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Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms

Author(s): Di Lorenzo B; Camargo Tavares L; Díaz-Muñoz C; Heredia-Fernández F; Bozzarelli I; Esteban Blanco C; Wang Z; Smit RAJ; Loos RJF; Hirbo J; Cox NJ; Straub P; Favé MJ; Awadalla P; Pozdeyev N; Gignoux CR; Gudbjartsson DF; Thorleifsson G; Jons ...

Background: Irritable bowel syndrome (IBS) is a complex disorder of gut-brain interaction, with heterogeneous symptoms, no available biomarkers and limited pathogenetic insight. Objective: To identify genetic risk factors and actionable mechanisms for future clinical translation in IBS. Design: ...

Article GUID: 42425734


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