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Transcriptional Profiling of the Candida albicans Response to the DNA Damage Agent Methyl Methanesulfonate

Author(s): Feng Y; Zhang Y; Li J; Omran RP; Whiteway M; Feng J;

The infection of a mammalian host by the pathogenic fungus Candida albicans involves fungal resistance to reactive oxygen species (ROS)-induced DNA damage stress generated by the defending macrophages or neutrophils. Thus, the DNA damage response in C. albi ...

Article GUID: 35886903


The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans

Author(s): Omran RP; Ramírez-Zavala B; Aji Tebung W; Yao S; Feng J; Law C; Dumeaux V; Morschhäuser J; Whiteway M; ...

Zinc cluster transcription factors are essential fungal regulators of gene expression. In the pathogen Candida albicans, the gene orf19.1604 encodes a zinc cluster transcription factor regulating f ...

Article GUID: 34849863


Loss of Arp1, a putative actin-related protein, triggers filamentous and invasive growth and impairs pathogenicity in Candida albicans.

Author(s): Yao S, Feng Y, Islam A, Shrivastava M, Gu H, Lu Y, Sheng J, Whiteway M, Feng J

The polymorphous cellular shape of Candida albicans, in particular the transition from a yeast to a filamentous form, is crucial for either commensalism or life-threatening infections of the host. Various external or internal stimuli, including serum and nu ...

Article GUID: 33363697


Nucleotide Excision Repair Protein Rad23 Regulates Cell Virulence Independent of Rad4 in Candida albicans.

Author(s): Feng J, Yao S, Dong Y, Hu J, Whiteway M, Feng J

mSphere. 2020 Feb 19;5(1): Authors: Feng J, Yao S, Dong Y, Hu J, Whiteway M, Feng J

Article GUID: 32075883


Hof1 plays a checkpoint related role in MMS induced DNA damage response in Candida albicans.

Author(s): Feng J, Islam A, Bean B, Feng J, Sparapani S, Shrivastava M, Goyal A, Omran RP, Mallick J, Whiteway M

Mol Biol Cell. 2020 Jan 15;:mbcE19060316 Authors: Feng J, Islam A, Bean B, Feng J, Sparapani S, Shrivastava M, Goyal A, Omran RP, Mallick J, Whiteway M

Article GUID: 31940254


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