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Augmenting glutamatergic, but not dopaminergic, activity in the nucleus accumbens shell disrupts responding to a discrete alcohol cue in an alcohol context

Author(s): Valyear MD; Brown A; Deyab G; Villaruel FR; Lahlou S; Caporicci-Dinucci N; Chaudhri N;

Discrete alcohol cues and contexts are relapse triggers for people with alcohol use disorder exerting particularly powerful control over behaviour when they co-occur. Here, we investigated the neural substrates subserving the capacity for alcohol-associated ...

Article GUID: 38185906


Context-induced renewal of passive but not active coping behaviours in the shock-probe defensive burying task

Author(s): Brown A; Martins M; Richard I; Chaudhri N;

Renewal is the return of extinguished responding after removal from the extinction context. Renewal has been extensively studied using classical aversive conditioning procedures that measure a passive freezing response to an aversive conditioned stimulus. H ...

Article GUID: 37095421


Neural correlates of recall and extinction in a rat model of appetitive Pavlovian conditioning

Author(s): Brown A; Villaruel FR; Chaudhri N;

Extinction is a fundamental form of inhibitory learning that is important for adapting to changing environmental contingencies. While numerous studies have investigated the neural correlates of extinction using Pavlovian fear conditioning and appetitive ope ...

Article GUID: 36496079


Optogenetic stimulation of infralimbic cortex projections to the paraventricular thalamus attenuates context-induced renewal

Author(s): Brown A; Chaudhri N;

Contexts associated with prior reinforcement can renew extinguished conditioned responding. The prelimbic (PL) and infralimbic (IL) cortices are thought to mediate the expression and suppression of conditioned responding, respectively. Evidence suggests tha ...

Article GUID: 36373226


Learning processes in relapse to alcohol use: lessons from animal models

Author(s): Valyear MD; LeCocq MR; Brown A; Villaruel FR; Segal D; Chaudhri N;

Rationale: Alcohol use is reliably preceded by discrete and contextual stimuli which, through diverse learning processes, acquire the capacity to promote alcohol use and relapse to alcohol use.
Objective: We review con ...

Article GUID: 36264342


The development of gaze following in monolingual and bilingual infants: A multi-laboratory study.

Author(s): Byers-Heinlein K, Tsui RK, van Renswoude D, Black AK, Barr R, Brown A, Colomer M, Durrant S, Gampe A, Gonzalez-Gomez N, Hay JF, Hernik M, Ja ...

Determining the meanings of words requires language learners to attend to what other people say. However, it behooves a young language learner to simultaneously encode relevant non-verbal cues, for ...

Article GUID: 33306867


Comparing ABA, AAB, and ABC Renewal of Appetitive Pavlovian Conditioned Responding in Alcohol- and Sucrose-Trained Male Rats.

Author(s): Khoo SY, Sciascia JM, Brown A, Chaudhri N

Front Behav Neurosci. 2020;14:5 Authors: Khoo SY, Sciascia JM, Brown A, Chaudhri N

Article GUID: 32116588


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