PERFORM Publications

The effects of circadian desynchronization on alcohol consumption and affective behavior during alcohol abstinence in female rats

Author(s): Meyer C; Schoettner K; Amir S;

Disruption of circadian rhythmicity distorts physiological and psychological processes and has major consequences on health and well-being. A chronic misalignment within the internal time-keeping system modulates alcohol consumption and contributes to stres ...

Article GUID: 36620855

Characterization of Affective Behaviors and Motor Functions in Mice With a Striatal-Specific Deletion of Bmal1 and Per2

Author(s): Schoettner K; Alonso M; Button M; Goldfarb C; Herrera J; Quteishat N; Meyer C; Bergdahl A; Amir S; ...

The expression of circadian clock genes, either centrally or in the periphery, has been shown to play an integral role in the control of behavior. Brain region-specific downregulation of clock gene ...

Article GUID: 35755440

Thermoregulatory significance of immobility in the forced swim test

Author(s): Nadeau BG; Marchant EG; Amir S; Mistlberger RE;

The forced swim test (FST) is a widely used animal model of depression and antidepressant drug screen. Rats are forced to swim on two test days in a restricted space from which there is no escape. On the first test day the rats attempt to escape and then be ...

Article GUID: 35065081

Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner

Author(s): de Zavalia N; Schoettner K; Goldsmith JA; Solis P; Ferraro S; Parent G; Amir S;

Alcohol consumption has been strongly associated with circadian clock gene expression in mammals. Analysis of clock genes revealed a potential role of Bmal1 in the control of alcohol drinking behavior. However, a causal role of Bmal1 and neural pathways thr ...

Article GUID: 34702951

In utero Exposure to Valproic-Acid Alters Circadian Organisation and Clock-Gene Expression: Implications for Autism Spectrum Disorders

Author(s): Ferraro S; de Zavalia N; Belforte N; Amir S;

Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder characterised by restrictive patterns of behaviour and alterations in social interaction and communication. Up to 80% of children with ASD exhibit sleep-wake cycle disturbances, empha ...

Article GUID: 34650409

The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4.

Author(s): Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R

Neuron. 2019 Aug 26;: Authors: Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R

Article GUID: 31522764

Effects of bilateral anterior agranular insula lesions on food anticipatory activity in rats.

Author(s): Gavrila AM, Hood S, Robinson B, Amir S

PLoS One. 2017;12(6):e0179370 Authors: Gavrila AM, Hood S, Robinson B, Amir S

Article GUID: 28594962

Circadian Rhythms in Regulation of Brain Processes and Role in Psychiatric Disorders.

Author(s): Pantazopoulos H, Gamble K, Stork O, Amir S

Neural Plast. 2018;2018:5892657 Authors: Pantazopoulos H, Gamble K, Stork O, Amir S PMID: 29887881 [PubMed - indexed for MEDLINE]

Article GUID: 29887881

Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain.

Author(s): Frederick A, Goldsmith J, de Zavalia N, Amir S

PLoS One. 2017;12(4):e0176279 Authors: Frederick A, Goldsmith J, de Zavalia N, Amir S

Article GUID: 28423013

Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day.

Author(s): Harbour VL, Weigl Y, Robinson B, Amir S

PLoS One. 2013;8(10):e76391 Authors: Harbour VL, Weigl Y, Robinson B, Amir S

Article GUID: 24124556

Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat.