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Improving candidate Biosynthetic Gene Clusters in fungi through reinforcement learning

Author(s): Almeida H; Tsang A; Diallo AB;

Motivation: Precise identification of Biosynthetic Gene Clusters (BGCs) is a challenging task. Performance of BGC discovery tools is limited by their capacity to accurately predict components belonging to candidate BGCs, often overestimatin ...

Article GUID: 35762945


TOUCAN: a framework for fungal biosynthetic gene cluster discovery.

Author(s): Almeida H, Palys S, Tsang A, Diallo AB

Fungal secondary metabolites (SMs) are an important source of numerous bioactive compounds largely applied in the pharmaceutical industry, as in the production of antibiotics and anticancer medications. The discovery of novel fungal SMs can potentially bene ...

Article GUID: 33575642


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