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Acute food deprivation-induced relapse to heroin seeking after short and long punishment-imposed abstinence in male rats

Author(s): Borges C; Inigo F; Quteishat N; Charles J; Ah-Yen E; U S;

Rational: Stress is a major trigger for drug relapse in humans and animal models, even after prolonged abstinence. However, animal models for stress-induced relapse were criticized for the lack of predictive and face validity.
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Article GUID: 35951079


The utility of maraviroc, an antiretroviral agent used to treat HIV, as treatment for opioid abuse? Data from MRI and behavioural testing in rats

Author(s): Iriah SC; Borges C; Shalev U; Cai X; Madularu D; Kulkarni PP; Ferris CF;

Background: Maraviroc is an antiretroviral agent and C-C chemokine coreceptor 5 (CCR5) antagonist that is currently used to treat human immunodeficiency virus. CCR5/ยต-opioid receptor heterodimerization suggests that maraviroc could be a tre ...

Article GUID: 34625487


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