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Body temperature drives azole tolerance in Candida albicans by hindering the autophagic degradation of Erg11

Author(s): Feng Y; Zhen C; Li W; Whiteway M; Fang X; Shen X; Jiang Y; Lu H;

Human body temperature has been shown to limit the antifungal efficacy of azoles; however, the precise mechanisms underlying this limitation remain insufficiently understood. In this study, we observed that short-term exposure (24 h) to human body temperature (37 °C), in contrast to 30 °C, significantly enhances the tolerance of Candida albicans to azoles ...

Article GUID: 42361441


Understanding COVID-19 vaccination disparity among Black adults in North America: A two-study motivational approach

Author(s): Fang X; Holding AC; Audet ÉC; Thai H; Koestner R;

Previous research has revealed lower vaccination rates among Black communities relative to other racial-ethnic communities in North America. However, there remains a gap in understanding the motivational barriers contributing to these persistent disparities. Grounded in Self-Determination Theory, the current research aimed to examine the effects of differ ...

Article GUID: 41043306


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