white matter. Myelin and iron content are crucial measures of white matter health and can be measured with quantitative MRI. This s ...

Article GUID: 42149094


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