Author(s): Valyear MD; Brown A; Deyab G; Villaruel FR; Lahlou S; Caporicci-Dinucci N; Chaudhri N;

Discrete alcohol cues and contexts are relapse triggers for people with alcohol use disorder exerting particularly powerful control over behaviour when they co-occur. Here, we investigated the neural substrates subserving the capacity for alcohol-associated ...

Article GUID: 38185906

Author(s): Brown A; Villaruel FR; Chaudhri N;

Extinction is a fundamental form of inhibitory learning that is important for adapting to changing environmental contingencies. While numerous studies have investigated the neural correlates of extinction using Pavlovian fear conditioning and appetitive ope ...

Article GUID: 36496079

Author(s): Brown A; Chaudhri N;

Contexts associated with prior reinforcement can renew extinguished conditioned responding. The prelimbic (PL) and infralimbic (IL) cortices are thought to mediate the expression and suppression of conditioned responding, respectively. Evidence suggests tha ...

Article GUID: 36373226

Author(s): Valyear MD; LeCocq MR; Brown A; Villaruel FR; Segal D; Chaudhri N;

Rationale: Alcohol use is reliably preceded by discrete and contextual stimuli which, through diverse learning processes, acquire the capacity to promote alcohol use and relapse to alcohol use. Objective: We review contemporary extinction, renewal, reinsta ...

Article GUID: 36264342

Author(s): Segal D; Valyear MD; Chaudhri N;

This supplementary dataset is supportive of the research article entitled 'The role of context on responding to an alcohol-predictive cue in female and male rats' [1]. This article describes the raw data pertaining to the behaviour of male and femal ...

Article GUID: 35330738

Author(s): Villaruel FR; Martins M; Chaudhri N;

The capacity to suppress learned responses is essential for animals to adapt in dynamic environments. Extinction is a process by which animals learn to suppress conditioned responding when an expected outcome is omitted. The infralimbic cortex (IL) to nucle ...

Article GUID: 34880119

Author(s): LeCocq MR; Sun S; Chaudhri N;

Re-exposure to an unconditioned stimulus (US) can reinstate extinguished conditioned responding elicited by a conditioned stimulus (CS). We tested the hypothesis that the reinstatement of responding to an appetitive CS is driven by an excitatory association ...

Article GUID: 34852244

Author(s): Segal D; Valyear MD; Chaudhri N;

In male rats, physical contexts that are associated with alcohol can amplify responding to a discrete, alcohol-predictive conditioned stimulus (CS), and amplify prime-induced reinstatement. Here, we examined these effects as a function of biological sex. Ma ...

Article GUID: 34742865

Author(s): Cofresí RU, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ

The ability of environmental cues to trigger alcohol-seeking behaviors is believed to facilitate problematic alcohol use. We previously showed that the development of this cue-evoked alcohol approach reflects cue-alcohol learning and memory in the adult mal ...

Article GUID: 31002878

Author(s): Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N

Nat Commun. 2020 Jul 28;11(1):3764 Authors: Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N

Article GUID: 32724058

Author(s): Khoo SY, Sciascia JM, Brown A, Chaudhri N

Front Behav Neurosci. 2020;14:5 Authors: Khoo SY, Sciascia JM, Brown A, Chaudhri N

Article GUID: 32116588